Recent developments and trends of automatic nucleic acid detection systems
June 2022
Nucleic acid detection, widely used in clinical diagnosis, biological analysis, and environmental monitoring, is of great significance for disease diagnosis and basic research. With the outbreak of...
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Synthetic biology: Recent progress, biosafety and biosecurity concerns, and possible solutions
March 2019
Synthetic biology is a new interdisciplinary research area that uses engineering principles as guidelines for biological investigation. With research goals to modify existing biological systems or to...
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Biosafety and biosecurity in the era of biotechnology: The Middle East region
December 2022
Biotechnology became a paradigm-shifting science among all subfields of biology. The benefits of biotechnology have reached many practical fields, whether human health, animal, and/or agricultural....
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Optimization of cryopreservation of pathogenic microbial strains
December 2020
The preservation of pathogenic microbial strains is of great significance for basic research in microbiology and utilization of microbial resources. Appropriate preservation methods can maintain high...
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Biosafety and biosecurity
March 2019
With the profound changes in the international security situation, the progression of globalization, and the continuous advancement of biotechnology, the risks and challenges posed by major infectious...
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Water sanitation and hygiene in Sub-Saharan Africa: Coverage, risks of diarrheal diseases, and urbanization
June 2021
Sub-Saharan Africa (SSA) has a rapidly growing urban population, with water, sanitation, and hygiene (WASH) services representing the central needs for this population. Incidentally, this region has...
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Mosquito-borne diseases: Assessing risk and strategies to control their spread in the Middle East
March 2024
Mosquito-borne diseases (MBDs), like malaria and mosquito-borne viruses (MBVs), have caused the deaths of millions of people. Their threat resides in the variety of transmission modes that they possess,...
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Ethical framework on risk governance of synthetic biology
June 2023
Synthetic biology is an emerging multidisciplinary field that aims to design and construct new biological systems not found in nature. Whereas synthetic biology may yield tremendous benefits, it may...
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Laboratory information management system for biosafety laboratory: Safety and efficiency
June 2021
Laboratory information management system (LIMS) has been widely used to facilitate laboratory activities. However, the current LIMSs do not contain functions to improve the safety of laboratory work,...
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Stability analysis of a fractional-order monkeypox epidemic model with quarantine and hospitalization
March 2024
The monkeypox epidemic has become a global health issue due to its rapid transmission involving nonhuman-to-human transmission in nonendemic areas. Various actions, such as quarantine, vaccination,...
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Challenges and recent progress in the governance of biosecurity risks in the era of synthetic biology
June 2022
Considerable progress has been achieved in basic research and the biotechnological application of biological sciences in recent years. Synthetic biology integrates systems biology, engineering, computer...
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Emerging bedaquiline resistance: A threat to the global fight against drug-resistant tuberculosis
March 2024
Bedaquiline resistance is increasingly observed in the treatment of rifampicin-resistant tuberculosis (TB), yet standardized regimens for managing bedaquiline-resistant TB are lacking. Studies indicate...
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A review of the risk of cholera outbreaks and urbanization in sub-Saharan Africa
December 2020
The sub-Saharan region of Africa is rapidly urbanizing, that has consequently spurred the development of specific challenges in terms of access to basic services and sanitation. Thus, exposure to waterborne...
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Development of and prospects for the biological weapons convention
June 2022
Biological weapons are used in wars to wound or kill people or animals and destroy crops with pathogenic microorganisms such as bacteria and viruses, as well as toxins and other biologically active...
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A brief history of the development of infectious disease prevention, control, and biosafety programs in China
March 2020
Safety of human beings has always been threatened by infectious diseases. In the process of fighting them, humans have continuously explored and researched the pathogens, transmission routes, prevention,...
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Public awareness, participation and attitude toward the national biosafety framework and genetically modified organisms in Ghana
December 2021
Public engagement in the development, promotion, and utilization of innovation is an important part of any biosafety decision-making process. Under the Cartagena Protocol on Biosafety, the public is...
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Effectiveness of chemical inactivation of infectious liquid biological waste: A randomized sample study of research laboratories in Switzerland
March 2024
Laboratory wastewater has been suggested as an important escape route for microorganisms from research environments. Likely reasons for the unintentional release of laboratory organisms are shortcomings...
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Mobile biosafety level (BSL) 2 laboratories deployment: Strengthening the diagnostic facilities in Pakistan with emerging public health challenges and the way forward
June 2023
Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens, monitor its presence in certain populations and inform health authorities to take immediate remedial measures....
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Deliberate release: Plague – A review
March 2020
Yersinia pestis is the causative agent of plague and is considered one of the most likely pathogens to be used as a bioweapon. In humans, plague is a severe clinical infection that can rapidly progress...
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Assessing decontamination practices at a medical microbiology research laboratory
December 2022
To our knowledge, this is the first study to conduct an objective assessment of the routine decontamination practices at a medical microbiology research laboratory (MRL) a year after a biosafety training...
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Applications of the One Health concept: Current status in the Middle East
March 2023
•The concept of One Health is one of the most important topics of modern health that the world seeks to apply.•Manitaining and enhancing human, plant, and animal health from the aspect of One Health.•The...
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Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
March 2023
How to ensure the safe, effective, and ethical use of emerging biotechnologies, such as clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing, is a global challenge....
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Regulation of Toxins and Bioregulators Under the Chemical Weapons Convention and the Biological and Toxin Weapons Convention
Available online 30 March 2024
In this paper we highlight how the apparent double coverage of toxins and bioregulators by both the Biological and Toxin Weapons Convention (BTWC) and the Chemical Weapons Convention (CWC) in fact masks...
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Comparison of the binding energies of approved mpox drugs and phytochemicals through molecular docking, molecular dynamics simulation, and ADMET studies: An in silico approach
September 2023
•The binding affinity of Tecovirimat, Brincidofovir, Cidofovir against the mpox protein was examined in silico through molecular docking.•The binding affinity of such drugs/mAbs was compared with the...
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Overview and prospects of food biosafety
December 2022
Biosafety issues have become a major threat to the health of humans, animals, and ecosystems worldwide. As problems with food production and the food supply chain have become of greater concern to consumers,...
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