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ISSN: 2957-3912

Ketamine and its two enantiomers in anesthesiology and psychiatry: A historical review and future directions

Ketamine, a dissociative anesthetic, is widely utilized in both human and veterinary anesthesia. Its (S)-enantiomer, esketamine, is similarly employed for anesthesia and analgesia. The anesthetic effects...

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Nomogram-based prediction of emergence delirium in elderly patients undergoing laparoscopic surgery

A nomogram model has been developed to forecast the incidence of emergence delirium (ED) in elderly patients undergoing laparoscopic surgery....

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Case report: Successful reversal of chronic kidney disease by epidural block with lidocaine

IgA nephropathy (IgA N) is a leading cause of chronic kidney disease (CKD) and renal failure. However, none of the information regarding the pathogenesis of this disease suggests a curable time-limited...

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Activation of ACE2/Ang-(1–7)/Mas axis improves cognitive dysfunction induced by isoflurane in mice via inhibiting oxidative stress

Long-term inhalation anesthesia is known to be associated with postoperative cognitive dysfunction. Our previous studies have confirmed that oxidative stress damage contributes to its mechanistic connection....

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The effect of perioperative intravenous lidocaine infusion on postoperative sleep of elderly patients with colorectal cancer: A randomized controlled study

Postoperative sleep disturbance (POSD) caused by postoperative pain can impede the enhanced rapid recovery of elderly patients with colorectal cancer. We propose that perioperative intravenous lidocaine...

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Directions for analgesic development

Physiological pain represents a protective response to avoid further injury and is helpful for survival. However, pathological pain is a common disease/symptom significantly affecting the quality of...

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Publication trends and research hotspots of IL-1: A bibliometric analysis of IL-1 with relevance to anesthesia in highly cited papers from WoSCC

The IL-1 family has been discovered for more than 40 years, and its roles have been extensively explored in numerous studies, involving innate immunity, acquired immunity, and many inflammatory-associated...

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Substantial challenge for a patient with severe mitral regurgitation and pulmonary hypertension undergoing transcatheter mitral valve edge-to-edge repair procedure

The transcatheter mitral valve edge-to-edge repair (TEER) procedure is a percutaneous transcatheter intervention for severe mitral regurgitation in patients deemed to have significant comorbidities....

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Acquisition and validation of four pain subtypes of colon adenocarcinoma and prognostic analysis

Colon adenocarcinoma (COAD) is the most common type of colorectal cancer. Pain is a multidimensional unpleasant experience involving various molecular and cellular pathways. Nevertheless, the exploration...

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Neuroprotective effects of dantrolene in neurodegenerative disease: Role of inhibition of pathological inflammation

Neurodegenerative diseases (NDs) refer to a group of diseases in which slow, continuous cell death is the main pathogenic event in the nervous system. Most NDs are characterized by cognitive dysfunction...

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Association between echocardiographic features, troponin levels, and survival time in hospitalized COVID-19 patients with cardiovascular events

This study aims to explore the predictive roles of echocardiographic parameters and biomarkers in determining outcomes among hospitalized COVID-19 patients experiencing cardiovascular events....

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Hoarseness after general endotracheal anesthesia: A single-center retrospective analysis

After the extubation of endotracheal tubes or removal of laryngeal masks in patients who underwent general anesthesia, complications such as hoarseness often occur, potentially leading to serious adverse...

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The impact of novel coronavirus infection on blood pressure variability in patients undergoing painless gastrointestinal endoscopy

This study aims to examine the impact of COVID-19 infection on blood pressure variability among patients undergoing painless gastrointestinal endoscopy....

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Effect of remimazolam on postoperative sleep quality in patients undergoing laparoscopic hysterectomy: A randomized controlled trial

Remimazolam is a new sedative-hypnotic drug, which has been demonstrated to be safe and effective for the induction and maintenance of anesthesia, but its effects on the postoperative sleep quality...

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Perfluorocarbon-based oxygen carriers: What is new in 2024?

Perflurocarbon-based oxygen carriers (PBOC) represent a major category of artificial oxygen therapeutics. Since their initial report of potential oxygen-carrying capability half a century ago, some...

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Association between opioids use and risk of multiple cancers: A two-sample Mendelian randomization study

Previous observational studies have investigated the possible link between opiate use and the risk of cancer. Nevertheless, there is still no solid evidence linking opioids to any particular type of...

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Long-Term Outcomes Following Implementation of an Enhanced Recovery after Cardiac Surgery (ERACS) Program

Background: Enhanced recovery after surgery (ERAS) protocol strategies can shorten the hospital stays and ICU stays of patients undergoing cardiac valve surgery. The aim of this study was to explore...

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Single-unit vs Multiple-unit Transfusion During Curative Cancer Surgery: A Prospective Observational Study

Introduction: Blood transfusions can be lifesaving interventions but have also been linked with increased rates of postoperative complications. It has been shown that even one unit of blood transfused...

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Remimazolam as a Potential Alternative to Propofol for General Anesthesia: A Meta-Analysis of Randomized Controlled Trials

Objective: This meta-analysis aimed to systematically review randomized controlled trials (RCTs) to evaluate whether remimazolam can be an alternative to propofol for general anesthesia....

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A Case Report: Application of NMBAs Significantly Improve Oxygenation of the COVID-19 Patient

The Coronavirus disease 2019 (COVID-19) pandemic is caused by the novel human coronavirus SARS-CoV-2. Major complications include pneumonia and acute respiratory distress syndrome. The development of...

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Investigation and Analysis of Post-traumatic Stress Disorder and Coping Style of Health-care Workers after Fighting COVID-19 in Wuhan, China

Introduction: The global spread of COVID-19 is occurring at an alarming rate. Nevertheless, there appears to be insufficient attention directed towards the mental state of frontline health-care workers...

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Recommendations on Perioperative Management and Emergency Intubation for Patients with Omicron

The Chinese National Health Commission adopted the strategy of "Category B and Category B Management" for Omicron infection on January 8, 2023, which might have triggered the recent Omicron epidemic...

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Dexmedetomidine for the Management of Postoperative Catheter-Related Bladder Discomfort: A Systematic Review and Meta-Analysis

Postoperative catheter-related bladder discomfort (CRBD) is a common clinical syndrome that occurs after urinary catheterization. The aim of this systematic review and meta-analysis was to evaluate...

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