Soft bioelectronics for the diagnosis and treatment of heart diseases
March 2025
Soft bioelectronics is a type of innovative technology that creates electronic devices of organic or inorganic materials on flexible/ductile substrate, holding tremendous promise for the diagnosis and...
Share article
Ultrasound-activated mechanochemical reactions for controllable biomedical applications
December 2024
Intramolecular bonds in small organic molecules, macromolecules, and organic-inorganic hybrids are broken or formed by ultrasound-activated mechanical force that can be applied with spatial and temporal...
Share article
Programming-via-spinning: Electrospun shape memory polymer fibers with simultaneous fabrication and programming
December 2024
Porous shape memory polymer (SMP) scaffolds are promising ‘smart’ materials for potential use in a wide range of biomedical applications. Electrospinning provides an approach to produce fibrous SMP...
Share article
Progress of smart material in the repair of intervertebral disc degeneration
December 2024
Intervertebral disc degeneration (IVDD) is a prevalent condition leading to back and leg pain as well as chronic disability. It refers to the degeneration of intervertebral disc structure, including...
Share article
Bioactive MXene hydrogel promotes structural and functional regeneration of skeletal muscle through improving autophagy and muscle innervation
December 2024
Complete skeletal muscle regeneration after traumatic injuries remains a challenge due to impaired regenerative capability and dysregulated microenvironments. Autophagy plays a crucial role in the muscle...
Share article
Nanobody-as versatile tool emerging in autoimmune diseases
December 2024
Nanobody (Nb) is derived from the variable domain of heavy-chain antibody (HCAb), naturally displaying notable properties like nano-scale size, exceptional stability, high specificity, low immunogenicity,...
Share article
Current situation and challenges of polyhydroxyalkanoates-derived nanocarriers for cancer therapy
December 2024
The sustained-release system for chemotherapeutic drugs or photosensitizer based on drug-loaded biopolyester nanocarriers can effectively reduce the overall dosage and frequency of administration, thereby...
Share article
Bioactive matters based on natural product for cardiovascular diseases
December 2024
Natural products are valuable sources of bioactive compounds for drug development. It is useful to explore natural products to treat cardiovascular disease. This review provides an overview of the natural...
Share article
Biomimetic 3D printing of photocrosslinkable biodegradable elastomers-modified hybrid scaffolds as instructive platforms for bone tissue regeneration
Available online 18 December 2024
3D printing is regarded as an ideal method for large-scale bone defect repair. A rapid curing rate and strong mechanical properties throughout the product's shelf life are key development goals in 3D-printed...
Share article
Construction of an uricase/catalase/curcumin-co-loaded drug delivery system and its effect on hyper-uric acid-induced kidney injury
September 2024
Hyper-uric acid (UA)-induced kidney injury (HAKI) is caused by the deposition of excess blood UA into the kidneys. We confined molecules of uricase (URI), catalase (CAT), and curcumin (Cur) to a single...
Share article
Smart materials in medicine 5th anniversary
September 2024
Share article
Organic-inorganic nHA-Gelatin/Alginate high strength macroporous cryogel promotes bone regeneration
September 2024
Macroporous cryogel has the advantages of nutrient exchange and cell growth, and is an ideal material for tissue regeneration. In order to strengthen the machenical properties of cryogel for the widely...
Share article
Advances in smart biomaterials that modulate the bone microenvironment to promote bone defect repair in diabetes mellitus
September 2024
Diabetes mellitus (DM) is a chronic metabolic disorder that can affect the balance of bone metabolism and bone microenvironment, leading to impaired fracture healing. There are several underlying mechanisms...
Share article
Pulmonary delivery of bioadhesive nanoparticles for ALI improvement and ARDS prevention with a single-dose administration
September 2024
Acute respiratory distress syndrome (ARDS), a severe form of acute lung injury (ALI), is the major cause of intensive care unit death worldwide. ALI/ARDS is a common condition characterized by a storm...
Share article
Mitochondrial targeted prodrug nanoparticles for chemo-photodynamic combinational tumour therapy
September 2024
Prodrug nanoparticles have been explored as an effective means for drug delivery because of controlled drug release in a stimulus-responsive manner. Organellar-targeted drug delivery could enhance the...
Share article
Advances of surface modification to alleviate oxidative stress-induced valve degeneration
September 2024
Valvular heart disease (VHD) is a significant public health threat, with heart valve replacement surgery being the standard treatment for severe cases. Despite of advancements in artificial heart valves,...
Share article
Externally triggered drug delivery systems
September 2024
Externally triggered drug delivery systems empower patients or healthcare providers to utilize external stimuli to initiate drug release from implanted systems. This approach holds significant potential...
Share article
Magnesium-based bioceramic-enhanced composites fabricated via friction stir processing
September 2024
Improving the degradation performance and enhancing the biocompatibility are the main challenges of Mg-based biodegradable implants. In this study, a nano-hydroxyapatite-enhanced (nHA) Mg matrix composite...
Share article
The state-of-the-art therapeutic paradigms against sepsis
September 2024
Sepsis frequently leads to life-threatening organ failure due to an in appropriate response by the body to bacterial, viral, and fungal infections. In recent years, there has been an increasing interest...
Share article
Artificial intelligence (AI) meets biomaterials and biomedicine
June 2024
With the rapid progress of information technology and life sciences, artificial intelligence (AI) technology has substantially changed the way in many areas of biomaterials and biomedicine, including...
Share article
Hydrogel-fiber-mesh-based 3D cell cultures: A new method for studying pituitary tumors
June 2024
Acromegaly is a challenging medical condition that arises from the excessive production of growth hormones and the insulin-like growth factor 1 in the pituitary gland. While surgery is the primary treatment...
Share article
A magnetic-enhanced FRET biosensor for simultaneous detection of multiple antibodies
June 2024
Accurate, rapid and sensitive detection of specific immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies in human samples is crucial for preventing and assessing pandemics, especially in the...
Share article
Inhalable nanomedicine for lung cancer treatment
June 2024
Lung cancer has surpassed other types of cancer to become the primary cause of cancer-related deaths. Surgery stands as the foremost clinical treatment strategy available for tackling this condition,...
Share article
Heparin-loaded hierarchical fiber/microsphere scaffolds for anti-inflammatory and promoting wound healing
June 2024
Chronic non-healing wounds induced by oxidative stress and inflammation can activate inflammatory cells and produce large amounts of inflammatory mediators, which fail to maintain homeostasis in the...
Share article
Recent progress of 3D printed vascularized tissues and organs
June 2024
Since the need for vascular networks to supply oxygen and nutrients while expelling metabolic waste, most cells can only survive within 200 μm of blood vessels; thus, the construction of well-developed...
Share article
