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ISSN: 2588-9338
CN: 10-1796/Q
p-ISSN: 2097-2105

Evolutionary analysis of Omicron variant BF.7 and BA.5.2 pandemic in China

On December 7, 2022, China adjusted public health control measures, there have been widespread of SARS-CoV-2 infections in Chinese mainland. As the number of infected people increased, the mutation...

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Synthetic biology: Recent progress, biosafety and biosecurity concerns, and possible solutions

Synthetic biology is a new interdisciplinary research area that uses engineering principles as guidelines for biological investigation. With research goals to modify existing biological systems or to...

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Biosafety and biosecurity in the era of biotechnology: The Middle East region

Biotechnology became a paradigm-shifting science among all subfields of biology. The benefits of biotechnology have reached many practical fields, whether human health, animal, and/or agricultural....

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Optimization of cryopreservation of pathogenic microbial strains

The preservation of pathogenic microbial strains is of great significance for basic research in microbiology and utilization of microbial resources. Appropriate preservation methods can maintain high...

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Biosafety and biosecurity

With the profound changes in the international security situation, the progression of globalization, and the continuous advancement of biotechnology, the risks and challenges posed by major infectious...

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A brief history of the development of infectious disease prevention, control, and biosafety programs in China

Safety of human beings has always been threatened by infectious diseases. In the process of fighting them, humans have continuously explored and researched the pathogens, transmission routes, prevention,...

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Mosquito-borne diseases: Assessing risk and strategies to control their spread in the Middle East

Mosquito-borne diseases (MBDs), like malaria and mosquito-borne viruses (MBVs), have caused the deaths of millions of people. Their threat resides in the variety of transmission modes that they possess,...

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Biosafety laboratory risk assessment

Biosafety laboratory risk assessment is a dynamic and systematic work. The scope of the assessment involves evaluation of pathogenic microbial hazards, experimental activities, facilities and equipment,...

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Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance

How to ensure the safe, effective, and ethical use of emerging biotechnologies, such as clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing, is a global challenge....

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Challenges and recent progress in the governance of biosecurity risks in the era of synthetic biology

Considerable progress has been achieved in basic research and the biotechnological application of biological sciences in recent years. Synthetic biology integrates systems biology, engineering, computer...

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Laboratory information management system for biosafety laboratory: Safety and efficiency

Laboratory information management system (LIMS) has been widely used to facilitate laboratory activities. However, the current LIMSs do not contain functions to improve the safety of laboratory work,...

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Ethical framework on risk governance of synthetic biology

Synthetic biology is an emerging multidisciplinary field that aims to design and construct new biological systems not found in nature. Whereas synthetic biology may yield tremendous benefits, it may...

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A targeted vaccination strategy: Integrating vaccines into biosafety, biosecurity, and one health initiatives

Vaccination has saved millions of lives and is regarded as one of modern medicine’s most important successes. Effective vaccination programs should be based on risk assessment that considers demographic...

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Regulation of toxins and bioregulators under the Chemical Weapons Convention and the Biological and Toxin Weapons Convention

In this paper we highlight how the apparent double coverage of toxins and bioregulators by both the Biological and Toxin Weapons Convention (BTWC) and the Chemical Weapons Convention (CWC) in fact masks...

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Development and assessment of cutting-edge biotechnologies

The emergence of advanced biotechnologies has intensified in recent years. The rapid development of these biotechnologies has had a wide and profound impact globally, with the majority on the frontier...

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Adherence to biosafety and biosecurity protocols: An assessment of biomedical and veterinary laboratories in Benin

Diagnostic laboratories play a crucial role in surveillance and epidemic preparedness. However, gaps in adherence to biosecurity and biosafety protocols in managing, isolating, storing, and disposing...

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A One Health strategy for emerging infectious diseases based on the COVID-19 outbreak

Coronavirus disease 2019 (COVID-19) is as an emerging infectious disease (EID) that has caused the worst public health catastrophe of the 21st century thus far. In terms of impact, the COVID-19 pandemic...

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High-containment facilities and the role they play in global health security

Biological threats, whether naturally occurring or accidentally or deliberately released, have the potential to endanger lives and disrupt economies worldwide. Thus, high-containment protective measures...

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Applications of the One Health concept: Current status in the Middle East

•The concept of One Health is one of the most important topics of modern health that the world seeks to apply.•Manitaining and enhancing human, plant, and animal health from the aspect of One Health.•The...

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Development of and prospects for the biological weapons convention

Biological weapons are used in wars to wound or kill people or animals and destroy crops with pathogenic microorganisms such as bacteria and viruses, as well as toxins and other biologically active...

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The potential epidemic threat of Ebola virus and the development of a preventive vaccine

Ebola virus (EBOV) is classified as a category A pathogen as it causes viral hemorrhagic fever, one of the most-deadly virus-related diseases. Since its discovery in 1976, EBOV has caused a number of...

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A review of the risk of cholera outbreaks and urbanization in sub-Saharan Africa

The sub-Saharan region of Africa is rapidly urbanizing, that has consequently spurred the development of specific challenges in terms of access to basic services and sanitation. Thus, exposure to waterborne...

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Current status and future challenges of high-level biosafety laboratories in China

High-level biosafety laboratories are safe and secure platforms which integrate reliable containment, well-trained personnel, and specific biosafety manuals and practices to protect researchers from...

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Public awareness, participation and attitude toward the national biosafety framework and genetically modified organisms in Ghana

Public engagement in the development, promotion, and utilization of innovation is an important part of any biosafety decision-making process. Under the Cartagena Protocol on Biosafety, the public is...

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“Mutation blacklist” and “mutation whitelist” of SARS-CoV-2

Over the past two years, scientists throughout the world have completed more than 6 million SARS-CoV-2 genome sequences. Today, the number of SARS-CoV-2 genomes exceeds the total number of all other...

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