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ISSN: 2352-3042
CN: 50-1221/R
p-ISSN: 2352-4820

Unraveling RUNX2 mutation in a cleidocranial dysplasia patient: Molecular insights into osteogenesis and proteostasis

July 2025

Luca Dalle Carbonare | Arianna Minoia | Alberto Gandini | Francesca Cristiana Piritore | Cristina Patuzzo | Lucrezia Ceretti | Anna Vareschi | Antonino Aparo | Mattia Cominacini | Giovanni Malerba | Maria Grazia Romanelli | Joao Pessoa | Daniele Guardavaccaro | Franco Antoniazzi | Maria Teresa Valenti

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OSdream: An online survival and differential analysis tool of recurrence and metastasis of pan-cancers

July 2025

Huimin Li | Qiang Wang | Yunyi Liu | Lin Chen | Qiwei Zhao | Longxiang Xie | Lu Zhang | Zhongyi Yan | Guosen Zhang | Yali Han | Wan Zhu | Xiangqian Guo

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Clinically relevant variants detected in Chinese children with global developmental delay/intellectual disability: An exome-wide sequencing study

July 2025

Yimeng Qiao | Nan Lv | Tongchuan Li | Ye Cheng | Yunqian Li | Jiqiang Dong | Meimei Han | Yang Gu | Qing Shang | Qinghe Xing

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GATA2 up-regulation restores androgen receptor chromatin association and advances darolutamide resistance in prostate cancer

July 2025

Tianyi Zhou | Chengtai Yu | Yali Han | Bin He | Qin Feng

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Exploring the role of FTO in preeclampsia pathogenesis: Insights into m6A modification and decidualization

July 2025

Jing Tong | Liang Zhang | Jing Bai | Cong Zhang

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CRISPR/Cas9 screening reveals Zfp607b as a novel transcription factor regulating myogenesis

July 2025

Siyuan Liu | Wei Wang | Zishuai Wang | Chao Yan | Guohao Han | Weiwei Liu | Yuxing Huang | Wangchang Li | Shengsong Xie | Zhonglin Tang

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IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer progression

July 2025

Yihong Wei | Ying Xu | Yanqiong Zeng | Amin Zhang | Xiangling Xing | Wancheng Liu

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Runx2 controls the osteogenic fate of growth plate chondrocytes

May 2025

Daofu Zeng | Jiamin Yu | Ke Lu | Dan Yi | Zhidao Xia | Ling Qin | Guozhi Xiao | Xiao Yang | Liping Tong | Di Chen

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EWSR1-PSMC5 fusion gene variously activating autophagy in drug resistance of osteosarcoma: A novel gene fusion model report and mechanism research

May 2025

Qing Pan | Wenbo Yang | Fuhua Huang | Wei Wu | Zengwu Shao | Zhicai Zhang

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The abnormal splicing regulation network caused by synonymous mutations in FBN1 exon 39 leads to Marfan syndrome

May 2025

Fudan Wu | Mingjie Li | Xuan Zhou | Qianyun Wang | Yan'an Wu

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Phosphorylation-related genes in lupus nephritis: Single-cell and machine learning insights

May 2025

Lisha Mou | Zhihao Chen | Xinran Tian | Yupeng Lai | Zuhui Pu | Meiying Wang

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Prognostic significance and multidimensional roles of interferon regulatory factors in cancer biology: A comprehensive analysis

May 2025

Guo Ji | Shuyuan Xian | Jiaqi Song | Shiyu Mao | Man Pi | Qiongyi Huang | Xue Han | Jian Yin | Zan Wu | Runzhi Huang | Dongyan Han | Zhengyan Chang

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Role of PFKM lactylation in glycolysis regulation in endometrial cancer cells

May 2025

Bin Wang | Jian Ma | Di Yang

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Construction of a prognostic model based on the cuproptosis-related genes in pancreatic cancer

May 2025

Kaili Liao | Yuxin Fu | Shuman Guo | Tingyi Qian | Feifei Teng | Yuhan Xu | Bing Sun | Hanqing Zhao | Jingyan Zhang | Ranhao Fan | Jie Gao | Xiaozhong Wang

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AUTS2 expression within mammalian lineage: A predictor of neural networks involved in autism spectrum disorders

May 2025

Aude-Marie Lepagnol-Bestel | Yann Loe-Mie | Mounia Bensaid | Michel Simonneau

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Shikonin is a novel antagonist of prostaglandin E2 receptor 4 that targets myeloid-derived suppressor cells

May 2025

Yang Wang | Naijipu Abuduaini | Wenjuan Liu | Yuanjun Song | Zunping Ke | Xilong Wang | Wei Jiao | Si Chen | Xianhua Lin | Weiwei Yu | Weiqiang Lu | Bo Feng | Jiacheng He

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A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy

May 2025

Wei Zhang | Yibao Fan | Milad Ashrafizadeh | Dan Shi | Gautam Sethi | Yavuz Nuri Ertas | A.M. Abd El-Aty | Xianbin Zhang | Si Chen | Peng Gong

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Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma

May 2025

Jie Li | Yuyuan Zhang | Jinhai Deng | Siyuan Weng | Hui Xu | Yuhao Ba | Anning Zuo | Shutong Liu | Quan Cheng | Jian Zhang | Peng Luo | Zhen Li | Xinwei Han | Zaoqu Liu

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A novel research model of clonal evolution in mantle cell lymphoma at the single-cell genomic level

May 2025

Li Zhang | Yongsheng Liu | Liang Wang | Li Wang | Li Zheng | Wei He | Li Yan | Lvsu Ye | Huidan Zhang | Junling Tang

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Targeting MUC1 with fisetin in oral squamous cell carcinoma

May 2025

Qian Wang | Hongyan Zhang | Shuzhen Xiang | Lan Zhang | Jiajia Fan | Zengyan Xu | Fengfei Zhao | Minda Liu | Yanshu Li | Wei Dai

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Tnni3k regulates cardiomyopathy and cardiac conduction disease through Nfatc1 signaling

May 2025

Shi Ouyang | Yujuan Niu | Le Liu | Qiaorong Yi | Wuming Qin | Hui Cao | Tao Liao | Rong Xiang | Yonghe Ding | Yun Deng

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Assessment of the transcriptomic consequences and MAU2 protein levels in edited induced pluripotent stem cells with NIPBL pathogenic variants

May 2025

Kévin Cassinari | Anne Rovelet-Lecrux | Céline Derambure | Myriam Vezain | Sophie Coutant | Anne-Claire Richard | Nathalie Drouot | Juliette Coursimault | Gabriella Vera | Alice Goldenberg | Pascale Saugier-Veber | Camille Charbonnier | Gaël Nicolas

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Inflammatory transcriptomic signatures and cell type compositions in inflamed and non-inflamed colonic mucosa of ulcerative colitis

May 2025

Eun Mi Song | Jahanzeb Saqib | Yang Hee Joo | Zehra Ramsha | Chang Mo Moon | Sung-Ae Jung | Junil Kim

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Novel compound heterozygous TTN gene variants with additional potential contributory mutations in two sisters with severe scoliosis: A case report

May 2025

Huaiyuan Wang | Shengjie Li | Weiyun Chen | Jianxiong Shen

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Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling

May 2025

Ailing Hao | Xiangyu Dong | Yannian Gou | Aohua Li | Jiajia Li | Han Xiang | Saidur Rahaman | Yi Zhu | Hui Zhang | Wulin You | Guowei Shen | Changqi Luo | Ou Mei | Xingye Wu | Lewis L. Shi | Russell R. Reid | Tong-Chuan He | Jiaming Fan

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