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ISSN: 2352-3042

CN: 50-1221/R

p-ISSN: 2352-4820

Runx2 controls the osteogenic fate of growth plate chondrocytes

May 2025

Daofu Zeng | Jiamin Yu | Ke Lu | Dan Yi | Zhidao Xia | Ling Qin | Guozhi Xiao | Xiao Yang | Liping Tong | Di Chen

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EWSR1-PSMC5 fusion gene variously activating autophagy in drug resistance of osteosarcoma: A novel gene fusion model report and mechanism research

May 2025

Qing Pan | Wenbo Yang | Fuhua Huang | Wei Wu | Zengwu Shao | Zhicai Zhang

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The abnormal splicing regulation network caused by synonymous mutations in FBN1 exon 39 leads to Marfan syndrome

May 2025

Fudan Wu | Mingjie Li | Xuan Zhou | Qianyun Wang | Yan'an Wu

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Phosphorylation-related genes in lupus nephritis: Single-cell and machine learning insights

May 2025

Lisha Mou | Zhihao Chen | Xinran Tian | Yupeng Lai | Zuhui Pu | Meiying Wang

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Prognostic significance and multidimensional roles of interferon regulatory factors in cancer biology: A comprehensive analysis

May 2025

Guo Ji | Shuyuan Xian | Jiaqi Song | Shiyu Mao | Man Pi | Qiongyi Huang | Xue Han | Jian Yin | Zan Wu | Runzhi Huang | Dongyan Han | Zhengyan Chang

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Role of PFKM lactylation in glycolysis regulation in endometrial cancer cells

May 2025

Bin Wang | Jian Ma | Di Yang

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HOXB6 down-regulation induced by retinoic acid pathway repression leads to chondrocyte proliferation inhibition and apoptosis in microtia

May 2025

Run Yang | Xin Chen | Siyi Wu | Chenlong Li | Ying Chen | Yaoyao Fu | Aijuan He | Duan Ma | Jing Ma | Tianyu Zhang

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Construction of a prognostic model based on the cuproptosis-related genes in pancreatic cancer

May 2025

Kaili Liao | Yuxin Fu | Shuman Guo | Tingyi Qian | Feifei Teng | Yuhan Xu | Bing Sun | Hanqing Zhao | Jingyan Zhang | Ranhao Fan | Jie Gao | Xiaozhong Wang

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AUTS2 expression within mammalian lineage: A predictor of neural networks involved in autism spectrum disorders

May 2025

Aude-Marie Lepagnol-Bestel | Yann Loe-Mie | Mounia Bensaid | Michel Simonneau

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Predicting anti-cancer drug sensitivity through WRE-XGBoost algorithm with weighted feature selection

March 2025

Yiyao Jiang | Ming Chen | Zhongmin Xiong | Yufang Qin

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Triplet therapy overcomes 3rd-EGFR TKI-resistant EGFR-L858R/T790M/C797S in trans and in cis/L718Q mutation

March 2025

Kaibo Ding | Zhongsheng Peng | Yanjun Xu

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Reduction of Atp5b protects mice from diet-induced obesity

March 2025

Xiaohua Huang | Binting Qin | Zhengfeng Fang | Lianqiang Che | Yan Lin | Shengyu Xu | Yong Zhuo | Lun Hua | Xuemei Jiang | Mengmeng Sun | Hairui Wang | De Wu | Qingqiang Long | Bin Feng

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Transcriptional programs associated with luminal play a vital role in invasive mucinous lung adenocarcinoma

March 2025

Shufan Zhang | Rong Jiang | Changguo Wang | Manqiu Yang | Tao Wang | Jianzhou Cui | Guangbin Li | Shaomu Chen | Moli Huang

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Expanding the spectrum of novel candidate genes using trio exome sequencing and identification of monogenic cause in 27.5% of 320 families with steroid-resistant nephrotic syndrome

