Machine learning for polyphenol-based materials
June 2024
Polyphenol-based materials, primarily composed of polyphenolic compounds, have attracted considerable attention due to their unique chemical structures and biological activities. However, there are...
Share article
Nanoparticles (NPs)-mediated targeted regulation of redox homeostasis for effective cancer therapy
June 2024
Although characterized by high reactive oxygen species (ROS) generation, cancer cells maintain redox homeostasis to avoid severe damage (e.g., DNA, protein, and plasma membrane dysfunction) and facilitate...
Share article
Enhancing bone regeneration with a novel bioactive glass-functionalized polyetheretherketone scaffold by regulating the immune microenvironment
March 2024
Polyetheretherketone (PEEK) has become a promising material for bone engineering due to its excellent mechanical properties, radiolucency and chemical resistance. However, its inherent bioinertness...
Share article
Real-time actuation of a dielectric elastomer actuator neuroprosthesis for facial paralysis
March 2024
Facial paralysis is a highly burdening condition, resulting in a patient's inability to move his mimic musculature on one or both sides of his face. This condition compromises the patient's communication...
Share article
Potentiating sorafenib efficacy against hepatocellular carcinoma via a carrier-free nanomedicine of artesunate prodrug
March 2024
Sorafenib is a first-line drug for liver cancer treatment, but its clinical efficacy is still limited by drawbacks such as drug tolerance, toxic effects, and low bioavailability. Therefore, it is urgent...
Share article
Recent advances in three-dimensional printing in cardiovascular devices: Bench and bedside applications
March 2024
Three-dimensional (3D) printing is emerging as an innovative technology, which is widely used in cardiovascular disease at bench and bedside. During the last decade, with the development of 3D printing...
Share article
Anti-fouling coatings for blood-contacting devices
March 2024
Blood-contacting medical devices, such as vascular stents, intravascular catheters, and artificial heart valves, frequently encounter complications in clinical practice, including thrombosis, inflammatory...
Share article
The marine natural product trichobotrysin B inhibits proliferation and promotes apoptosis of human glioma cells via the IL-6-mediated STAT3/JAK signaling pathway
March 2024
Glioma is the most common malignant tumor of the central nervous system. Drug-assisted chemotherapy is an important adjuvant treatment post-surgery, but currently, effective chemotherapy drugs for glioma...
Share article
A detailed protocol for cell force measurement by traction force microscopy
March 2024
Cellular traction forces (CTFs) are generated by adherent cells and involved in regulating migration, morphology, and homeostasis. Accurate measurement of CTFs is crucial for understanding fundamental...
Share article
Smartphone-based polydiacetylene colorimetric sensor for point-of-care diagnosis of bacterial infections
March 2024
The rapid progress in point-of-care testing (POCT) has become a promising decentralized patient-centered approach for the control of infectious diseases, especially in resource-limited settings. POCT...
Share article
Optimising degradation and mechanical performance of additively manufactured biodegradable Fe–Mn scaffolds using design strategies based on triply periodic minimal surfaces
March 2024
Additively manufactured lattices based on triply periodic minimal surfaces (TPMS) have attracted significant research interest from the medical industry due to their good mechanical and biomorphic properties....
Share article
Optical nanoprobes in biomedical diagnosis assays: Recent progress
March 2024
Biomedical assays based on optical nanoprobes play an important role in human health. Optical nanoprobes, the nanomaterials with special optical properties, are widely utilized in biomedical assays....
Share article
Bioactive carbon dots for tissue engineering applications
March 2024
Carbon dots (CDs) are carbon-based zero-dimensional nanomaterials with characteristic sizes of less than 10 nm. Recently, bioactive CDs have made remarkable achievements in wound healing, bone and...
Share article
Magnetosurgery: Principles, design, and applications
March 2024
Magnetosurgery, the guidance or actuation of surgical instruments during operations using magnetic forces, has become a global trend in minimally invasive surgeries performed remotely. Despite the promise...
Share article
Hydrogel wound dressings containing bioactive compounds originated from traditional Chinese herbs: A review
March 2024
Various factors can cause skin defects, resulting in the loss of physiological functions and even death due to severe concurrent infection. Dressings are often clinically used to fully cover the wounds...
Share article
Octopus -inspired gelatin-methacrylate scaffolds loaded with hBMSC-derived exosomes promote wound healing by regulating macrophage polarization
March 2024
Excessive local movement and inflammation are common problems in the process of wound repair, which lead to failure of later repair. In order to solve this problem, inspired by the octopus sucker structure,...
Share article
Phospholipid-based nanodrill technology for enhanced intracellular delivery of nano-sized cargos
2023
Nanosized drug delivery systems typically enter the cell via endocytosis. However, a significant amount of the endocytosed cargo cannot effectively escape from the endosome, resulting in drug degradation....
Share article
Tube-shaped nanostructures for enhancing resin-based dental materials: A landscape of evidence and research advancement
2023
With the advent of nanotechnology, incorporating nanoscale fillers in dental resins seems promising to improve therapeutic features and provide more excellent physicochemical properties for dental materials....
Share article
In situ electrospun aloe-nanofiber membrane for chronic wound healing
2023
Alleviating excessive inflammation while accelerating chronic wound healing to prevent wound infection has remained challenging, especially during the coronavirus disease 2019 (COVID-19) pandemic caused...
Share article
Structurally optimized electrospun scaffold for biomaterial-controlled synergistic enhancement of defective bone healing
2023
Bone repair processes are tightly affected by fiber topographies of scaffolds and can be promoted by coupling with chemotactic and/or angiogenic molecules. Here, we developed polycaprolactone (PCL)...
Share article
Biofabrication of natural Au/bacterial cellulose hydrogel for bone tissue regeneration via in-situ fermentation
2023
Bacterial cellulose (BC) possesses the desirable properties of biocompatibility, high porosity, high surface area and noticeable mechanical strength as a scaffold in bone tissue engineering. However,...
Share article
Core-shell nanostructures for improving dental restorative materials: A scoping review of composition, methods, and outcome
2023
Dental resin adhesives and composites are the most prevailing dental restorative materials used to treat cavitated tooth decay. These materials are challenged inside the mouth by bacterial acid attack,...
Share article
Promotion of wound healing by a thermosensitive and sprayable hydrogel with nanozyme activity and anti-inflammatory properties
2023
The rapid healing of wounds requires strategies that relieve oxidative stress resulting from overloaded free radicals and which promote angiogenesis, collagen deposition, and re-epithelialization of...
Share article
Immunomodulation-based development engineering for advancing metal soft tissue implants
2023
Metal materials have been widely applied clinically due to their superior mechanical properties. However, the integration of metallic implants with surrounding soft tissue remains challenging and may...
Share article