Evolutionary analysis of Omicron variant BF.7 and BA.5.2 pandemic in China
March 2023
On December 7, 2022, China adjusted public health control measures, there have been widespread of SARS-CoV-2 infections in Chinese mainland. As the number of infected people increased, the mutation...
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Mosquito-borne diseases: Assessing risk and strategies to control their spread in the Middle East
March 2024
Mosquito-borne diseases (MBDs), like malaria and mosquito-borne viruses (MBVs), have caused the deaths of millions of people. Their threat resides in the variety of transmission modes that they possess,...
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Biosafety and biosecurity in the era of biotechnology: The Middle East region
December 2022
Biotechnology became a paradigm-shifting science among all subfields of biology. The benefits of biotechnology have reached many practical fields, whether human health, animal, and/or agricultural....
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Development and assessment of cutting-edge biotechnologies
March 2024
The emergence of advanced biotechnologies has intensified in recent years. The rapid development of these biotechnologies has had a wide and profound impact globally, with the majority on the frontier...
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Synthetic biology: Recent progress, biosafety and biosecurity concerns, and possible solutions
March 2019
Synthetic biology is a new interdisciplinary research area that uses engineering principles as guidelines for biological investigation. With research goals to modify existing biological systems or to...
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Regulation of toxins and bioregulators under the Chemical Weapons Convention and the Biological and Toxin Weapons Convention
June 2024
In this paper we highlight how the apparent double coverage of toxins and bioregulators by both the Biological and Toxin Weapons Convention (BTWC) and the Chemical Weapons Convention (CWC) in fact masks...
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Optimization of cryopreservation of pathogenic microbial strains
December 2020
The preservation of pathogenic microbial strains is of great significance for basic research in microbiology and utilization of microbial resources. Appropriate preservation methods can maintain high...
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Biosafety and biosecurity
March 2019
With the profound changes in the international security situation, the progression of globalization, and the continuous advancement of biotechnology, the risks and challenges posed by major infectious...
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A brief history of the development of infectious disease prevention, control, and biosafety programs in China
March 2020
Safety of human beings has always been threatened by infectious diseases. In the process of fighting them, humans have continuously explored and researched the pathogens, transmission routes, prevention,...
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Rethinking biosecurity in the 21st century: An enhanced role for civil society
September 2023
In this paper, we briefly discuss the historical issues concerning the Biological and Toxin Weapons Convention (BTWC) and analyse the current situation after the COVID-19 pandemic with emphasis on the...
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COVID’s future: Viral multi-lineage evolution and the dynamics of small epidemic waves without seasonality in COVID-19
September 2023
Since its emergence, SARS-CoV-2 virus, the causative agent of COVID-19, has undergone over three years of evolutionary changes. Throughout this evolutionary process, multiple variants, such as Alpha,...
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Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
March 2023
How to ensure the safe, effective, and ethical use of emerging biotechnologies, such as clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing, is a global challenge....
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Ethical framework on risk governance of synthetic biology
June 2023
Synthetic biology is an emerging multidisciplinary field that aims to design and construct new biological systems not found in nature. Whereas synthetic biology may yield tremendous benefits, it may...
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Biosafety laboratory risk assessment
September 2019
Biosafety laboratory risk assessment is a dynamic and systematic work. The scope of the assessment involves evaluation of pathogenic microbial hazards, experimental activities, facilities and equipment,...
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A targeted vaccination strategy: Integrating vaccines into biosafety, biosecurity, and one health initiatives
March 2025
Vaccination has saved millions of lives and is regarded as one of modern medicine’s most important successes. Effective vaccination programs should be based on risk assessment that considers demographic...
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Challenges and recent progress in the governance of biosecurity risks in the era of synthetic biology
June 2022
Considerable progress has been achieved in basic research and the biotechnological application of biological sciences in recent years. Synthetic biology integrates systems biology, engineering, computer...
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Laboratory information management system for biosafety laboratory: Safety and efficiency
June 2021
Laboratory information management system (LIMS) has been widely used to facilitate laboratory activities. However, the current LIMSs do not contain functions to improve the safety of laboratory work,...
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Dual-use oversight: Is the scientific community fit for Purpose? What should be done if it is not?
December 2023
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Preparation of ZnO nanoparticles from Juglans regia dry husk extract for biomedical applications
March 2025
The worldwide problem of antibiotic resistance threatens public health, necessitating the search for antimicrobial agents that are not only effective against antibiotic-resistant bacteria but also harmless...
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Overview and prospects of food biosafety
December 2022
Biosafety issues have become a major threat to the health of humans, animals, and ecosystems worldwide. As problems with food production and the food supply chain have become of greater concern to consumers,...
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The potential epidemic threat of Ebola virus and the development of a preventive vaccine
June 2023
Ebola virus (EBOV) is classified as a category A pathogen as it causes viral hemorrhagic fever, one of the most-deadly virus-related diseases. Since its discovery in 1976, EBOV has caused a number of...
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Development of and prospects for the biological weapons convention
June 2022
Biological weapons are used in wars to wound or kill people or animals and destroy crops with pathogenic microorganisms such as bacteria and viruses, as well as toxins and other biologically active...
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“Mutation blacklist” and “mutation whitelist” of SARS-CoV-2
December 2022
Over the past two years, scientists throughout the world have completed more than 6 million SARS-CoV-2 genome sequences. Today, the number of SARS-CoV-2 genomes exceeds the total number of all other...
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Applications of the One Health concept: Current status in the Middle East
March 2023
•The concept of One Health is one of the most important topics of modern health that the world seeks to apply.•Manitaining and enhancing human, plant, and animal health from the aspect of One Health.•The...
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Assessment of biosafety implementation in clinical diagnostic laboratories in Pakistan during the COVID-19 pandemic
June 2022
Laboratory diagnostic capacity is crucial for an optimal national response to a public health emergency such as the COVID-19 pandemic. Preventing laboratory-acquired infections and the loss of critical...
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