Exosomes for skin treatment: Therapeutic and cosmetic applications
December 2024
The therapeutic potential of exosomes, which are nano-sized extracellular vesicles derived from various cell types, have drawn substantial interest in the field of dermatology. Exosomes have distinctive...
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Two heads are better than one: Unravelling the potential Impact of Artificial Intelligence in nanotechnology
December 2024
Artificial Intelligence (AI) and Nanotechnology are two cutting-edge fields that hold immense promise for revolutionizing various aspects of science, technology, and everyday life. This review delves...
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Lipoic acid-based poly(disulfide)s: Synthesis and biomedical applications
September 2023
Biodegradable and adaptable polymeric materials are currently being studied due to their wide scope of potential applications, from nanomedicine to novel multifunctional materials. One such class of...
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Chitosan nanoparticle delivery systems: An effective approach to enhancing efficacy and safety of anticancer drugs
December 2024
Currently, cancer is the leading cause of death globally. In the absence of specific treatment and early diagnosis, procedures like surgery, chemotherapy, and radiation therapy are often used to manage...
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Quercetin-encapsulated GelMa hydrogel microneedle reduces oxidative stress and facilitates wound healing
December 2024
Delayed wound healing brings additional physical, mental, and financial burdens. Microneedles (MNs) are a novel dressing form and can incorporate drug delivery systems. Quercetin is known for its remarkable...
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Edible plant-derived extracellular vesicles serve as promising therapeutic systems
September 2023
Extracellular vesicles (EVs), which are natural nanocarriers characterized by a phospholipid bilayer structure, are released by living cells. They play a crucial role in the intercellular transport...
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Novel drug delivery systems: Insight into self-powered and nano-enabled drug delivery systems
December 2024
Novel drug delivery systems comprise sophisticated technology merged into drug delivery systems. These systems are created with the aim of addressing the limitations of conventional drug delivery systems....
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Profilometry and atomic force microscopy for surface characterization
March 2023
Aim: This study aims to evaluate and compare the profilometry and atomic force microscopy (AFM) for characterization of biomaterial surfaces. Method: The clinically commonly used titanium (Ti) was used...
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Phytomedicine meets nanotechnology: A cellular approach to rheumatoid arthritis treatment
December 2024
Rheumatoid arthritis (RA) is an autoimmune condition causing synovitis, joint dysfunction, and tissue deterioration. This review highlights the pathophysiology of RA, including the involvement of cellular...
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Comparative efficacy and safety of bisphosphonate therapy for bone loss in individuals after middle age: A systematic review and network meta-analysis
March 2022
PURPOSE: The purpose of this study was to estimate the benefits and drawbacks of bisphosphonates in the treatment of osteoporosis and osteopenia in middle-aged and elderly individuals....
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Biogenic silver nanoparticles from Simarouba glauca DC leaf extract: Synthesis, characterization, and anticancer efficacy in lung cancer cells with protective effects in Caenorhabditis elegans
December 2024
This study explores the synthesis, characterization, and biomedical applications of silver nanoparticles (AgNPs) synthesized using Simarouba glauca leaf extract. The biogenic AgNPs were characterized...
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Advances in clinical application of nanoparticle-based therapy for cancer treatment: A systematic review
December 2024
Due to the rapid development of nanotechnology and nanocomplex synthetic techniques, a large number of nanoparticle-based cancer medicines have been evaluated or applied in clinical trials for utility....
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Two-dimensional nano-biomaterials in regulating the tumor microenvironment for immunotherapy
December 2024
Two-dimensional (2D) nanomaterials, characterized by their ultrathin profile and constructed from single or a few atomic layers, exhibit unique physical and chemical properties. These materials have...
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Recent advances in macrophage-derived exosomes as delivery vehicles
December 2022
Macrophages are important members of the innate immune system that can be reversibly polarized by different microenvironment signals. Exosomes secreted from cells are lipid bilayer membrane vesicles...
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Green synthesis of palladium nanoparticles using Asterarcys sp. and their applications
December 2024
Asterarcys-mediated algal extract, which is non-toxic and renewable, was used to synthesize palladium nanoparticles (PdNPs) efficiently and ecologically friendly. The palladium nanoparticle's fabrication...
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Photothermal/photodynamic antibacterial hydrogel embedded with copper carbon dots and Au nanoparticles
December 2024
In this paper, we created a hydrogel (named AuNPs-CuCCDs@Gel) with photothermal and photodynamic performance through incorporating copper carbon dots (CuCCDs) and Au nanoparticles (AuNPs) into gelatin...
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Recent plant-synthesized gold nanoparticle advancements for gastric cancer therapy
December 2024
Gastric cancer is the fifth most common form of cancer across the globe, according to the latest WHO GLOBO-CAN 2022 report. Metal nanoparticles (MNPs) have been attracting attention for cancer therapy...
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Advances of calcium phosphate nanoceramics for the osteoinductive potential and mechanistic pathways in maxillofacial bone defect repair
December 2024
Maxillofacial bone defects, arising from congenital malformations, tumors, infections, and traumas, represent a common clinical condition that impairs patients' appearance, speech, and motor functions....
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The challenges to develop antibody-conjugated nanomedicine products
December 2023
Nanomedicine becomes a key player especially as next generation medicine. Antibody-conjugated nanomedicine could significantly upgrade the treatment and expand application areas. However, there are...
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Biomimetic nanocarriers harnessing microbial metabolites usher the path for brain disease therapy
December 2023
The gastrointestinal system, often regarded as the 'second brain of humanity,' maintains a profound connection with the cerebral realm. Unlocking the intricate metabolic pathways of gut microorganisms...
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Application of telomere biology and telomerase in mesenchymal stem cells
December 2022
With the increasing understanding of mesenchymal stem cells (MSCs), their potential in tissue engineering and regenerative medicine has attracted more attention. However, some important problems need...
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Ultrasound-triggerennd piezocatalytic conductive Guar gum/PEDOT: PSS/BTO composite hydrogels for bacterial-infected skin wound healing
December 2024
Open skin wounds are susceptible to infections by multidrug-resistant bacteria, which can lead to delayed wound healing or worsening of symptoms. Therefore, there is an urgent need to develop a comprehensive...
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Skin biomechanics: Breaking the dermal barriers with microneedles
March 2022
Microneedles (μND) are promising devices that can be used to transport a wide variety of active compounds into the skin. To serve as an effective delivery system, μND must pierce the human stratum corneum...
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Anticancer lipid-based drug delivery systems: Basic knowledge and recent applications
Available online 17 October 2024
Cancer is a complicated disease that thrives on certain features collectively known as cancer hallmarks (e.g. growth signals autonomy, evading apoptosis, evading immune system, ability of metastasis,...
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Tumor microenvironment responsive nanozymes for multimodal imaging of tumors
December 2024
Nanozymes exhibit immense potential and promising prospects in the realm of diagnostic imaging and tumor therapy, owing to their inherent physicochemical properties and enzymatic activities. With the...
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