Stromal vascular fraction cell therapy: A promising therapeutic method for intracerebral hemorrhage
Available online 19 February 2025
Intracerebral hemorrhage (ICH) is one of the most devastating and life-threatening forms of stroke, characterized by bleeding within the brain parenchyma. The condition is associated with a high mortality...
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Advancing brain injury treatment and neuroprotection with ligustilide: Mechanisms and therapeutic potential
Available online 18 February 2025
Brain injury is one of the leading causes of death and disability worldwide, attributable to diverse etiologies such as trauma, hypoxia, stroke, infection, or neurodegenerative diseases. Due to the...
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The role of blood lipid and triglyceride‑glucose index in intracranial aneurysms: A retrospective study
Available online 17 February 2025
The association between blood lipids and aneurysmal subarachnoid hemorrhage (aSAH) remains uncertain, with current research yielding conflicting results. Limited studies have explored the link between...
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Immune cells in intracerebral hemorrhage
Available online 17 February 2025
Intracerebral hemorrhage (ICH), the deadliest form of stroke, is characterized by bleeding into brain parenchyma and formation of hematoma. Currently, there is no treatment available for ICH. Inflammatory...
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Premorbid long-term statin use can reduce the risk of hemorrhagic transformation after ischemic stroke
Available online 17 February 2025
Hemorrhagic transformation (HT) of cerebral infarction is considered as one of the most serious complications. Increasing evidence show that statin use might reduce the neuroinflammation and even improve...
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Rupture of cerebral cavernous malformations due to cerebral venous sinus compression
Available online 17 February 2025
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Mid-term outcomes in stent-assisted coil embolization for ruptured cerebral aneurysms in the acute period: A single institution retrospective review
December 2024
The purposes of this study were to retrospectively review mid-term outcomes of stent-assisted coil embolization for acutely ruptured cerebral aneurysms, and to identify risk factors....
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Effects of glibenclamide/glyburide on stroke: Systematic review
December 2024
Glibenclamide (GBC), although traditionally used to treat type 2 diabetes mellitus, has demonstrated efficacy in preventing cerebral edema in the setting of stroke, including preserving the integrity...
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Brain Hemorrhages has specially appointed Professor Wang Yongjun from Beijing Tiantan Hospital as Honorary Editor-in-Chief
December 2024
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Assessment of causal relationships between white matter brain imaging-derived phenotypes and CSVD-mediated Stroke: Genetic correlation and Mendelian randomization
December 2024
Cerebral small vessel disease (CSVD) and its associated stroke are significant contributors to mortality and long-term disability globally. Despite this, there remains a lack of established predictors...
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Activation of PARP in secondary brain injury following intracerebral haemorrhage
December 2024
Intracerebral hemorrhage (ICH) represents a significant health challenge due to its high mortality and severe outcomes. Poly (ADP-ribose) polymerase (PARP) is a chromatin-associated nuclear protease,...
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Cerebrovascular disorders in patients with malignant tumors
December 2024
Patients with malignant tumors face an elevated risk of cerebrovascular complications, such as intratumoral hemorrhage, tumor invasion into arterial and venous sinuses, leptomeningeal infiltration,...
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Quadriparesis with bilateral anterior cerebral artery infarction following subarachnoid haemorrhage due to rupture of an anterior communicating artery aneurysm: A case report with literature review
December 2024
Anterior cerebral artery (ACA) territory infarctions are relatively rare, accounting for 0.3 % to 4.4 % of stroke cases, with bilateral occurrences being even rarer. These infarctions can lead to quadriplegia/paresis....
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Multi-modal Ultrafast Sonography Microscopy (MUSM) for super-resolution imaging of cerebral vascular dynamics in a mouse model of hypertension induced by Angiotensin-II and L-NAME
Available online 16 November 2024
Hypertension is a major cause of cerebral hemorrhage. Although they are widely used in preclinical studies on cerebral hemorrhage, traditional in vivo cerebrovascular imaging techniques, such as positron...
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The evolution of brain surgery: Exploring the impact of continuum robotics
Available online 15 November 2024
Brain surgery requires at most accuracy and precision, yet current neurosurgical robots are limited in their ability to reach intracranial regions due to their rigid and inflexible nature. However,...
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Peak perihematomal edema expansion predicts poor outcome in patients with intracerebral hemorrhage
Available online 1 November 2024
Intracerebral hemorrhage (ICH) is a highly fatal and incapacitating form of stroke. Perihematomal edema (PHE) serves as a measurable radiological indicator in the progression of secondary injury and...
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Diagnostic yield of different imaging modalities in the detection rate of intracranial aneurysm remnants after microsurgical clipping – A systematic review and meta-analysis
October 2024
While the long-term durability of completely clipped intracranial aneurysms (IA) is excellent, IA with remnants poses a significant risk for future re-growth with subsequent need for long-term follow-up...
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Continuous arterial blood pressure indices and early hematoma expansion in patients with spontaneous intracerebral hemorrhage
October 2024
Blood pressure variability (BPV) and its potential association with early hematoma expansion (HE) in intracerebral hemorrhage (ICH) remains to be fully elucidated. Our study explores the potential link...
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Serum cholesterol and interleukin-10 are associated with post-intracerebral hemorrhage depression in patients with acute primary supratentorial intracerebral hemorrhage
October 2024
This study explores the correlation between serum cholesterol, interleukin-10 (IL-10), macrophage migration inhibitory factor (MIF), and post-intracerebral hemorrhage (post-ICH) depression in patients...
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Brain hemorrhages in traumatic brain injury and the excess burden conferred by anticoagulants and antiplatelets
October 2024
The objective of this study was to compare the severity of head injury in patients on an anticoagulant or antiplatelet agent and to look at the burden of these medications in patients 55 + years vs....
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Hemorrhage of the hypothalamic cavernous malformation. Clinical case of surgical treatment
October 2024
To study the clinical and neurologic symptoms and to determine the indications for surgical treatment of hypothalamic cavernous malformations....
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Effect of mesenchymal stem cell-derived exosomes on the inflammatory response after stroke
October 2024
Stroke, characterized by sudden onset and significant mortality rates, represents a critical challenge in effectively treating neuroinflammation to improve treatment efficacy. In this context, mesenchymal...
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VASP, HCLS1, MSN, and EZR: Key molecular beacons in the pathophysiology of perihematomal edema Post-Intracerebral hemorrhage
October 2024
•The study pinpoints VASP, HCLS1, MSN, and EZR as critical genes linked to tight junction integrity, playing significant roles in perihematomal edema following intracerebral hemorrhage.•Enhanced leukocyte...
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Recent trends of treatment strategies and outcomes of basal ganglia hemorrhages at a single institution
October 2024
The Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) Trial was designed to evaluate the minimally invasive trans-sulcal parafascicular surgery (MIPS) approach, a technique advertised...
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Efficacy and safety of middle meningeal artery embolization in combination with burr hole craniostomy for chronic subdural hematomas: A single-center experience
Available online 28 October 2024
Chronic subdural hematoma (CSDH) is a prevalent neurosurgical condition. The mass effect of hematoma could lead to a series of neurological dysfunctions. Surgical intervention, such as burr hole craniostomy...
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