Comparative study of colistin methanesulfonate and colistin sulfate/polymyxin B in the treatment of ceftazidime-avibactam resistant Gram-negative bacilli infections
October 2024
To evaluate the clinical efficacy of different species of polymyxin drugs in the treatment of Carbapenem-Resistant Gram-negative bacilli (CR-GNB) resistant to ceftazidime-avibactam (CZA)....
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Cancer drug resistance is a serious threat in Bangladesh
October 2024
Cancer drug resistance is a serious issue in Bangladesh that must be addressed with effective solutions. The growth of resistant bacterial strains, inappropriate use of antimicrobials, and inadequate...
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A comprehensive review on the chemical composition and pharmacological activities of ACACIAARABICA
October 2024
Since the dawn of time, people have used herbal medications to both prevent and treat a variety of illnesses. Numerous illnesses, including diabetes, skin conditions, and most seriously cancer, have...
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Mimusops elengi: A comprehensive review
October 2024
Mimusops elengi, a widely distributed tree species in tropical regions, has been used for centuries in traditional medicine due to its numerous therapeutic properties. In this study, we conducted a...
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Comprehensive review on modern techniques of granulation in pharmaceutical solid dosage forms
October 2024
This comprehensive review explores modern granulation techniques in pharmaceutical dosage forms along with conventional methods, focusing on dry granulation and wet granulation. Dry granulation techniques,...
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Current approaches in nanostructured biomaterials in treatment of leiomyosarcoma
October 2024
One form of uncommon cancer that develops in the smooth muscles is called leiomyosarcoma, or LMS. The body's hollow organs, such as the stomach, bladder, intestines, and blood vessels, contain smooth...
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Suspected undeclared use of generative artificial intelligence
October 2024
In a recent article in Intelligent Pharmacy, a portion of the text appears to have been generated by a generative artificial intelligence (AI) system. The usage of AI is not documented in the article....
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Advancements in Transdermal Drug Delivery Systems: Enhancing Medicine with Pain-Free and Controlled Drug Release
Available online 11 October 2024
Transdermal Drug Delivery Systems (TDDSs) provide controlled and prolonged drug release, enhance patient compliance, reduce gastrointestinal side effects, and improve drug stability. By delivering medication...
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Alkaloids Unveiled: A Comprehensive Analysis of Novel Therapeutic Properties, Mechanisms, and Plant-Based Innovations
Available online 27 September 2024
Alkaloids, naturally occurring compounds in a diverse range of plant species (Coffea spp., Erythroxylum coca, Cinchona spp. etc.), hold vast potential for biological, medicinal, and pharmacological...
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ENSURING DATA INTEGRITY: BEST PRACTICES AND STRATEGIES IN PHARMACEUTICAL INDUSTRY
Available online 26 September 2024
The objective of this article is to examine the challenges and best strategies for incorporating data integrity in the pharmaceutical industry to ensure regulatory compliance. It highlights the importance...
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Phytochemical Profiling, FT-IR Spectroscopy, and Antioxidant Evaluation of Select Lamiaceae Species
Available online 26 September 2024
The present study aimed to conduct a preliminary phytochemical analysis of aqueous, ethanol, and hexane leaf extracts from Anisomeles malabarica (L.) R.Br. ex Sims, Leucas aspera (Willd.) Link., Ocimum...
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Nanostructured lipid carriers as a drug delivery system: A comprehensive review with therapeutic applications
Available online 23 September 2024
Recent advances in nanotechnology have enabled significant developments in health through innovative drug delivery systems. Nanostructured lipid carriers (NLCs) have emerged as a key technology in this...
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Nanoliposome as a carrier for topical delivery of oxymetazoline hydrochloride: In-vitro assessment and in-vivo anti-inflammatory potential
Available online 22 September 2024
The present investigation on nanoliposome infused with oxymetazoline hydrochloride was fabricated with phosphatidylcholine and cholesterol to effectively deliver the drug to the skin. Oxymetazoline...
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Stratification of cephalosporins based on physicochemical and pharmacokinetic variables using multivariate statistical tools
Available online 18 September 2024
Cephalosporins, a class of beta-lactam antibiotics, are commonly used in medical practice. However, their potential advantages, based on physicochemical and pharmacokinetic variables, are often overlooked....
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Optimization of Microwave-Assisted Green Synthesis of Zinc oxide nanoparticles Using Ocimum americanum and Euphorbia hirta Extracts: In Vitro Evaluation of Antioxidant, Anti-inflammatory, Antibacterial, Cytotoxicity, and Wound Healing Properties
Available online 11 September 2024
This investigation optimized the microwave-assisted green synthesis of zinc oxide nanoparticles utilizing Ocimum americanum and Euphorbia hirta extracts for enhanced wound healing applications. The...
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Enhancing Monoclonal Antibodies with Natural Products: Mechanisms and Applications
Available online 5 September 2024
Monoclonal antibodies (mAbs) have revolutionized therapeutic strategies across a broad spectrum of diseases, yet their efficacy remains constrained by challenges such as suboptimal tumor penetration...
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Trends in Research on AI-aided drug discovery from 2009 to 2023: a 15-year Bibliometric Analysis
Available online 4 September 2024
In recent years, the rapid advancement of artificial intelligence technology has brought opportunities for the acceleration and improvement of the drug discovery process by aiding in all stages of drug...
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The fermented milk can be a natural ally against obesity? Investigation of bovine milk fermentation by Lacticaseibacillus casei LBC 237, screening, and In silico predictions of bioactive peptides for obesity control
August 2024
The increasing quest for therapeutic alternatives in treating non-communicable chronic diseases like obesity has propelled research into bioactive peptides, with a particular focus on milk due to its...
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Rosmarinic acid: Potential antiviral agent against dengue virus - In silico evaluation
August 2024
A number of dengue viruses can seriously impact public health, and their spread has long been a concern. The development and administration of antiviral drugs have played a crucial role in combating...
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Unveiling the intricacies of phytate antinutrients in millets and their therapeutic implications in breast cancer
August 2024
Breast cancer remains a significant global health concern, necessitating the exploration of novel preventive and therapeutic strategies. Dietary interventions have gained substantial attention due to...
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QSAR application of natural therapeutics inhibitors against Alzheimer's disease through in-silico virtual-screening, docking-simulation, molecular dynamics, and pharmacokinetic prediction analysis
August 2024
Alzheimer's disease (AD) is a brain disorder that is known to be one of the deadliest diseases affecting humanity, especially adults from the age of sixty (60) years and above. It mostly affects thinking...
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Telmisartan-loaded liposomes: An innovative weapon against breast cancer
August 2024
This study focuses on the development of a liposomal preparation for the targeted delivery of Telmisartan in the context of breast cancer treatment. Telmisartan, a pharmaceutical agent with potential...
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