A retrospective study on the impact of glucocorticoids on the efficacy of posaconazole in the prevention/treatment of invasive fungal infections in patients with hematological malignancies
Available online 17 March 2025
Posaconazole (PCZ) has been used to prevent and treat invasive fungal infections in immunocompromised patients with hematological malignancies. There is a significant correlation between plasma drug...
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Mechanistic investigation of Kuntai capsule in endometriosis treatment: A network pharmacology, molecular docking, and molecular dynamics simulation approach
Available online 13 March 2025
To explore the mechanism of action of Kuntai capsule in the treatment of endometriosis (EMT)....
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Simultaneous determination of concentration of sulfamethoxazole and trimethoprim in human plasma by dual-quaternary HPLC and its clinical application
Available online 13 March 2025
Sulfamethoxazole compound, a combination of sulfamethoxazole and trimethoprim, is commonly prescribed to organ transplant recipients for infections caused by Nocardia, Burkholderia cepacia, and Pneumocystis...
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Effects of lianggu decoction combined with Gonal-F on IVF outcomes, embryo quality, and pregnancy in infertility patients undergoing IVF-ET
Available online 12 March 2025
To investigate the effects of Lianggu decoction combined with Gonal-F on the outcomes of in vitro fertilization and embryo transfer (IVF-ET) outcomes in infertility patients, including embryo quality...
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Effects of donepezil on emotion, cognitive function, and inflammatory factors in patients with Hashimoto's thyroiditis
Available online 12 March 2025
To investigate the impact of donepezil on emotional responses, cognitive function, and inflammatory factors in patients with Hashimoto's thyroiditis (HT)....
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Application status of traditional computational methods and machine learning in cancer drug repositioning
Available online 3 March 2025
The escalating global burden of cancer has spurred extensive research and development efforts aimed at discovering effective anti-cancer agents. However, the prohibitively high costs associated with...
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Therapeutic drug monitoring for promotion of rational medication in the elderly: Overview, challenges and opportunities
November 2024
In the context of rapid development of clinical pharmacy in China, therapeutic drug monitoring (TDM) has become a vital tool for rational medication and is widely concerned. TDM combines the knowledge...
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Precision individualized medication strategies and challenges for cardiovascular diseases
November 2024
With the ongoing societal development and changes in lifestyle, the incidence of cardiovascular diseases continues to rise. Although the most effective means of preventing atherosclerotic cardiovascular...
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Unlocking precision medicine: Innovative strategies for druggable target identification and therapeutic enhancement
November 2024
Precision medication emphasizes tailored treatment approaches based on individual patient characteristics, yet the limitations in current drug target identification hinder therapeutic advancements....
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Surgical pharmacy for catalyzing pharmacy service throughout surgical continuum
November 2024
The greater the complementarity between pharmacists’ knowledge and doctors’ knowledge, the more significant the role pharmacists can play in clinical practice. Physicians extensively use drugs for disease...
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Current status and prospects of nucleic acid mass spectrometry in clinical pharmacogenomics
November 2024
Pharmacogenomics is an essential means to achieve personalized medicine. Multi-gene and multi-loci panel testing is an inevitable trend in its development, comprehensively analyzing the impact of genes...
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Integrating pharmacy practice into precision emergency medicine: A pathway to enhanced patient care
November 2024
Precision emergency medicine (EM) represents a transformative approach to healthcare, integrating advanced technologies and human-centric data to tailor treatments to individual patient needs. This...
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Towards precision medicine: Leading with big data and multidisciplinary collaboration
November 2024
Precision medicine relies on individuals’ genetic information, omics characteristics, and environmental factors to achieve personalized disease prevention, diagnosis, and treatment. With the successful...
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Research progress on regulation of mitochondrial function by traditional Chinese medicine in alleviating acetaminophen-induced liver injury
November 2024
Drug-induced liver injury is a significant contributor to cases of acute liver failure and the primary reason for drug withdrawal due to safety concerns. Acetaminophen (N-acetyl-para-aminophenol, APAP)...
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