March 2025

Ronen Schneider | Shirlee Shril | Florian Buerger | Konstantin Deutsch | Kirollos Yousef | Camille N. Frank | Ana C. Onuchic-Whitford | Thomas M. Kitzler | Youying Mao | Verena Klämbt | Muhammad Y. Zahoor | Katharina Lemberg | Amar J. Majmundar | Bshara Mansour | Ken Saida | Steve Seltzsam | Caroline M. Kolvenbach | Lea Maria Merz | Nils D. Mertens | Tobias Hermle | Nina Mann | Dalia Pantel | Abdul A. Halawi | Aaron Bao | Luca Schierbaum | Sophia Schneider | Daanya Salmanullah | Iddo Z. Ben-Dov | Itamar Sagiv | Loai A. Eid | Hazem Subhi H. Awad | Muna Al Saffar | Neveen A. Soliman | Marwa M. Nabhan | Jameela A. Kari | Sherif El Desoky | Mohamed A. Shalaby | Said Ooda | Hanan M. Fathy | Shrikant Mane | Richard P. Lifton | Michael J.G. Somers | Friedhelm Hildebrandt

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A novel metabolite-interacting protein (MIP)-based molecular subtyping construction and validation of IGFBP3 as a MIP-related oncogene in colorectal cancer

March 2025

Simeng Bao | Yongmin Li | Yu Liang | Jianxun Dai | Huolin Huang | Bin Ma

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Unique presentation of a novel gain-of-function mutation in MTOR

March 2025

Samira Slimani | Alex G.I. Gagnon | Simon V. Schreiber | Nicolas A.D. Bergeron | Ludwig Haydock | Sébastien Labonté | Marc-Étienne Huot | Alexandre P. Garneau | Guillaume Canaud | Paul Isenring

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The important role and core marker gene of tumor-infiltrating plasma cells in the microenvironment of lung adenocarcinoma

March 2025

Jianhong Zhang | Chengyang Song | Xiuqin Feng | Qian Yu | Xueying Yang

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Glucose metabolism perturbations influence tumor microenvironments via LINC01139 pathway and facilitate immunotherapy in hepatocellular carcinoma

March 2025

Yueying Gao | Jinyang Yu | Zhi Li | Kefan Liu | Jiwei Pan | Ya Zhang | Yanlin Ma | Jiwei Zhang | Zhigang Liu | Yongsheng Li

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The AKT1-mTOR signaling cascade is crucial for SOX3 to promote hepatocarcinogenesis

March 2025

Yang Liu | Feifei Song | Xianhuang Zeng | Siqi Yang | Zixu Zhai | Ze Wang | Wajeeha Naz | Tanzeel Yousaf | Junwei Sun | Yangjun Zhang | Ying Zhou | Mingxiong Guo | Yun-Bo Shi | Geng Tian | Guihong Sun

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PinX1 suppresses cancer progression by inhibiting telomerase activity in cervical squamous cell carcinoma and endocervical adenocarcinoma

March 2025

Yue Weng | Xiangyu Yan | Biying Chen | Zhouliang Bian | Yunhui Ge | Hong Lu | Shufang He | Jian Wu | Yong Chen | Ming Lei | Yanjie Zhang

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Newly identified intronic and known pathogenic point mutations in SLC34A3/NPT2c cause hereditary hypophosphatemic rickets with hypercalciuria

March 2025

Yujing Sun | Yuan Liu | Xiaoli Zhang | Ling Jiang

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SET-NUP214-induced hypermethylation landscape promotes abnormal overexpression of HOXC cluster genes in acute megakaryoblastic leukemia

March 2025

Akhilesh Kaushal | Samrat Roy Choudhury

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Construction and validation of a novel SUMOylation-related lncRNAs signature for predicting the prognosis, tumor immune microenvironment, and therapeutic sensitivity of lung adenocarcinoma

March 2025

Jie Cai | Weizhong Ruan | Zida Wang | Gongzhe Liu | Bei Yang | Hao Wang | Deping Zhao | Chang Chen | Xiaogang Zhao

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SNORD3B-2 promotes endometrial carcinoma progression by 2′-O-methylation modification of PLK1 and regulating RAB17 alternative splice

March 2025

Xi Chen | Yuping Du | Bumin Xie | Qianhui Li | Yumeng Ji | Yang Han | Xiujie Sheng | Shuo Chen | Yang Zhao

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De novo missense variants of UNC13A are implicated in epileptic encephalopathies and neurodevelopmental disorders

March 2025

Ke Su | Yu Ma | Mingshan Zhou | Yihan Liu | Chengjie Li | Yonghui Jiang | Qihui Wu | Gang Peng | Yi Wang | Shaohua Fan

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