Nanoscale synthetic biology with innovative medicinal applications
Available online 16 November 2024
The rapid advancement of synthetic biology and nanoscience has given rise to a new research field, known as nanoscale synthetic biology (NSB). This field emphasizes the interactions and coordination...
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Nucleon charge and magnetisation distributions: flavour separation and zeroes
Available online 15 November 2024
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Investigating the drivers of negative diversity-invasibility relationship: The role of nutrient availability, allelopathy, soil biota, and soil legacy effects
Available online 15 November 2024
•Nutrient addition, allelopathy, soil biota, and legacy effects impacted plants.•Allelopathy and soil microbes were key factors in invasion resistance.•Diverse native communities suppressed invasives,...
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Engineered Bacteria: Strategies and Applications in Cancer Immunotherapy
Available online 13 November 2024
Cancer therapy remains a critical medical challenge. Immunotherapy is an emerging approach to regulating the immune system to fight cancer and has shown therapeutic potential. Due to their immunogenicity,...
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Towards the generation of polycarpic perennial rapeseeds
Available online 13 November 2024
Perennial crops are increasingly recognized as a sustainable agricultural solution that provides significant advantages over annual crops, including reduced seed input and management cost, improved...
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Recent advances in ultrasound-targeted nanobubbles combined with cancer immunotherapy: Mechanisms, applications, and challenges
Available online 13 November 2024
Immunotherapy has revolutionized cancer treatment by leveraging the immune system to target tumors. However, its efficacy is often limited by the immunosuppressive tumor microenvironment and the development...
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Cannabichromene from full-spectrum hemp extract exerts acute anti-seizure effects through allosteric activation of GABAA receptors
Available online 13 November 2024
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PIAS4 regulates pluripotency exit and cell fate commitment in porcine embryonic stem cells
Available online 12 November 2024
Post-translational modifications (PTMs) are dynamic processes that regulate cell states by enhancing proteome diversity. However, the overall impact of PTMs on pluripotency exit in porcine embryonic...
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Enabling Beam-Scanning Antenna Technologies for Terahertz Wireless Systems: A Review
Available online 12 November 2024
Due to the exponentially growing global mobile data of wireless communications evolving from 5G to 6G in recent years, research activities of leveraging terahertz (THz) waves to obtain larger channel...
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Toward in situ characterization for advancing membrane performance in water treatment processes
Available online 9 November 2024
•Membrane technology greatly improved water treatment efficiency was illustrated.•Ex situ characterization techniques enhanced membrane behaviors was reviewed.•In situ characterization techniques for...
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Application of artificial intelligence in life science: Historical review and future perspectives
Available online 8 November 2024
The fast advancement of artificial intelligence (AI) technologies in recent years, especially the deep learning algorithm and transformer neural network, has brought great impacts on scientific researches....
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Organophosphate esters in Tianshan glacier runoff: Occurrence, degradation, risk, and flux
Available online 8 November 2024
Organophosphate esters (OPEs) are a class of chemicals of emerging concern. However, little is known about the environmental behavior, transformation and ecological risk of OPEs in mid-latitude glacial...
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Agricultural land-use system management: research progress and perspectives
Available online 4 November 2024
The agricultural land-use system (ALUS) is a complex and coupled system centered on land use, which includes all human activities and their outcomes in utilizing agricultural land. With the emergence...
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Bioavailability factor for improved drinking water contaminant exposure risk assessment accuracy
Available online 1 November 2024
Despite being low in concentration, the presence of broad-spectrum chemical constituents in drinking water is a fact of modern life. The current drinking water chemical risk assessment practice predominantly...
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Optimizing Expertise Management in Crowdsourcing Contests: The Impact of Information Structures on Open Innovation Efficiency
Available online 28 October 2024
For companies and governments alike, crowdsourcing contests have emerged as a popular approach to harness the benefits of open innovation. Consequently, numerous game models have been developed to analyze...
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Unraveling urban dynamics: Scaling laws of human mobility across the cityscape divide
Available online 26 October 2024
•This study introduces an innovative analytical framework to explore the nexus between collective travel demand and city population dynamics. we uncover segmented allometric scaling in human mobility...
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Impact of resource availability and conformity effect on sustainability of common-pool resources
Available online 24 October 2024
Sustainability of common-pool resources hinges on the interplay between human and environmental systems. However, there is still a lack of a novel and comprehensive framework for modelling extraction...
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Contrasting foliar nitrogen nutrition of coexisting temperate and boreal trees across a modest temperature cline
Available online 18 October 2024
The temperate-boreal forest ecotone represents a transition zone from temperate to boreal forest where nitrogen (N) is frequently limiting tree growth. However, the spatial patterns and potential drivers...
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Pre-implantation embryo metabolism identified by PEMA reveals endogenous lactate insufficiency contributes to pre-implantation development arrest
Available online 18 October 2024
Metabolism is a major regulator of pre-implantation embryonic development, but pre-implantation development arrest (PIDA) due to abnormal metabolisms remains ambiguous. By estimating a weight for each...
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Progress in Cellular Mechanisms of Chronic Rhinosinusitis
Available online 16 October 2024
Chronic rhinosinusitis (CRS) represents one of the most common chronic conditions occurring in the nasal cavity and sinuses, affecting approximately 10% of the global population and imposing a significant...
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Terahertz channels in atmospheric conditions: Propagation characteristics and security performance
Available online 16 October 2024
With the growing demand for higher wireless data rates, the interest in extending the carrier frequency of wireless links to the terahertz (THz) range has significantly increased. For long-distance...
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The implementation of ecological protection in Inner Mongolia has slowed down grassland degradation
Available online 16 October 2024
The Inner Mongolia grassland has been facing critical degradation. To combat this issue, China has launched a series of ecological restoration programs since the early 2000s to promote the recovery...
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Open Science Readiness Index: Theory and Simulations
Available online 15 October 2024
An Open Science Readiness Index (abbreviated as OSRI) is proposed to quantify the progression of open science. The index is accumulated by three related but separately measured dimensions: the readiness...
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Can software-defined vehicles never roll over: A perspective of active structural transformation
September 2024
•A coupled motion model of an active transformable vehicle was established.•The relationship between dynamic performance and adjustable parameters was revealed.•A performance optimization problem supported...
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Construction and evaluation of a polygenic hazard score for prognostic assessment in localized gastric cancer
September 2024
To investigate whether genetic variants may provide additional prognostic value to improve the existing clinical staging system for gastric cancer (GC), we performed two genome-wide association studies...
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