Truncated enhanced constraint for low-rank plus sparse in cardiac dynamic MRI reconstruction
May 2026
Cardiac dynamic MRI has been widely used in cine and perfusion imaging, in which low-rank and sparse priors play an important role in reconstructing dynamic images with high temporal and spatial resolution...
Single-scan ultra-selective probing on targeted components from overlapped NMR spectra
May 2026
Benefitting from the non-invasive and quantitative detection property, liquid NMR spectroscopy shows broad applications in the identification, separation, and structural determination of chemical substances...
Structural anisotropy in celery stalks by microscopic MRI and polarized light microscopy
May 2026
Structural anisotropy of celery stalks was studied using T2 anisotropy in microscopic MRI (μMRI) and supplemented by quantitative polarized light microscopy (PLM) at optical resolutions. Parenchyma,...
Fragment-based discovery of TopBP1 inhibitors integrated with AI-driven molecular docking
May 2026
DNA topoisomerase IIβ-binding protein 1 (TopBP1) converges on multiple oncogenic pathways, e.g., Rb, p53, and PI3K/Akt, which are hallmarks of most cancer progression. However, the lack of structural...
A random fractional 13C labeling strategy for P. pastoris expressed eukaryotic membrane proteins for solid-state NMR studies
May 2026
Solid-state NMR (SSNMR) has emerged as an important technique for characterizing membrane protein structures. Using sparse 13C labeling of membrane proteins can significantly enhance spectral resolution....
OFC: Outside Front Cover
May 2026
Spin-echo measurements for capillary rheometry at low field
May 2026
A single spin-echo, acquired in the presence of a constant magnetic field gradient, has a phase proportional to the average velocity of the sample and an amplitude determined by the distribution of...
Passive water exchange between multiple sites can explain why apparent exchange rate constants depend on ionic and osmotic conditions in gray matter
May 2026
Porous materials, such as biological tissue, often have heterogeneous microstructures where imbibed fluid experiences distinct environments on short timescales, but can exchange among different environments...
Mean pore diameters of 3D printed micro-capillaries using the matrix pencil method
May 2026
The matrix pencil method (MPM) is an approach for quantitative analysis of the multi-exponential time-domain signals from relaxation and diffusion NMR experiments. In contrast to other signal processing...
FlexCENT: A frequency-flexible CEST imaging network combining frequency offset encoding and three-dimensional U-Net
May 2026
This study proposes a deep learning-based method termed frequency-flexible chemical exchange saturation transfer (CEST) imaging network (FlexCENT), which enables robust CEST quantification across variable...
The perspective of artificial intelligence for NMR
Available online 28 May 2026
Nuclear magnetic resonance (NMR) spectroscopy is an indispensable analytical technique in chemistry, biology, and medicine, offering molecular-level structural and dynamic insights for metabolite identification...
Local structure investigations on the defects in metal-organic frameworks
Available online 25 May 2026
Solvent-dependent of Pt/MoS2 electrocatalytic activity toward ethanol oxidation reaction studied by in situ electrochemical NMR spectroscopy
Available online 20 May 2026
In this work, MoS2 was prepared as a supporting matrix for Pt via a hydrothermal method using different solvents, and the electrocatalytic activity of Pt/MoS2 for the ethanol oxidation reaction was...
A designed fusion tag improves soluble expression of nanobody in E. coli
Available online 15 May 2026
Nanobodies are small, single-domain antibody fragments derived from camelid heavy-chain antibodies that offer high stability, strong binding affinity, and excellent potential for therapeutic and diagnostic...
A low-frequency pulsed EPR spectrometer for hyperfine clock transition measurement
Available online 14 May 2026
Low-frequency electron paramagnetic resonance (EPR) spectroscopy proves large sample space and special selectivity to hyperfine spin related transitions in molecules. For instance, the hyperfine clock...
Solid-state NMR spectroscopy study of niobium-doped optical glass
Available online 29 April 2026
In vivo targeted MRS detection of 2-hydroxyglutarate molecules in IDH-mutant gliomas via spin regulation
Available online 13 April 2026
2-hydroxyglutarate (2-HG) is a key metabolic biomarker for identifying IDH-mutant gliomas. Non-invasive and accurate detection of 2-HG is of great significance for the early diagnosis of diseases and...
A hybrid deep learning framework based on VGG19 and U-Net for accurate brain tumor segmentation in MRI images
Available online 11 April 2026
Accurate segmentation of brain tumors from magnetic resonance imaging (MRI) is a critical task in neuro-oncology, directly impacting diagnosis, treatment planning, and patient outcomes. This study presents...
Effect of basis choice on quantitative parameter estimation in accelerated subspace reconstructions
Available online 10 April 2026
This work assesses the effects of different simulated and data-driven subspaces on quantitative parameter estimation in highly accelerated subspace reconstructions. Three different methods for generating...
Physics-embedded CycleGAN for robust metabolite mapping in short-readout deuterium metabolic imaging
Available online 6 April 2026
Deuterium metabolic imaging (DMI) enables noninvasive, spatially resolved mapping of in vivo metabolism by tracking deuterium-labeled substrates and downstream products, yet it is frequently signal-to-noise-ratio...
Design of a fast broadband RF switch for multi-nuclear NMR in lithium-ion batteries
Available online 31 March 2026
To address the need for observing the electrolyte influenced by dissolved metal ions during the charge and discharge process of lithium-ion battery, a fast-switching broadband radio frequency (RF) switch...
Elucidating chain conformation in interfacial and crystalline domains of polyethylene-like polyesters by solid-state NMR
Available online 25 March 2026
NMR insights into the role of urea in cellulose dissolution: a stoichiometric study of cellobiose in NaOH/urea aqueous solution
Available online 25 March 2026
The mechanism underlying the enhanced dissolution of cellulose in NaOH/urea aqueous solutions has long been a subject of debate. In this study, high-resolution solution-state 1H and 13C DEPTq NMR spectroscopy...
Dimerization-induced conformational transitions of yeast iso-1 cytochrome c
Available online 23 March 2026
Cytochrome c is a multifunctional protein involved in electron transport and apoptosis. However, its conformational landscape is complex and heterogeneous, which has obscured the functional understanding—particularly...
Temperature dependence of two or more water species in delignified wood and lignocellulosic, tracked by LFNMR relaxometry
February 2026
Distributions of nuclear magnetic resonance (NMR) relaxation times provide detailed information about the water in wood. This study documents the water dynamics analysis of T2 and T1 distributions for...
