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Recent Articles

Predicting anti-cancer drug sensitivity through WRE-XGBoost algorithm with weighted feature selection

Triplet therapy overcomes 3rd-EGFR TKI-resistant EGFR-L858R/T790M/C797S in trans and in cis/L718Q mutation

Reduction of Atp5b protects mice from diet-induced obesity

Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity

TMEM132E ablation suppresses tumor progression and restores tamoxifen sensitivity by inducing ERα expression in triple-negative breast cancer

Transcriptional programs associated with luminal play a vital role in invasive mucinous lung adenocarcinoma

Expanding the spectrum of novel candidate genes using trio exome sequencing and identification of monogenic cause in 27.5% of 320 families with steroid-resistant nephrotic syndrome

A novel metabolite-interacting protein (MIP)-based molecular subtyping construction and validation of IGFBP3 as a MIP-related oncogene in colorectal cancer

Unique presentation of a novel gain-of-function mutation in MTOR

The important role and core marker gene of tumor-infiltrating plasma cells in the microenvironment of lung adenocarcinoma

Glucose metabolism perturbations influence tumor microenvironments via LINC01139 pathway and facilitate immunotherapy in hepatocellular carcinoma

TULP4 degrades RYBP to enhance DNA damage repair and chemosensitivity of pancreatic ductal adenocarcinoma

NOP56 promotes hepatocellular carcinoma progression through 2′-O-methylation

BBOX1, LACC1, MMP7 and SSTR1 as common predictors in obesity and non-alcoholic fatty liver disease

The AKT1-mTOR signaling cascade is crucial for SOX3 to promote hepatocarcinogenesis

PinX1 suppresses cancer progression by inhibiting telomerase activity in cervical squamous cell carcinoma and endocervical adenocarcinoma

Newly identified intronic and known pathogenic point mutations in SLC34A3/NPT2c cause hereditary hypophosphatemic rickets with hypercalciuria

Concurrent PIK3CA and IDH1 variants in facial infiltrating lipomatosis with intracranial lesions

SET-NUP214-induced hypermethylation landscape promotes abnormal overexpression of HOXC cluster genes in acute megakaryoblastic leukemia

Whole exome sequencing identifies KCNH7 variants associated with epilepsy in children

Construction and validation of a novel SUMOylation-related lncRNAs signature for predicting the prognosis, tumor immune microenvironment, and therapeutic sensitivity of lung adenocarcinoma

SNORD3B-2 promotes endometrial carcinoma progression by 2′-O-methylation modification of PLK1 and regulating RAB17 alternative splice

De novo missense variants of UNC13A are implicated in epileptic encephalopathies and neurodevelopmental disorders

Identification of hypermethylated CpG sites mapped to LIFR as specific diagnostic biomarkers of colon cancer

Investigation of the genome-wide signatures underlying the micropapillary carcinoma components in colorectal cancers

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