Multi-modal Ultrafast Sonography Microscopy (MUSM) for super-resolution imaging of cerebral vascular dynamics in a mouse model of hypertension induced by Angiotensin-II and L-NAME
Available online 16 November 2024
Hypertension is a major cause of cerebral hemorrhage. Although they are widely used in preclinical studies on cerebral hemorrhage, traditional in vivo cerebrovascular imaging techniques, such as positron...
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The evolution of brain surgery: Exploring the impact of continuum robotics
Available online 15 November 2024
Brain surgery requires at most accuracy and precision, yet current neurosurgical robots are limited in their ability to reach intracranial regions due to their rigid and inflexible nature. However,...
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Peak perihematomal edema expansion predicts poor outcome in patients with intracerebral hemorrhage
Available online 1 November 2024
Intracerebral hemorrhage (ICH) is a highly fatal and incapacitating form of stroke. Perihematomal edema (PHE) serves as a measurable radiological indicator in the progression of secondary injury and...
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Diagnostic yield of different imaging modalities in the detection rate of intracranial aneurysm remnants after microsurgical clipping – A systematic review and meta-analysis
October 2024
While the long-term durability of completely clipped intracranial aneurysms (IA) is excellent, IA with remnants poses a significant risk for future re-growth with subsequent need for long-term follow-up...
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Continuous arterial blood pressure indices and early hematoma expansion in patients with spontaneous intracerebral hemorrhage
October 2024
Blood pressure variability (BPV) and its potential association with early hematoma expansion (HE) in intracerebral hemorrhage (ICH) remains to be fully elucidated. Our study explores the potential link...
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Serum cholesterol and interleukin-10 are associated with post-intracerebral hemorrhage depression in patients with acute primary supratentorial intracerebral hemorrhage
October 2024
This study explores the correlation between serum cholesterol, interleukin-10 (IL-10), macrophage migration inhibitory factor (MIF), and post-intracerebral hemorrhage (post-ICH) depression in patients...
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Brain hemorrhages in traumatic brain injury and the excess burden conferred by anticoagulants and antiplatelets
October 2024
The objective of this study was to compare the severity of head injury in patients on an anticoagulant or antiplatelet agent and to look at the burden of these medications in patients 55 + years vs....
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Hemorrhage of the hypothalamic cavernous malformation. Clinical case of surgical treatment
October 2024
To study the clinical and neurologic symptoms and to determine the indications for surgical treatment of hypothalamic cavernous malformations....
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Effect of mesenchymal stem cell-derived exosomes on the inflammatory response after stroke
October 2024
Stroke, characterized by sudden onset and significant mortality rates, represents a critical challenge in effectively treating neuroinflammation to improve treatment efficacy. In this context, mesenchymal...
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VASP, HCLS1, MSN, and EZR: Key molecular beacons in the pathophysiology of perihematomal edema Post-Intracerebral hemorrhage
October 2024
•The study pinpoints VASP, HCLS1, MSN, and EZR as critical genes linked to tight junction integrity, playing significant roles in perihematomal edema following intracerebral hemorrhage.•Enhanced leukocyte...
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Recent trends of treatment strategies and outcomes of basal ganglia hemorrhages at a single institution
October 2024
The Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) Trial was designed to evaluate the minimally invasive trans-sulcal parafascicular surgery (MIPS) approach, a technique advertised...
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Efficacy and safety of middle meningeal artery embolization in combination with burr hole craniostomy for chronic subdural hematomas: A single-center experience
Available online 28 October 2024
Chronic subdural hematoma (CSDH) is a prevalent neurosurgical condition. The mass effect of hematoma could lead to a series of neurological dysfunctions. Surgical intervention, such as burr hole craniostomy...
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Leakage sign based on contrast-enhanced CT is a predictive marker for hematoma expansion and poor prognosis in primary brainstem hemorrhage
Available online 21 October 2024
Although hematoma expansion is a poor prognostic factor in patients with intracerebral hemorrhage (ICH), its effect on primary brainstem hemorrhage (PBSH) remains unclear. Since we previously observed...
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Prophylactic barbiturate step-down infusion therapy has similar and favorable effects in elderly and non-elderly patients with severe traumatic brain injuries
Available online 21 October 2024
With the aging population, the number of elderly patients with severe traumatic brain injury (sTBI) inevitably increases. The high mortality rate for sTBI in the elderly necessitates effective solutions....
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Non-coding RNAs in intracerebral hemorrhage: Roles, mechanisms, and therapeutic implications
Available online 10 October 2024
Intracerebral hemorrhage (ICH), which is a form of stroke triggered by the rupture of blood vessels within the brain tissue, is a leading cause of morbidity and mortality worldwide. Although significant...
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The Progressive Frontier of Aneurysmal subarachnoid Hemorrhage: Diagnosis and treatment Advances
Available online 7 September 2024
Aneurysmal subarachnoid hemorrhage affects 6 to 9 out of every 100,000 people annually, with a mortality rate of 35%. Many people suffer from long-term disabilities, often associated with cognitive...
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The use of bioinformatic analysis to study intracerebral hemorrhage
August 2024
The integration of bioinformatics analysis into intracerebral hemorrhage (ICH)research represents a paradigm shift in our approach to understanding, diagnosing, and treating this complex neurological...
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The function of astrocytes in cerebral infarction and potential therapeutic approaches
August 2024
Astrocytes, the most prevalent cells in the central nervous system, significantly contribute to the normal physiological functions of the brain. Following cerebral infarction, these astrocytes undergo...
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Increased plasma pigment epithelium-derived factor (PEDF) concentrations as a negative predictor of angiographic vasospasm after aneurysmal subarachnoid hemorrhage
August 2024
Cerebral vasospasm remains a major determinant of delayed cerebral ischemia (DCI) and poor outcomes after aneurysmal subarachnoid hemorrhage (SAH). This study was aimed to investigate if a matricellular...
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Chronic subdural hematoma: Epidemiological analysis and factors associated with hematoma size – A single center experience
August 2024
This study aims to analyze the profile of patients with chronic subdural hematoma (cSDH) and to verify the factors associated with hematoma size....
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Anterior cranial fossa dural arteriovenous fistula presenting with left basal ganglia hemorrhage: A case report
August 2024
Anterior cranial fossa dural arteriovenous fistulas (ACF-dAVFs) usually drain into the superior sagittal sinus (SSS) via the cortical veins. More rarely, the ACF-dAVF drains posteriorly into the olfactory...
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Delayed hematoma growth in a patient with thrombocytopenia
August 2024
Hematoma growth rarely occurs after 24 h in patients with intracerebral hemorrhage (ICH). Here we report a case with delayed hematoma growth caused by thrombocytopenia....
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Association between glucose-to-lymphocyte ratio and short-term mortality in critically ill subarachnoid hemorrhage patients: A retrospective cohort study
August 2024
We aimed to evaluate the association between admission glucose-to-lymphocyte ratio (GLR) and 28-day all-cause mortality in critically ill patients with non-traumatic SAH....
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Assessment of causal relationships between white matter brain imaging-derived phenotypes and CSVD-mediated Stroke: Genetic correlation and Mendelian randomization
Available online 28 August 2024
Cerebral small vessel disease (CSVD) and its associated stroke are significant contributors to mortality and long-term disability globally. Despite this, there remains a lack of established predictors...
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Activation of PARP in secondary brain injury following intracerebral haemorrhage
Available online 28 August 2024
Intracerebral hemorrhage (ICH) represents a significant health challenge due to its high mortality and severe outcomes. Poly (ADP-ribose) polymerase (PARP) is a chromatin-associated nuclear protease,...
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