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ISSN: 2667-2405

Liquid-liquid phase separation: Fundamental physical principles, biological implications, and applications in supramolecular materials engineering

Liquid-liquid phase separation (LLPS) is a captivating phenomenon in which a uniform mixture spontaneously divides into two liquid phases with differing component concentrations. It is prevalent in...

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Dynamic covalent bond-based materials: From construction to biomedical applications

Dynamic covalent bonds (DCBs) have received significant interest due to their unique reversibility and stimuli-responsiveness. The introduction of DCBs provides materials with self-healing and controllable...

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Hydrogen-bonded supramolecular adhesives: Synthesis, responsiveness, and application

Adhesive bonding to diverse substances is vital to a great number of the established, cutting-edge and emerging applications. We have witnessed, in the last few years, the transformative progress in...

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Self-healing hydrogels based on reversible noncovalent and dynamic covalent interactions: A short review

The self-healing capability of a material refers to its ability to autonomously heal fractures or defects and restore its original structures and functionalities. Self-healing hydrogels, with enhanced...

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Stretchable and self-healable lithium-ion batteries with all-in-one configuration

•The LIB exhibits both stretchability and self-healability.•The electrolyte and electrodes form fused interfaces by the exchange of imine bond.•The LIB can supply power upon stretch or after being cut...

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An injectable macroporous hydrogel templated by gasification reaction for enhanced tissue regeneration

Owing to excellent biocompatibility, tunable modulus to match biological tissues, full of water environment, and wide range of constituents, injectable hydrogels have always been preferred as superior...

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Supramolecular fluorescence biosensing based on macrocycles

Fluorescence sensing converts chemical events into measurable readings by utilizing fluorescence signals for the qualitative or quantitative detection of specific analytes. Supramolecular chemistry,...

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The role of filamentous membraneless organelle in 3UTR-mediated Protein-Protein interfaces and localization: TIGER Domain

Cells contain numerous membrane-less (MLOs) and multiple membrane-bound organelles. Most of the MLOs have a spherical shape except for a few organelles (that have a filamentous appearance, e.g. FXR1...

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Perylene diimide supramolecular aggregates: Constructions and sensing applications

Perylene diimides (PDIs) with high fluorescence quantum yield and well π-conjugated plane have been widely studied to construct supramolecular aggregates via noncovalent interactions and to further...

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Mechanically Interlocked Biomacromolecules

Mechanical interlocking is a prominent phenomenon both in macroscopic objects and in microscopic molecules. Not only is it aesthetically appealing, it also leads to unique properties such as extraordinary...

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Exploring water−macromolecule interactions at the single-molecule level: A comprehensive review

Water is ubiquitous and indispensable on the Earth. Its importance has long been recognized on a macroscopic scale. However, it took a long time to comprehend the impact of water molecules on the microscopic...

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Supramolecular co-assembled hybrid hydrogels for antibacterial therapy

Bacterial infections arising from antibiotic-resistant strains represent a formidable global health threat. In the realm of antibacterial therapies, supramolecular hydrogels stand out with unique advantages...

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Engineering coacervate droplets towards the building of multiplex biomimetic protocells

The origin of life on Earth remains one of the biggest open questions in science. Despite recent advances in molecular mechanism of cell biology, a large blind spot still exists between non-living matter...

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Well-Tunable, 3D-printable, and Fast Autonomous Self-Healing Elastomers

Self-healing elastomers provide extended longevity of functional materials, due to their unique adaptability and durability. However, a major scientific challenge remains in developing materials with...

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Interfacial self-assembly of nanoparticles into macroscopic, monolayered films

This article offers an overview of recent advances in directing self-assembly of nanoparticles (NPs) at the interfaces between two immiscible fluids, which is aimed at emphasizing that the fluidic interfaces...

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Design of a supersoft, ultra-stretchable, and 3D printable hydrogel electrical bioadhesive interface for electromyography monitoring

•PEDOT:PSS-PAA-PAAm hydrogel is designed for electrical bioadhesive interface.•The high sensitivity of EMG monitoring is attributed to the hydrogel's excellent mechanical compatibility.•The tissue-like...

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Fabrication of the polyetherketoneketone-reinforced nano-hydroxyapatite composites as inspired by the cortical bone

•The cortical bone-inspired composites were produced successfully by 20 vol% poly-dopamine (pDA)-nano hydroxyapatite (nHA) and 2 wt% PVA/PEKK.•pDA modified nano hydroxyapatite (nHA) slurries can fabricate...

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Progress for the development of antibacterial surface based on surface modification technology

With the increasing requirement for antibacterial surface especially in biomedical apparatus, constructing the new material surface with bactericidal activity for combating the infection caused by multi-resistant...

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Dynamic covalent epoxy network of hyperbranched-synergistic-supramolecular: Catalyst-free reprocessing, and application in carbon fiber composites recycling

Plastic recycling, especially the recycling of thermosets, is a crucial step towards improving waste management and achieving economic recycling. Here, a method utilizing non-covalent supramolecular...

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Self-powered assemblies for tissue engineering applications

•It systematically summarizes the basic physical rules underlining electric field generations and provide a practical guide for the designing of electrically active supramolecular assemblies.•The general...

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High-sensitivity and damage redundant detection capable gel-state [BMIM][BF4] electronic skin for aerospace applications

Electronic skin (e-skin) holds significant potential for applications in robotics, Internet-of-things, and health monitoring. However, conventional e-skins often exhibit decreased sensitivity and delayed...

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Biodegradable power sources for transient bioelectronics

The development of biodegradable power sources has opened new avenues for transient bioelectronics, offering temporary energy solutions for implantable medical devices. This review presents a systematic...

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Stimuli-responsive hydrogel sponge for ultrafast responsive actuator

lA thermo-responsive PNIPAm hydrogel sponge with locally aggregated PNIPAm polymer network was constructed with the assistance of ice crystals.lThe PNIPAm hydrogel sponge can realize ultrafast de-swelling/swelling...

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Coupling an artificial receptor with macrophage membrane for targeted and synergistic treatment of cholestasis

•Amphiphilic calix[4]arene (AmC4A) is synthesized to bind toxic bile acids (BAs) in a high affinity.•Establishment of a therapeutic platform based upon co-assembly of macrophage membrane and AmC4A.•Ursodeoxycholic...

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A self-cascade terpolymer platform for amplified chemo-chemodynamic therapy with synergistic immunogenic cell death enhancement

Chemodynamic therapy, which relies on the generation of cytotoxic radicals, can be amplified by a nanoplatform that produces hydroxyl radicals while also compromising natural radical scavenging mechanisms....

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