Recent Articles

The abnormal splicing regulation network caused by synonymous mutations in FBN1 exon 39 leads to Marfan syndrome

May 2025

Fudan Wu | Mingjie Li | Xuan Zhou | Qianyun Wang | Yan'an Wu

Phosphorylation-related genes in lupus nephritis: Single-cell and machine learning insights

May 2025

Lisha Mou | Zhihao Chen | Xinran Tian | Yupeng Lai | Zuhui Pu | Meiying Wang

Prognostic significance and multidimensional roles of interferon regulatory factors in cancer biology: A comprehensive analysis

May 2025

Guo Ji | Shuyuan Xian | Jiaqi Song | Shiyu Mao | Man Pi | Qiongyi Huang | Xue Han | Jian Yin | Zan Wu | Runzhi Huang | Dongyan Han | Zhengyan Chang

Role of PFKM lactylation in glycolysis regulation in endometrial cancer cells

May 2025

Bin Wang | Jian Ma | Di Yang

HOXB6 down-regulation induced by retinoic acid pathway repression leads to chondrocyte proliferation inhibition and apoptosis in microtia

May 2025

Run Yang | Xin Chen | Siyi Wu | Chenlong Li | Ying Chen | Yaoyao Fu | Aijuan He | Duan Ma | Jing Ma | Tianyu Zhang

Construction of a prognostic model based on the cuproptosis-related genes in pancreatic cancer

May 2025

Kaili Liao | Yuxin Fu | Shuman Guo | Tingyi Qian | Feifei Teng | Yuhan Xu | Bing Sun | Hanqing Zhao | Jingyan Zhang | Ranhao Fan | Jie Gao | Xiaozhong Wang

AUTS2 expression within mammalian lineage: A predictor of neural networks involved in autism spectrum disorders

May 2025

Aude-Marie Lepagnol-Bestel | Yann Loe-Mie | Mounia Bensaid | Michel Simonneau

Shikonin is a novel antagonist of prostaglandin E2 receptor 4 that targets myeloid-derived suppressor cells

May 2025

Yang Wang | Naijipu Abuduaini | Wenjuan Liu | Yuanjun Song | Zunping Ke | Xilong Wang | Wei Jiao | Si Chen | Xianhua Lin | Weiwei Yu | Weiqiang Lu | Bo Feng | Jiacheng He

A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy

May 2025

Wei Zhang | Yibao Fan | Milad Ashrafizadeh | Dan Shi | Gautam Sethi | Yavuz Nuri Ertas | A.M. Abd El-Aty | Xianbin Zhang | Si Chen | Peng Gong

Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma

May 2025

Jie Li | Yuyuan Zhang | Jinhai Deng | Siyuan Weng | Hui Xu | Yuhao Ba | Anning Zuo | Shutong Liu | Quan Cheng | Jian Zhang | Peng Luo | Zhen Li | Xinwei Han | Zaoqu Liu

A novel research model of clonal evolution in mantle cell lymphoma at the single-cell genomic level

May 2025

Li Zhang | Yongsheng Liu | Liang Wang | Li Wang | Li Zheng | Wei He | Li Yan | Lvsu Ye | Huidan Zhang | Junling Tang

Targeting MUC1 with fisetin in oral squamous cell carcinoma

May 2025

Qian Wang | Hongyan Zhang | Shuzhen Xiang | Lan Zhang | Jiajia Fan | Zengyan Xu | Fengfei Zhao | Minda Liu | Yanshu Li | Wei Dai

Tnni3k regulates cardiomyopathy and cardiac conduction disease through Nfatc1 signaling

May 2025

Shi Ouyang | Yujuan Niu | Le Liu | Qiaorong Yi | Wuming Qin | Hui Cao | Tao Liao | Rong Xiang | Yonghe Ding | Yun Deng

Assessment of the transcriptomic consequences and MAU2 protein levels in edited induced pluripotent stem cells with NIPBL pathogenic variants

May 2025

Kévin Cassinari | Anne Rovelet-Lecrux | Céline Derambure | Myriam Vezain | Sophie Coutant | Anne-Claire Richard | Nathalie Drouot | Juliette Coursimault | Gabriella Vera | Alice Goldenberg | Pascale Saugier-Veber | Camille Charbonnier | Gaël Nicolas

Inflammatory transcriptomic signatures and cell type compositions in inflamed and non-inflamed colonic mucosa of ulcerative colitis

May 2025

Eun Mi Song | Jahanzeb Saqib | Yang Hee Joo | Zehra Ramsha | Chang Mo Moon | Sung-Ae Jung | Junil Kim

Novel compound heterozygous TTN gene variants with additional potential contributory mutations in two sisters with severe scoliosis: A case report

May 2025

Huaiyuan Wang | Shengjie Li | Weiyun Chen | Jianxiong Shen

Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling

May 2025

Ailing Hao | Xiangyu Dong | Yannian Gou | Aohua Li | Jiajia Li | Han Xiang | Saidur Rahaman | Yi Zhu | Hui Zhang | Wulin You | Guowei Shen | Changqi Luo | Ou Mei | Xingye Wu | Lewis L. Shi | Russell R. Reid | Tong-Chuan He | Jiaming Fan

ADAM8 inactivation modulates cellular component assembly gene expression in the mouse intervertebral disc

May 2025

Ken Chen | Zuozhen Tian | Motomi Enomoto-Iwamoto | Yejia Zhang

Utilization of cuproptosis-related lncRNAs to predict the prognosis of pancreatic cancer patients and explore their roles in immune cell infiltration and prognosis evaluation

May 2025

Kaili Liao | Jinting Cheng | Xiajing Yu | Ziqian Liu | Xue Zhang | Yuxin Fu | Wenyige Zhang | Jie Liu | Feifei Teng | Yuxuan Xie | Xiwen Yan | Gaoquan Cao | Bing Sun | Hanqing Zhao | Jingyan Zhang | Xiaozhong Wang

Allele-specific methylation of the PSA promoter in prostate cells: A new translational marker for the differential diagnosis of prostate cancer

May 2025

Mikhail Baryshev | Irina Maksimova | Ilona Sasoveca

Hub genes identification for diagnosing Alzheimer's disease in patients with Crohn's disease

May 2025

Pei Liu | Xiaoying Yao | Hongyan Wang

Transcription factors, metabolic dysfunction-associated fatty liver disease, and therapeutic implications

May 2025

Shuwei Hu | Yingjie Ai | Chencheng Hu | Fathima N. Cassim Bawa | Yanyong Xu

Metabolic dysfunction-associated fatty liver disease (MAFLD) encompasses a spectrum of liver diseases ranging from metabolic dysfunction-associated fatty liver to metabolic dysfunction-associated steatohepatitis,...

In vivo consequences of varying degrees of OTOA alteration elucidated using knock-in mouse models and pseudogene contamination-free long-read sequencing

May 2025

Ju Ang Kim | Bong Jik Kim | Chung Lee | Go Hun Seo | Hane Lee | Jin Hee Han | Ava Niazi | Joosang Park | Byung Yoon Choi | Sungjin Park