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ISSN: 2957-3912

Postoperative Sore Throat After General Anesthesia: A Narrative Review

Endotracheal intubation is a common operation that provides effective mechanical ventilation under general anesthesia. Additionally, it may limit aspiration of upper airway content to the lower airways....

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Perfluorocarbon-based oxygen carriers: What is new in 2024?

Perflurocarbon-based oxygen carriers (PBOC) represent a major category of artificial oxygen therapeutics. Since their initial report of potential oxygen-carrying capability half a century ago, some...

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Trends in Perioperative Cardiac Output Monitoring Techniques

This article briefly reviewed the currently available techniques and commercially available monitors for the measurement of cardiac output in the management of critically ill patients and perioperative...

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Ketamine and its two enantiomers in anesthesiology and psychiatry: A historical review and future directions

Ketamine, a dissociative anesthetic, is widely utilized in both human and veterinary anesthesia. Its (S)-enantiomer, esketamine, is similarly employed for anesthesia and analgesia. The anesthetic effects...

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Lung Protection of Mechanical Ventilation during Laparoscopic Surgery: A Systematic Review

Mechanical ventilation is a means of life support for patients with acute respiratory failure, and it is also an indispensable technical method for ensuring the safety of patients during general anesthesia....

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Hoarseness after general endotracheal anesthesia: A single-center retrospective analysis

After the extubation of endotracheal tubes or removal of laryngeal masks in patients who underwent general anesthesia, complications such as hoarseness often occur, potentially leading to serious adverse...

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Neuroprotective effects of dantrolene in neurodegenerative disease: Role of inhibition of pathological inflammation

Neurodegenerative diseases (NDs) refer to a group of diseases in which slow, continuous cell death is the main pathogenic event in the nervous system. Most NDs are characterized by cognitive dysfunction...

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Directions for analgesic development

Physiological pain represents a protective response to avoid further injury and is helpful for survival. However, pathological pain is a common disease/symptom significantly affecting the quality of...

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Case report: Successful reversal of chronic kidney disease by epidural block with lidocaine

IgA nephropathy (IgA N) is a leading cause of chronic kidney disease (CKD) and renal failure. However, none of the information regarding the pathogenesis of this disease suggests a curable time-limited...

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Homemade Portable High-flow Nebulized Oxygen Therapy Device Used During the COVID-19 Pandemic to Improve Blood Oxygen Saturation in Critically Ill Patients: A Two-Case Report

Background: We designed a portable high-flow nebulized oxygen therapy device to temporarily provide respiratory support and maintain blood oxygen saturation for 2 elderly patients with respiratory failure...

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Remimazolam as a Potential Alternative to Propofol for General Anesthesia: A Meta-Analysis of Randomized Controlled Trials

Objective: This meta-analysis aimed to systematically review randomized controlled trials (RCTs) to evaluate whether remimazolam can be an alternative to propofol for general anesthesia....

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Association between opioids use and risk of multiple cancers: A two-sample Mendelian randomization study

Previous observational studies have investigated the possible link between opiate use and the risk of cancer. Nevertheless, there is still no solid evidence linking opioids to any particular type of...

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Nomogram-based prediction of emergence delirium in elderly patients undergoing laparoscopic surgery

A nomogram model has been developed to forecast the incidence of emergence delirium (ED) in elderly patients undergoing laparoscopic surgery....

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Association between echocardiographic features, troponin levels, and survival time in hospitalized COVID-19 patients with cardiovascular events

This study aims to explore the predictive roles of echocardiographic parameters and biomarkers in determining outcomes among hospitalized COVID-19 patients experiencing cardiovascular events....

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Publication trends and research hotspots of IL-1: A bibliometric analysis of IL-1 with relevance to anesthesia in highly cited papers from WoSCC

The IL-1 family has been discovered for more than 40 years, and its roles have been extensively explored in numerous studies, involving innate immunity, acquired immunity, and many inflammatory-associated...

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Acquisition and validation of four pain subtypes of colon adenocarcinoma and prognostic analysis

Colon adenocarcinoma (COAD) is the most common type of colorectal cancer. Pain is a multidimensional unpleasant experience involving various molecular and cellular pathways. Nevertheless, the exploration...

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The effect of perioperative intravenous lidocaine infusion on postoperative sleep of elderly patients with colorectal cancer: A randomized controlled study

Postoperative sleep disturbance (POSD) caused by postoperative pain can impede the enhanced rapid recovery of elderly patients with colorectal cancer. We propose that perioperative intravenous lidocaine...

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The Effectiveness of Implementation of Surgical Safety Checklist in Different Countries: A Systematic Review

Background: The Surgical Safety Checklist (SSC) was created by the World Health Organization to improve patient safety and studies have shown that this checklist can significantly improve perioperative...

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Effect of remimazolam on postoperative sleep quality in patients undergoing laparoscopic hysterectomy: A randomized controlled trial

Remimazolam is a new sedative-hypnotic drug, which has been demonstrated to be safe and effective for the induction and maintenance of anesthesia, but its effects on the postoperative sleep quality...

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The Effects of Dexmedetomidine on Postoperative Sleep in Elderly Patients: A Systematic Review and Meta-Analysis

Background: Postoperative sleep disorders in elderly patients may increase the risk of postoperative delirium or cognitive dysfunction and delay recovery. Therefore, it is imperative to develop innovative...

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Effects of Dexmedetomidine on Perioperative Brain Protection in Elderly Frail Patients

With the rapid growth of the elderly population and advancements in surgical and anesthesia techniques, an increasing number of elderly patients are opting for surgery. Among them, the number of frail...

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Activation of ACE2/Ang-(1–7)/Mas axis improves cognitive dysfunction induced by isoflurane in mice via inhibiting oxidative stress

Long-term inhalation anesthesia is known to be associated with postoperative cognitive dysfunction. Our previous studies have confirmed that oxidative stress damage contributes to its mechanistic connection....

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Dexmedetomidine for the Management of Postoperative Catheter-Related Bladder Discomfort: A Systematic Review and Meta-Analysis

Postoperative catheter-related bladder discomfort (CRBD) is a common clinical syndrome that occurs after urinary catheterization. The aim of this systematic review and meta-analysis was to evaluate...

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Perspectives on Propofol Anesthesia Research

Propofol is a commonly used intravenous anesthetic with a complex mechanism of action that has been extensively studied in recent years. The study of propofol has provided valuable insights into the...

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Substantial challenge for a patient with severe mitral regurgitation and pulmonary hypertension undergoing transcatheter mitral valve edge-to-edge repair procedure

The transcatheter mitral valve edge-to-edge repair (TEER) procedure is a percutaneous transcatheter intervention for severe mitral regurgitation in patients deemed to have significant comorbidities....

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