The Role of CRISPR/Cas9 in Revolutionizing Duchenne Muscular Dystrophy Treatment: Opportunities and Obstacles
Available online 13 October 2024
Duchenne Muscular Dystrophy (DMD) is a severe X-linked disorder characterized by progressive muscle degeneration, leading to loss of ambulation, respiratory failure, and premature death. It affects...
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The pathogenesis of B-cell non-hodgkin lymphoma associated with HBV (hepatitis B virus) infection is regulated by c-Myc/PD-L1 signaling pathway
Available online 24 August 2024
HBV is closely associated with the incidence of B-NHL (B-cell non-hodgkin lymphoma). This project intends to establish HBV infection-induced B-NHL cells and animal models to clarify the mutual mechanism...
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A scarce case: co-occurrence of Neurofibromatosis Type 1 and Klinefelter Syndrome
Available online 30 September 2024
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with a heterogeneous group of symptoms, including characteristic cafe-au-lait macules, axillary or inguinal freckling, Lisch nodules,...
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Research progress of circular RNA FOXO3 in diseases(Review)
Available online 5 October 2024
Circular RNAs (circRNAs) are a newly discovered class of endogenous non-coding RNAs with a closed-loop structures, and they exert crucial regulatory functions in diverse biological processes and disease...
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Case Report: Alpha6 integrin disorder presenting in childhood with nail dysplasia and onycholysis but no history of fragile or bullous skin changes
Available online 30 September 2024
We report a 7-year-old girl born with pyloric atresia but without congenital epidermolysis bullosa or skin fragility. Nail dysplasia developed at age 8 months and throughout childhood she suffered from...
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