The Role of Systemic Inflammatory Response, Hypermetabolism, and Wound Treatment and Repair in Hypernatremia of Severely Burned Patients
Available online 20 February 2025
Hypernatremia represents a critical complication in patients with severe burns. This study aims to further investigate the etiology, clinical features, and therapeutic strategies for hypernatremia in...
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Skin microecology and skin barrier repair, wound healing and appendage regeneration
January 2025
Skin is one of the barriers for organisms to resist the stimulation of the external environment. Hundreds of millions of microorganisms are implanted on the skin surface, and skin microorganisms are...
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Antibiotic-loaded bone cement applied to treatment of refractory hand burn wounds: 7 cases report
January 2025
Our research focuses on the utilization of antibiotic-loaded bone cement in combination with skin graft to effectively treat refractory hand burn wounds, which are often complicated by infection and...
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Low temperatures promote the healing of skin micro-injuries by inhibiting IL1β
January 2025
The human skin holds a remarkable ability to adapt to external temperature changes to maintain thermal regulation and tissue integrity. Current research indicates that exposure to appropriate low temperatures...
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Umbilical cord mesenchymal stem cell exosomes combined with collagen sponges contribute to neovascularization and wound healing in exposed bone wounds
January 2025
Unmanaged bone exposed wounds that don't receive proper treatment can potentially lead to additional complications. Human umbilical cord mesenchymal stem cell (HUC-MSC)-derived exosomes (EXO) have a...
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A feasible clinical pathway of severe pyoderma gangrenosum in burn centers based on three clinical cases
January 2025
To establish a standardized clinical pathway for the management of severe pyoderma gangrenosum (PG) in burn centers by analyzing and integrating insights from three detailed case studies....
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The biology and molecular regulation of MeSCs in hair follicles and their therapeutic potential for hypopigmentation disorders
January 2025
Melanocytes, which produce melanin, a natural pigment, arise from the neural crest during embryonic development. They reside primarily in the epidermis and hair follicles, where they are responsible...
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A case-control study evaluating single and dual layer dermal matrix in treating scar contractures using the Vancouver and POSAS scar scales, and correlations with retraction and function in treating scar contractures
January 2025
The dermal matrix appeared in the late 1990s and became an important tool in burn treatment. Following its success, new matrices soon emerged and were employed to treat burn contracture, but few studies...
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Application of SVF microinjection combined with skin tension in ischemic chronic refractory wounds
January 2025
To compare the healing time of two groups of patients, who were randomly divided into the simple antibiotic ointment dressing change group and the simple antibiotic ointment dressing change with the...
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Role of combined Z-plasty and fractional carbon dioxide laser therapy in improving severe scar contracture of the fingers after burns in children: A retrospective study
January 2025
Repairing severe scarring contractures of the fingers (SSCF) in pediatric patients can be challenging and often yields unsatisfactory outcomes. While either Z-plasty or fractional carbon dioxide laser...
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Investigation of the pain condition in diabetic foot ulcer patients following surgical reconstruction: A cross-sectional observational study
January 2025
Pain is a characteristic manifestation in some patients suffering from diabetic foot ulcers (DFU). However, there have been few studies focusing on the pain experienced by DFU patients and the impact...
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Enhanced healing of burn wounds by dressings with alginate: An updated systematic review and meta-analysis of randomized controlled trials
Available online 27 January 2025
This systematic review and meta-analysis evaluates the effectiveness of alginate dressings for burn treatment....
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Epidemiological features and temporal trends of burns and their subtypes, 1990–2021: findings from the Global Burden of Disease Study 2021
Available online 22 January 2025
Burns present a significant clinical challenge and are a critical global public health concern. Existing studies primarily focus on specific countries or regions, resulting in a lack of comprehensive...
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A free jigsaw puzzle perforator flap for repairing complicated wounds on extremities
Available online 17 January 2025
The single stage reconstruction of complicated wounds on extremities remains difficult due to the extensive skin and soft tissue defects, multiplanar defects requiring three-dimensional repair and functional...
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Cerium-based materials in burn wound healing: development, mechanism and outlook
Available online 16 January 2025
Burn injuries are underestimated trauma that moderate and severe burns are often associated with death. Early excision is the gold standard treatment for burn injuries to reduce the risk of infection,...
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