Revolutionizing Cancer Treatment: Impact of Nanotechnology on Drug Delivery and Targeted Therapies

Cancer continues to claim countless lives and compromise the well-being of individuals worldwide. Despite ongoing efforts to improve therapies and enhance patient experience, there are limitations in the effectiveness of existing cancer treatments.

Key to optimizing cancer treatment is the early detection of malignant cells and the precise delivery of highly specific drugs to minimize toxicity. Traditional diagnostic and therapeutic methods often come with systemic toxicity and limited efficacy, prompting the exploration of nanotechnology as a potential solution to improve diagnosis and mitigate disease severity.

In recent years, the rapid evolution and widespread application of nanotechnology across diverse fields have presented a novel opportunity to advance cancer diagnosis and treatment. Nanotechnology's entry into cancer therapeutics has sparked substantial interest, particularly in the development of nano-drug delivery systems and nanomedicine. Their inherent biocompatibility, potential for selectivity, and efficient drug delivery mechanisms have positioned them as promising tools in the fight against cancer. Moreover, these systems have expanded their payload capabilities beyond organic drug molecules to encompass proteins, RNA, vaccines, and supplements. Addressing critical issues such as poor solubility, low bioavailability, and stability, nano-drug delivery systems would not only induce targeting and selectivity, but also circumvent challenges in drug formulation, particularly in drug delivery and targeting which is a key issue and challenge for effective treatment on cancer.

Topics covered:

This special issue aims to spotlight recent breakthroughs, ongoing developments and future prospects in:

1) the design, characterization, and biological assessment of nanomedicine-based drug delivery systems;

2) Nano delivery systems;

3) Nanomaterials in cancer management from their physicochemical to biological properties;

4) the hurdles impeding the translational success of various nanomaterials within specific cancer contexts;

5) a comprehensive understanding of their limitations in clinical settings; and

6) Cancer Targeting methods.

Important Deadlines:

Submission deadline:  December 31, 2024

Submission Instructions:

Please read the Guide for Authors before submitting. All articles should be submitted online, please select [VSI:Revolutionizing Cancer Treatment] on submission.

Guest Editors:

Dr. Mohammad Najlah

Faculty of Health, Education, Medicine and Social Care, United Kingdom

Email: mohammad.najlah@aru.ac.uk

Dr. Wei Chen

Xi’an Jiaotong-Liverpool University, Suzhou, China

Email: Wei.Chen03@xjtlu.edu.cn