Drug designing and synthesis of novel diphenyl 1,3,4 oxadiazoles: Multi-targeted therapeutics for the treatment of malassezia-induced dandruff
Available online 22 April 2025
This article explores the potential of novel Diphenyl 1,3,4-oxadiazole as an anti-dandruff agent against Malassezia species. Mono-, di-, and triglycerides generated from human skin sebum are broken...
Share article
Exploring the mechanism of action of tolvaptan in the treatment of cor pulmonale pulmonary hypertension using network pharmacology and animal-based experiments
Available online 21 April 2025
Cor pulmonale is a heart disease caused primarily by pulmonary hypertension (PH) due to vascular lesions of the broncho-pulmonary tissue or pulmonary arteries. PH is a central link and prerequisite...
Share article
Mechanism of Yangxuetongmai Decoction in treating essential hypotension: A network pharmacology, Mendelian randomization and molecular docking strategy analysis
Available online 21 April 2025
To investigate the mechanisms of Yangxuetongmai Decoction in treating essential hypotension using network pharmacology, Mendelian randomization, and molecular docking strategy analysis....
Share article
Simulation, 3D-QSAR, molecular docking and pharmacophore mapping studies on indole derivatives as aromatase inhibitors
Available online 21 April 2025
Aromatase inhibition is a proven strategy for the treatment of ER+ breast cancer, which accounts for more than 70 % of cases of breast cancer. Indole-based aromatase inhibitors have changed the dynamics...
Share article
Exploration of the mechanism of quercetin against GDM based on network pharmacology and molecular docking
Available online 21 April 2025
Gestational diabetes mellitus (GDM) is among the most common complications in pregnancy, endangering both the mother and the fetus. Quercetin demonstrated anti-hyperglycemic effects. Our research aimed...
Share article
Chromium chelated carrageenan: An investigation of physicochemical properties, toxicity, and antimicrobial potential through a computational and experimental approach
Available online 21 April 2025
Carrageenan (car-) was extracted from Eucheuma isoforme and chelated with chromium ions (Cr³⁺) to evaluate its physicochemical properties, antimicrobial potential, and toxicity through both experimental...
Share article