Emerging bedaquiline resistance: A threat to the global fight against drug-resistant tuberculosis
March 2024
Bedaquiline resistance is increasingly observed in the treatment of rifampicin-resistant tuberculosis (TB), yet standardized regimens for managing bedaquiline-resistant TB are lacking. Studies indicate...
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Mosquito-borne diseases: Assessing risk and strategies to control their spread in the Middle East
March 2024
Mosquito-borne diseases (MBDs), like malaria and mosquito-borne viruses (MBVs), have caused the deaths of millions of people. Their threat resides in the variety of transmission modes that they possess,...
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Effectiveness of chemical inactivation of infectious liquid biological waste: A randomized sample study of research laboratories in Switzerland
March 2024
Laboratory wastewater has been suggested as an important escape route for microorganisms from research environments. Likely reasons for the unintentional release of laboratory organisms are shortcomings...
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Development and assessment of cutting-edge biotechnologies
March 2024
The emergence of advanced biotechnologies has intensified in recent years. The rapid development of these biotechnologies has had a wide and profound impact globally, with the majority on the frontier...
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Recurrent West Nile virus outbreak in the United States in 2022: Current challenges and recommendations
December 2023
West Nile virus (WNV) has afflicted various countries around the world, affecting not only humans but also non-human animals, such as horses and birds. WNV is an arbovirus that is transmitted to humans...
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Biosafety management in high-biosafety-risk workshops for vaccine production in China
December 2023
This paper examines biosafety management in high-biosafety-risk workshops for vaccine production in China, focusing on the context of SARS-CoV-2 inactivated vaccine production. It addresses various...
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Epidemiological modeling of Influenza-Like Illness (ILI) transmission in Jakarta, Indonesia through cumulative generating operator on SLIR model
December 2023
Influenza-Like Illness (ILI) constitutes a significant global health concern characterized by its high infection rates and widespread distribution worldwide. While influenza viruses, primarily types...
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Dual-use oversight: Is the scientific community fit for Purpose? What should be done if it is not?
December 2023
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Review of livestock biosecurity resources and trainings: Local, state, federal, and international organizations
December 2023
This study evaluates the accessibility and availability of publicly accessible biosecurity resources in the Fall of 2021, as part of the IN-PREPared and Gearing Up for Safety program. The research into...
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The 2023 International Workshop on Biosafety Laboratory Management and Techniques was held in Wuhan, China
December 2023
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Physico-chemical quality of ashes post-incineration and waste from laboratory automaton biochemistry, hematology and serology in Togo
September 2023
Biochemistry, hematology and serology laboratories produce very heterogeneous discharges capable of polluting water, soil and the environment. The aim of this study is to evaluate the physico-chemical...
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Allelic and genotypic analysis of the ACE I/D polymorphism for the possible prediction of COVID-19-related mortality and morbidity in Jordanian Arabs
September 2023
The coronavirus disease 2019 (COVID-19) pandemic has rapidly spread worldwide, posing a global medical concern. This novel RNA virus enters cells by binding to angiotensin-converting enzyme II (ACE2)...
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Strengthening the cross-cutting issue of the biological weapons convention in Pakistan
September 2023
Development and sharing of model approaches to national science policies can enable States Parties to effectively raise awareness about the security dimensions of life science research and to promote...
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Comparison of the binding energies of approved mpox drugs and phytochemicals through molecular docking, molecular dynamics simulation, and ADMET studies: An in silico approach
September 2023
•The binding affinity of Tecovirimat, Brincidofovir, Cidofovir against the mpox protein was examined in silico through molecular docking.•The binding affinity of such drugs/mAbs was compared with the...
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COVID’s future: Viral multi-lineage evolution and the dynamics of small epidemic waves without seasonality in COVID-19
September 2023
Since its emergence, SARS-CoV-2 virus, the causative agent of COVID-19, has undergone over three years of evolutionary changes. Throughout this evolutionary process, multiple variants, such as Alpha,...
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Rethinking biosecurity in the 21st century: An enhanced role for civil society
September 2023
In this paper, we briefly discuss the historical issues concerning the Biological and Toxin Weapons Convention (BTWC) and analyse the current situation after the COVID-19 pandemic with emphasis on the...
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Epidemiological and comparative genomic analyses of Multidrug-Resistant Acinetobacter baumannii collected between 2020 and 2022 in Liaocheng City, Shandong Province, China
June 2023
The emergence and prevalence of multidrug-resistant Acinetobacter baumannii (MRAB) poses a huge challenge to clinical treatment. To investigate the genetic and epidemiologic characteristics of MRAB...
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Outbreak of an emerging zoonotic Nipah virus: An emerging concern
June 2023
The Nipah virus (NiV) infection is one of the newly emerging deadly zoonotic diseases which carries a significant weightage of mortality among its victims. Due to the relatively recent history of its...
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Efficiency of surface inactivation disinfectants for bacteria studied in an aquaculture microbiology laboratory
June 2023
Routine microbial inactivation procedures used in microbiology laboratories must be verified. In this study, the efficacy of surface disinfection using 70% Isopropanol, 0.45% Presept, and 1% Virkon...
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Mobile biosafety level (BSL) 2 laboratories deployment: Strengthening the diagnostic facilities in Pakistan with emerging public health challenges and the way forward
June 2023
Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens, monitor its presence in certain populations and inform health authorities to take immediate remedial measures....
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The potential epidemic threat of Ebola virus and the development of a preventive vaccine
June 2023
Ebola virus (EBOV) is classified as a category A pathogen as it causes viral hemorrhagic fever, one of the most-deadly virus-related diseases. Since its discovery in 1976, EBOV has caused a number of...
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