Antibacterial hydrogels for bacteria-infected wound treatment
March 2025
Bacteria-infected wounds are enormous clinical obstacles and cause huge burdens to patients and society. Recently, many biomaterials are designed to treat bacterial infected wounds. Among various biomaterials,...
Share article
Biomaterial-based circular RNA therapeutic strategy for repairing intervertebral disc degeneration
March 2025
Intervertebral disc degeneration (IDD) is the leading cause of low-back pain, which brings huge threaten to patients' life and workability. However, IDD's pathophysiology is still a puzzle, thus conventional...
Share article
Developing biotechnologies in organoids for liver cancer
March 2025
Organoids, three-dimensional cellular constructs, have revolutionized in vitro culture by replicating the histological and physiological functions of organs, offering a model that closely mimics physiological...
Share article
Space manufacturing of a bone tissue destined for patients on Earth?
March 2025
Space exploration is perhaps one of the most difficult tasks ever undertaken since the emergence of humankind. The International Space Station is a unique platform for advanced technology research that...
Share article
Comparative exploration of deep convolutional neural networks using real-time endoscopy images
December 2024
Until now various deep convolutional neural networks are designed and trained for the purpose of classifying different medical conditions related to the domain of gastroenterology. Most of the study...
Share article
Biomaterials that passively and actively target macrophages promote the regeneration of injured tissues
December 2024
Modulation of the immune system has gained significant attention in regenerative medicine. Although most tissues possess intrinsic self-repair capabilities, large-sized defects and complex pathological...
Share article
HFF-Net: A hybrid convolutional neural network for diabetic retinopathy screening and grading
December 2024
Diabetic Retinopathy (DR) is a leading cause of vision loss among diabetic patients, necessitating effective screening and grading for timely intervention. Regular screening significantly increases...
Share article
Electrospinning drug-loaded polycaprolactone/polycaprolactone-gelatin multi-functional bilayer nanofibers composite scaffold for postoperative wound healing of cutaneous squamous cell carcinoma
December 2024
Cutaneous squamous cell carcinoma (cSCC) tumor resection surgery poses challenges due to incomplete cancer cell removal, which increases the risk of local recurrence and micrometastasis, while large-scale...
Share article
D2 receptor antagonist raclopride regulates glutamatergic neuronal activity in the pedunculopontine nucleus in a rat model of Parkinson's disease
December 2024
Parkinson disease (PD) is defined by the loss of dopamine (DA). Changes in the pedunculopontine nucleus (PPN), particularly in local field potential (LFP), can be attributed to deficits in DA and DA...
Share article
HMS-TENet: A hierarchical multi-scale topological enhanced network based on EEG and EOG for driver vigilance estimation
December 2024
Driving vigilance estimation is an important task for traffic safety. Nowadays, electroencephalography (EEG) and electrooculography (EOG) have made some achievements in vigilance estimation, but there...
Share article
Ordered micro-nano structured biomaterials for wound healing
December 2024
The complexity of wound healing, influenced by both external factors and internal pathological mechanisms, presents a significant challenge in clinical treatment. However, strategically designed micro-nano...
Share article
Proteomic insights into myopia development: Differential protein expression and the role of calcium signaling in form deprivation myopia in Guinea pigs
September 2024
This study aims to explore the changes in the vitreous proteomics of form deprivation myopia (FDM) in guinea pigs, in order to reveal the molecular mechanisms involved in the onset and development of...
Share article
The therapeutic efficacy of post-symptom 3,4-diaminopyridine treatment in cosmetic injection-induced botulism using a novel animal model
September 2024
In recent years, the incidence of cosmetic injection-induced botulism has remarkably increased due to the frequent usage of botulinum neurotoxin type A (BoNT/A). To mimic and investigate this new clinical...
Share article
Biomaterials for cardiovascular diseases
September 2024
Cardiovascular disease (CVD) remains a leading cause of mortality worldwide, claiming countless lives and posing a formidable health challenge. Extensive efforts have been dedicated to combating this...
Share article
Nano-enhanced nature medicine for ischemic stroke: Opportunities and challenges
September 2024
Ischemic stroke (IS), a major cause of death and disability globally, requires innovative therapeutic approaches due to its complex pathology. Nature medicine (NM) offers promising treatments through...
Share article
Effect of orthotic insole on symptomatic flexible flatfoot in school-age children: Meta-analysis and 1-year follow-up study
September 2024
This study aimed to investigate the efficacy of orthopedic insoles, specifically three-dimensional (3D)-printed orthopedic insoles, for treatment of symptomatic flexible flatfoot in school-age chil...
Share article
Emerging strategies for the treatment of endometriosis
September 2024
Endometriosis is an estrogen-dependent disorder of the reproductive tract, affecting approximately 10 % of women. The symptoms of this condition are vague and not correlated with the disease's stage....
Share article
Bio-inspired hierarchical particles for bioassays
June 2024
Bioassay technology has been proved important in the field of environmental monitoring, disease diagnosis and clinical treatment. At present, diverse bioassay technologies have achieved reliability,...
Share article
Nanomaterials for wound healing: Current status and futuristic frontier
June 2024
Wound healing is a complex process that involves a variety of physical, chemical, and biological processes. Because of their remarkable characteristics and capabilities, nanomaterials have recently...
Share article
A computational model to assess the effectiveness of adhesive materials in restoration of crown-root fractures
June 2024
Fragment reattachment for crown root fractures has become a routinely employed treatment modality with the advancements in adhesive dentistry. Among the majority of documented dental trauma cases, this...
Share article
Application of gas molecules in cancer therapy
June 2024
Gas therapy is currently popular in cancer treatment because of its controllability, effectiveness, and biosafety, as well as the fast development of carriers for gas delivery. Here, we introduce the...
Share article
Polyaryletherketones: Properties and applications in modern medicine
June 2024
Polyaryletherketones (PAEKs) are a family of durable, multifunctional, thermoplastic biopolymers. This article first provides necessary context and thorough information regarding the mechanical, physical,...
Share article
A review on selenium nanoparticles and their biomedical applications
June 2024
Nanotechnology has enormous promise for a wide range of applications in biology. Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing for precision targeting,...
Share article
Pitolisant nanofibers: A promising frontier in drug delivery for narcolepsy - Formulation, optimisation, and characterization insights
June 2024
The study focuses on developing a new way to deliver the narcolepsy medication pitolisant. Electrospinning was used to make polyvinyl alcohol (PVA) and hyperbranched polyglycerol (HPG) polymers into...
Share article
Multiscale polymeric fibers for drug delivery and tissue engineering
March 2024
Owing to their superior capacity for building structures, polymeric fibers with diameters varying from a few nanometers to hundreds of microns have been explored in biomedical applications as drug carriers...
Share article
