Preparation of ZnO nanoparticles from Juglans regia dry husk extract for biomedical applications
March 2025
The worldwide problem of antibiotic resistance threatens public health, necessitating the search for antimicrobial agents that are not only effective against antibiotic-resistant bacteria but also harmless...
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A targeted vaccination strategy: Integrating vaccines into biosafety, biosecurity, and one health initiatives
March 2025
Vaccination has saved millions of lives and is regarded as one of modern medicine’s most important successes. Effective vaccination programs should be based on risk assessment that considers demographic...
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Pseudovirus technology in global health: A critical need for robust biosecurity measures
December 2024
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Genetic diversity, virulence profiles, and antimicrobial resistance of Salmonella enterica serovar Typhi isolated from typhoid fever patients in Baghdad, Iraq
December 2024
Typhoid fever is an important health issue in developing countries, and the pathogenicity of Salmonella enterica serovar Typhi (S. ser. Typhi) depends on the presence of different virulence factors....
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Numerical simulations of a two-strain dengue model to investigate the efficacy of the deployment of Wolbachia-carrying mosquitoes and vaccination for reducing the incidence of dengue infections
December 2024
This study investigated the usefulness of a two-serotype dengue mathematical model to gain insights into the effects of antibody-dependent enhancement and temperature on dengue transmission dynamics...
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A stochastic epidemic model with time delays and unreported cases based on Markovian switching
December 2024
Disease dynamics are influenced by changes in the environment. In this study, unreported cases (U), environmental perturbations, and exogenous events are included in the epidemic Susceptible–Exposed–Infectious–Unreported–Removed...
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Lessons for biosecurity education from the International Nuclear Security Education Network
December 2024
With the rapid advances in technology and life science, biological security is now at a defining moment. The mandate of the 2022 Biological and Toxin Weapons Convention 9th Review Conference emphasised...
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Transformative advances in veterinary laboratory practices: Evaluating the impact of preliminary training in Khyber Pakhtunkhwa and Balochistan provinces of Pakistan
December 2024
Veterinary laboratories face distinct challenges in Pakistan, including inadequate infrastructure, resources, and training opportunities, especially in the Khyber Pakhtunkhwa and Balochistan regions....
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Estimation methods of reproduction numbers for epidemics of varying strains of COVID-19
December 2024
The estimation methods of reproduction numbers and serial intervals are important in the early stages of infectious diseases. During the COVID pandemic, China implemented a dynamic zero-COVID policy...
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Adherence to Biosafety and Biosecurity Protocols: An Assessment of Biomedical and Veterinary Laboratories in Benin
Available online 17 December 2024
Diagnostic laboratories play a crucial role in surveillance and epidemic preparedness. However, gaps in adherence to biosecurity and biosafety protocols in managing, isolating, storing, and disposing...
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The association between mycotic pneumonia and neonatal septicemia
September 2024
Candida species are the fourth most common etiological agents of late-onset infection in the neonatal intensive care unit (NICU) and are responsible for considerable morbidity and mortality....
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Modeling and optimal control of COVID-19 with comorbidity and three-dose vaccination in Indonesia
September 2024
This paper presents and examines a COVID-19 model that takes comorbidities and up to three vaccine doses into account. We analyze the stability of the equilibria, examine herd immunity, and conduct...
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Addressing poxvirus challenges in the Middle East to enhance biosafety and biosecurity measures
September 2024
The emergence and zoonotic transmission of poxviruses in the Middle East have been recognized as complex public health issues. Poxviruses, a vast family of DNA viruses, can infect many hosts, including...
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A mathematical model for a disease outbreak considering waning-immunity class with nonlinear incidence and recovery rates
September 2024
In the spread of infectious diseases, intervention levels play a crucial role in shaping interactions between healthy and infected individuals, leading to a nonlinear transmission process. Additionally,...
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Structure-based discovery of F. religiosa phytochemicals as potential inhibitors against Monkeypox (mpox) viral protein
September 2024
•The interaction of the A42R profilin-like protein with six phytochemicals found in an medicinal plant Ficus religiosa was studied.•Protein-ligand binding energies, IC50 values, ADMET characteristics,...
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Exploring the Interplay Between Social Awareness and the Use of Bed Nets in a Malaria Control Program
September 2024
This research aims to understand the effect of human awareness and the use of bed nets on malaria control programs. A deterministic host-vector mathematical model was utilized and simplified using the...
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Computational modeling and inhibition of SARS-COV-2 Papain-like protease enzyme: A potential therapeutic approach for COVID-19
September 2024
This study aims to investigate the potential impact of inhibitors targeting the papain-like protease (PLpro) of SARS-CoV-2 on viral replication and the host immune response. A mathematical model was...
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Dynamic evolution of an SVEIR model with variants and non-pharmaceutical interventions for controlling COVID-19
June 2024
The epidemiological characteristics and distributions of two epidemics in Fujian Province of Southeast China were attributed to the complex interactions among variant, host, and non-pharmaceutical interventions...
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Kalman filter based on a fractional discrete-time stochastic augmented CoVid-19 model
June 2024
In this paper, we study the dynamics of the CoVid-19 outbreak in Semarang, Indonesia, using a fractional CoVid-19 model. We first determine the effects of the isolation rate ∊ and infection rate β on...
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Regulation of toxins and bioregulators under the Chemical Weapons Convention and the Biological and Toxin Weapons Convention
June 2024
In this paper we highlight how the apparent double coverage of toxins and bioregulators by both the Biological and Toxin Weapons Convention (BTWC) and the Chemical Weapons Convention (CWC) in fact masks...
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Chi-square automatic interaction detection (CHAID) analysis of the use of safety goggles and face masks as personal protective equipment (PPE) to protect against occupational biohazards
June 2024
This study represents the first Spanish investigation to rigorously evaluate compliance with the use of safety goggles and face masks as essential personal protective equipment (PPE) in companies with...
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Analyzing co-infection dynamics: A mathematical approach using fractional order modeling and Laplace-Adomian decomposition
June 2024
The co-infection of HIV and COVID-19 is a pressing health concern, carrying substantial potential consequences. This study focuses on the vital task of comprehending the dynamics of HIV-COVID-19 co-infection,...
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Stability analysis of a fractional-order monkeypox epidemic model with quarantine and hospitalization
March 2024
The monkeypox epidemic has become a global health issue due to its rapid transmission involving nonhuman-to-human transmission in nonendemic areas. Various actions, such as quarantine, vaccination,...
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