Nanoparticle-based drug delivery systems for cancer therapy
2020
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved efficacy by: 1) increasing half-life...
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Function and treatment strategies of β-hydroxybutyrate in aging
2023
Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy source for life activities, and signals for environmental adaptation. Ketone bodies are important metabolic intermediates...
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Recent progress of 3D printed vascularized tissues and organs
June 2024
Since the need for vascular networks to supply oxygen and nutrients while expelling metabolic waste, most cells can only survive within 200 μm of blood vessels; thus, the construction of well-developed...
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Journey of smart material from composite to shape memory alloy (SMA), characterization and their applications-A review
2023
This review paper deals with the advancements of composites to shape memory alloys. The journey of smart materials from conventional composites to advance shape memory alloys and their application is...
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Stimuli-responsive materials: A smart way to study dynamic cell responses
2022
Cells in the body reside within the extracellular matrix (ECM), a three-dimensional environment that not only provides structural support for the cells, but also influences cellular processes, like...
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Recent advances in hyaluronic acid-based hydrogels for 3D bioprinting in tissue engineering applications
2023
3D bioprinting technology can rapidly process cell-loaded biomaterials to prepare personalized scaffolds for repairing defective tissues, tissue regeneration, and even printing tissues or organs. 3D...
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Inhalable nanomedicine for lung cancer treatment
June 2024
Lung cancer has surpassed other types of cancer to become the primary cause of cancer-related deaths. Surgery stands as the foremost clinical treatment strategy available for tackling this condition,...
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Recent progress in surgical adhesives for biomedical applications
2022
The increasing demands for the management of hemostasis and tissue sealing drive the development of novel bioadhesives, which can overcome the disadvantages of conventional sutures such as additional...
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Bioactive carbon dots for tissue engineering applications
March 2024
Carbon dots (CDs) are carbon-based zero-dimensional nanomaterials with characteristic sizes of less than 10 nm. Recently, bioactive CDs have made remarkable achievements in wound healing, bone and...
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Ultrasound-activated mechanochemical reactions for controllable biomedical applications
December 2024
Intramolecular bonds in small organic molecules, macromolecules, and organic-inorganic hybrids are broken or formed by ultrasound-activated mechanical force that can be applied with spatial and temporal...
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Smart materials for smart healthcare– moving from sensors and actuators to self-sustained nanoenergy nanosystems
2020
Smart materials offer a significant role in on our lives covering various sensing and actuation applications in healthcare due to their responsivity to external stimuli such as stress, light, temperature,...
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Hydrogel wound dressings containing bioactive compounds originated from traditional Chinese herbs: A review
March 2024
Various factors can cause skin defects, resulting in the loss of physiological functions and even death due to severe concurrent infection. Dressings are often clinically used to fully cover the wounds...
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Reactive oxygen species-sensitive materials: A promising strategy for regulating inflammation and favoring tissue regeneration
2023
Reactive oxygen species (ROS), acting as essential mediators in the biological system, highly influence the physiologic and pathologic processes of the human body. The aberrant production of ROS, caused...
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Biosensor-based therapy powered by synthetic biology
2023
The study of synthetic biology focusing on biosensor systems has resulted from a growing interest in developing customized biological devices with desired cellular functions. Recently, biosensors have...
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Current state of art smart coatings for orthopedic implants: A comprehensive review
2023
Biomaterials play a pivotal role in modern orthopedics. There are a plethora of functional issues with orthopedic implants. These issues include things like aseptic loosening, lack of osseointegration,...
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Anti-fouling coatings for blood-contacting devices
March 2024
Blood-contacting medical devices, such as vascular stents, intravascular catheters, and artificial heart valves, frequently encounter complications in clinical practice, including thrombosis, inflammatory...
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Artificial intelligence (AI) meets biomaterials and biomedicine
June 2024
With the rapid progress of information technology and life sciences, artificial intelligence (AI) technology has substantially changed the way in many areas of biomaterials and biomedicine, including...
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A detailed protocol for cell force measurement by traction force microscopy
March 2024
Cellular traction forces (CTFs) are generated by adherent cells and involved in regulating migration, morphology, and homeostasis. Accurate measurement of CTFs is crucial for understanding fundamental...
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Recent advances in three-dimensional printing in cardiovascular devices: Bench and bedside applications
March 2024
Three-dimensional (3D) printing is emerging as an innovative technology, which is widely used in cardiovascular disease at bench and bedside. During the last decade, with the development of 3D printing...
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Design of 3D smart scaffolds using natural, synthetic and hybrid derived polymers for skin regenerative applications
2023
Effective wound care is a major concern as many conventional wound healing methods and materials have failed in facilitating proper healing, instead disrupts the overall healing process, leading to...
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Recent development of implantable and flexible nerve electrodes
2020
Implantable electrical devices offer a variety of potential diagnostic options and treatments in different medical fields. Especially in the absence of specific drugs, the implantable nerve electrodes...
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Tailoring the elasticity of nerve implants for regulating peripheral nerve regeneration
2023
Numerous studies have conducted in-depth research on the biological and chemical properties of tissue-engineered neural graft (TENG) on peripheral nerve regeneration, while the physical properties of...
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Advances of multifunctional hydrogels for periodontal disease
2023
Periodontal disease is a chronic inflammatory disease that develops from dental plaque that affects periodontal supporting tissues. The control of plaque by mechanical therapy has always been the mainstream...
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Emerging polymeric biomaterials and manufacturing-based tissue engineering approaches for neuro regeneration-A critical review on recent effective approaches
2023
The nervous system is a crucial part of the human body that is damaged by traumatic injury, stroke, and neurodegenerative diseases. Recent studies also have shown that neurodegenerative diseases are...
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Externally triggered drug delivery systems
September 2024
Externally triggered drug delivery systems empower patients or healthcare providers to utilize external stimuli to initiate drug release from implanted systems. This approach holds significant potential...
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