Advancements in Contemporary Pharmacological Innovation: Mechanistic Insights and Emerging Trends in Drug Discovery and Development
Available online 2 November 2024
Developing a new drug and bringing it to the market is a complex and time-consuming process that involves multiple phases of drug discovery and development. However, recent advancements in various technologies,...
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A systematic review on the effectiveness of Zingiber officinale in reducing dental caries
October 2024
According to the Global Burden of Disease Study and the World Health Organization, dental caries is one of the most prevalent oral diseases globally. It is well known that dental caries are associated...
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Comprehensive evaluation of PD-1 inhibitors marketed in China based on a Quick Guideline for drug evaluation and selection in Chinese Medical Institutions (second edition)
October 2024
To conduct a comprehensive evaluation of PD-1 inhibitors for the treatment of advanced non-small cell lung cancer on the market in China, using A Quick Guideline for Drug Evaluation and Selection in...
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AI's role in revolutionizing personalized medicine by reshaping pharmacogenomics and drug therapy
October 2024
This paper examines the transformative impact of artificial intelligence (AI) on pharmacogenomics, signaling a paradigm shift in personalized medicine. With a focus on enhancing drug response prediction...
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Computational transformation in drug discovery: A comprehensive study on molecular docking and quantitative structure activity relationship (QSAR)
October 2024
The procedure for learning and creating a new medicine is widely seen as a drawn-out and costly endeavor. Different rational strategies are considered, depending on their requirements, as potential...
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Artificial intelligence in anti-dengue drug development
October 2024
Dengue fever is a mosquito-borne illness that affects millions of people worldwide. Artificial intelligence (AI) is being employed in the battle against it. AI is being used to analyse dengue immune...
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Design of some potent non-toxic Autoimmune disorder inhibitors based on 2D-QSAR, CoMFA, molecular docking, and molecular dynamics investigations
October 2024
Current clinical research suggests that inhibitors of protein arginine deiminase 4 (PAD4), major histocompatibility complex (MHC) class II HLA-DQ-ALPHA chain, and thyrotropin receptor (or TSH receptor)...
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Pharmaceutical advances: Integrating artificial intelligence in QSAR, combinatorial and green chemistry practices
October 2024
The utilization of pharmaceuticals in medical and veterinary treatment has not only improved human and animal health but has also boosted food-production and economic welfare. However, the release of...
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Current advances in nano drug delivery system for dengue treatment and prevention
October 2024
Dengue is a most important mosquito-borne viral illnesses. The disease is caused by dengue viruses that have four serotypes: dengue 1, dengue 2, dengue 3 and dengue 4. Primary infection usually results...
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Cardioprotective potential of Rosuvastatin against isoproterenol induced cardiac dysfunction and hypertrophy in the experimental model of rodents
October 2024
Cardiovascular disease is the primary cause of mortality and morbidity, and its terminal phase is chronic heart failure. The present study aimed to examine the protective impact of rosuvastatin on isoproterenol-induced...
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A review of Vernonia cinerea L. ethno-medicinal uses and pharmacology shows that it could be a useful plant for medical purposes
October 2024
Vernonia cinerea L., also known as purple fleabane, is a plant with medicinal properties that have been traditionally used to treat respiratory infections, digestive disorders, and skin conditions....
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Sea buckthorn: A potential dietary supplement with multifaceted therapeutic activities
October 2024
Sea buckthorn (Hippophae rhamnoides L.) is a plant with various nutritional and medicinal properties. It contains vitamins, carotenoids, polyphenols, fatty acids, and phytosterols, which have antioxidant,...
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Role of IOT in healthcare: Applications, security & privacy concerns
October 2024
Employing the Internet of Things (IoT) in healthcare provides many advantages for patient monitoring and analysis of the patient's health with the help of generated data. The basic role of IoT in healthcare...
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Comparative study of colistin methanesulfonate and colistin sulfate/polymyxin B in the treatment of ceftazidime-avibactam resistant Gram-negative bacilli infections
October 2024
To evaluate the clinical efficacy of different species of polymyxin drugs in the treatment of Carbapenem-Resistant Gram-negative bacilli (CR-GNB) resistant to ceftazidime-avibactam (CZA)....
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Cancer drug resistance is a serious threat in Bangladesh
October 2024
Cancer drug resistance is a serious issue in Bangladesh that must be addressed with effective solutions. The growth of resistant bacterial strains, inappropriate use of antimicrobials, and inadequate...
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A comprehensive review on the chemical composition and pharmacological activities of ACACIAARABICA
October 2024
Since the dawn of time, people have used herbal medications to both prevent and treat a variety of illnesses. Numerous illnesses, including diabetes, skin conditions, and most seriously cancer, have...
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Mimusops elengi: A comprehensive review
October 2024
Mimusops elengi, a widely distributed tree species in tropical regions, has been used for centuries in traditional medicine due to its numerous therapeutic properties. In this study, we conducted a...
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Comprehensive review on modern techniques of granulation in pharmaceutical solid dosage forms
October 2024
This comprehensive review explores modern granulation techniques in pharmaceutical dosage forms along with conventional methods, focusing on dry granulation and wet granulation. Dry granulation techniques,...
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Current approaches in nanostructured biomaterials in treatment of leiomyosarcoma
October 2024
One form of uncommon cancer that develops in the smooth muscles is called leiomyosarcoma, or LMS. The body's hollow organs, such as the stomach, bladder, intestines, and blood vessels, contain smooth...
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Suspected undeclared use of generative artificial intelligence
October 2024
In a recent article in Intelligent Pharmacy, a portion of the text appears to have been generated by a generative artificial intelligence (AI) system. The usage of AI is not documented in the article....
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Advancements in Transdermal Drug Delivery Systems: Enhancing Medicine with Pain-Free and Controlled Drug Release
Available online 11 October 2024
Transdermal Drug Delivery Systems (TDDSs) provide controlled and prolonged drug release, enhance patient compliance, reduce gastrointestinal side effects, and improve drug stability. By delivering medication...
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Alkaloids Unveiled: A Comprehensive Analysis of Novel Therapeutic Properties, Mechanisms, and Plant-Based Innovations
Available online 27 September 2024
Alkaloids, naturally occurring compounds in a diverse range of plant species (Coffea spp., Erythroxylum coca, Cinchona spp. etc.), hold vast potential for biological, medicinal, and pharmacological...
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ENSURING DATA INTEGRITY: BEST PRACTICES AND STRATEGIES IN PHARMACEUTICAL INDUSTRY
Available online 26 September 2024
The objective of this article is to examine the challenges and best strategies for incorporating data integrity in the pharmaceutical industry to ensure regulatory compliance. It highlights the importance...
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Phytochemical Profiling, FT-IR Spectroscopy, and Antioxidant Evaluation of Select Lamiaceae Species
Available online 26 September 2024
The present study aimed to conduct a preliminary phytochemical analysis of aqueous, ethanol, and hexane leaf extracts from Anisomeles malabarica (L.) R.Br. ex Sims, Leucas aspera (Willd.) Link., Ocimum...
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