Integrating proteomics and targeted metabolomics to reveal the material basis of liver-gallbladder damp-heat syndrome in chronic hepatitis B
December 2024
To elucidate the biological basis of liver-gallbladder damp-heat syndrome (LGDHS) within the framework of traditional Chinese medicine (TCM) as a complementary diagnostic and therapeutic approach in...
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Classification of cold and hot medicinal properties of Chinese herbal medicines based on graph convolutional network
December 2024
To develop a model based on a graph convolutional network (GCN) to achieve efficient classification of the cold and hot medicinal properties of Chinese herbal medicines (CHMs)....
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Uric acid-lowering activity and mechanisms of Chinese medicines with medicine-food homology: a systematic study
December 2024
To summarize the uric acid-lowering effects and mechanisms of Chinese medicines with medicine-food homology, aiming to provide novel perspectives for the development of new anti-hyperuricemia (HUA)...
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TCMLLM-PR: evaluation of large language models for prescription recommendation in traditional Chinese medicine
December 2024
To develop and evaluate a fine-tuned large language model (LLM) for traditional Chinese medicine (TCM) prescription recommendation named TCMLLM-PR....
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Risk assessment of coronary artery occlusion based on integrated Chinese and western medicine data
December 2024
To develop an integrated risk model for coronary artery occlusion based on data of both traditional Chinese medicine (TCM) and western medicine data, and to evaluate the contribution of TCM-specific...
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Study on the facial spectrum and color characteristics of patients with essential hypertension
December 2024
To investigate the facial spectrum and color characteristics of patients with essential hypertension post administering antihypertensive drugs, establish a classification and evaluation model based...
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Research progress in Fangjiomics: methodologies, applications, and perspectives
December 2024
Fangjiomics is a promising paradigm that enhances research on multi-omics-based pharmacological mechanisms of Fangji from holistic and systematic perspective. We reviewed recent advances in Fangjiomics,...
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Recent advancements in digital and traditional treatment strategies for major depressive disorder using medicinal herbs
December 2024
Integrating digital health technologies, including mobile applications and digital biomarkers, with traditional medicinal plants and phytochemicals may enhance the effectiveness of standard antidepressants....
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Harnessing traditional herbal medicine: molecular insights into diabetic wound healing for modern therapeutics
December 2024
This study aims to explore the molecular aspects of the wound-healing potential of medicinal plants through preclinical and clinical research. This review focuses on the theoretical support and therapeutic...
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The modulating of Qingguang’an II Formula on gut microbiota in mice with chronic high intraocular pressure by 16S rDNA sequencing
December 2024
To investigate the effects of Qingguang'an II Formula (QGA II) on the gut microbiota of mice with chronic high intraocular pressure (IOP) model, and explore its key microbiota for protecting the optic...
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Lightweight and polarized self-attention mechanism for abnormal morphology classification algorithm during traditional Chinese medicine inspection
September 2024
To propose a Light-Atten-Pose-based algorithm for classifying abnormal morphology in traditional Chinese medicine (TCM) inspection to solve the problem of relying on manual labor or expensive equipment...
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Metabolic characteristics of Qi-Yin deficiency and heat stagnation in liver meridian patterns of dry eye based on tear metabolomics
September 2024
To explore the metabolic differences between dry eye patients with Qi-Yin deficiency and heat stagnation in liver meridian patterns, and clarify their metabolic characteristics....
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A Rumsfeld Matrix test for acupuncture clinical trials
September 2024
This study examined the application of the Rumsfeld Matrix to acupuncture clinical trials, particularly those published in leading medical journals such as The Journal of the American Medical Association...
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Effects of needling at Sanyinjiao (SP6) acupuncture point on blood glucose levels and cardiovascular functions in patients with type 2 diabetes mellitus: a randomized placebo-controlled study
September 2024
To determine the effect of needling at Sanyinjiao (SP6) on random blood glucose (RBG) levels and cardiovascular function in patients with type 2 diabetes mellitus (T2DM)....
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A novel method for integrating chromatographic fingerprint analytical units of Chinese materia medica: the matching frequency statistical moment method
September 2024
To facilitate the quality evaluation suitable for the unique characteristics of Chinese materia medica (CMM) by developing and implementing a novel approach known as the matching frequency statistical...
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Analysis on pulse features of coronary heart disease patients with or without a history of ischemic stroke
September 2024
To evaluate the capability of wrist pulse analysis in distinguishing three physiological and pathological conditions: healthy individuals, coronary heart disease (CHD) patients without a history of...
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The gas discharge visualization (GDV) order parameter model based on the principle of mastering both permanence and change
September 2024
To investigate the human body’s complex system, and classify and characterize the human body’s health states with “a comprehensive integrated method from qualitative to quantitative”....
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Construction and optimization of traditional Chinese medicine constitution prediction models based on deep learning
September 2024
To cater to the demands for personalized health services from a deep learning perspective by investigating the characteristics of traditional Chinese medicine (TCM) constitution data and constructing...
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Modulation of synaptic damage by Bushen Tiansui Decoction via the PI3K signaling pathway in an Alzheimer’s disease model
September 2024
To explore the therapeutic effect and mechanism of Bushen Tiansui Decoction (补肾填髓方, BSTSD) and its active component icariin on Alzheimer’s disease (AD)....
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Deep learning-based recognition of stained tongue coating images
June 2024
To build a dataset encompassing a large number of stained tongue coating images and process it using deep learning to automatically recognize stained tongue coating images....
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Tongue image feature correlation analysis in benign lung nodules and lung cancer
June 2024
To analyze the differences in the correlation of tongue image indicators among patients with benign lung nodules and lung cancer....
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Study on the interaction between volatile oil components and skin lipids based on molecular docking techniques
June 2024
To analyze the interactions between different structural types of volatile oil components (VOCs) and skin lipid molecules, and investigate the mechanism of volatile oil in Chinese materia medica (VOCMM)...
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Unveiling osteoprotective potential of biologically active naringenin in rats with dexamethasone-induced osteoporosis
June 2024
To investigate the protective effects of naringenin (NRG) against dexamethasone (DEX)-induced osteoporosis (OP) in rats....
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An interpretability model for syndrome differentiation of HBV-ACLF in traditional Chinese medicine using small-sample imbalanced data
June 2024
Clinical medical record data associated with hepatitis B-related acute-on-chronic liver failure (HBV-ACLF) generally have small sample sizes and a class imbalance. However, most machine learning models...
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Integrative analysis of bone-formation associated genes and immune cell infiltration in osteoporosis, and the prediction of active ingredients in targeted traditional Chinese medicine
June 2024
To explore the differential expression and mechanisms of bone formation-related genes in osteoporosis (OP) leveraging bioinformatics and machine learning methodologies, and to predict the active ingredients...
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