The principal aim of Current Proteomics is to publish well-timed in-depth/mini review articles in this fast-expanding area on topics relevant and significant to the development of proteomics. Current Proteomics is an essential journal for everyone involved in proteomics and related fields in both academia and industry.

All areas of proteomics are covered together with the methodology, software, databases, technological advances and applications of proteomics, including functional proteomics. Diverse technologies covered include but are not limited to:2-D gel electrophoresis and image analysis,Analysis of protein complexes,Biomolecular interaction analysis,Determination of co-translational and post- translational modification of proteins,High-throughput computational methods for protein 3-D structure as well as function determination,High-throughput protein structural studies (using mass spectrometry, nuclear magnetic resonance and X-ray crystallography),Knowledge integration and management tools,Protein separation and characterization techniques,Protein/peptide microarrays,Protein-protein interaction (protein interactome) pathways and cell signaling networks,Proteome informatics (bioinformatics),Robotics, nanotechnology, and microfluidics,Systems biology,Techniques for protein expression profiling including mass spectrometry-based methods and algorithms for correlative database searching,Yeast two-hybrid projects,In addition to in-depth/mini reviews, articles highlighting recent proteomics papers of special interest as well as book reviews are published. In view of the importance of specific technology and software developed for advancement of proteomics research, a separate section is devoted to product and technology reports. Proceedings of proteomics meetings with selected review articles on topics presented are also published.

This journal contains four sections:

Section A（Protein & Protein Modifications & Proteomics）: This section provides a comprehensive overview of protein expression profiling, complex structural and functional analyses, and detailed investigations of post-translational modifications, including ubiquitination, phosphorylation, glycosylation, nitrosylation, acetylation, and lipidation. It introduces a series of novel acylation modifications, such as succinylation, crotonylation, 2-hydroxyisobutyrylation, and lactylation, also introduces the combined analysis of proteomics and multi-genomics. Additionally. Furthermore, it explores protein alterations related to vascular function, intercellular communication mechanisms, and cellular phenotypic hotspots, including non-programmed cell death, autophagy, and cellular senescence. The discussion extends to tissue biochemical adaptations, subcellular structural functions, and metabolic reprogramming processes, such as glycolysis, oxidative phosphorylation, fatty acid metabolism, and amino acid metabolism.

Section B (Drug Proteomics) : This section focuses on the study of drug-protein interactions, encompassing target identification, mechanisms of action, and assessments of drug efficacy through the use of proteomics technologies to screen and evaluate new drugs. Furthermore, it explores proteomics-based drug development strategies by analyzing alterations in disease-related proteins to identify new drug targets and design drugs that specifically target these proteins.

Section C (Molecular & Cellular Proteomics): The section is study the development and application of protein omics in basic and transformation research, and to report important new biological or clinical findings.Scope:Fundamental studies in biology, including integrative "omics" studies, that provide mechanistic insights;Proteogenomic data integration and analysis that enable greater understanding of physiology and disease processes ; Pathway and network analyses of signaling that focus on the roles of post-translational modifications ; Studies of proteomics dynamics and quality controls, and their roles in disease；Studies of evolutionary processes effecting proteomics dynamics, quality and regulation;Chemical proteomics;Proteomics of the immune system and antigen presentation/recognition;Microbiome proteomics, host-microbe and host-pathogen interactions, and their roles in health and disease.It involves the influence of epigenetic modification of DNA dimension on gene expression, the role of mRNA in transcription and translation, and the key role of noncoding RNA in the regulation of protein expression.

Section D (Clinical Proteomics):Clinical Proteomics encompasses all aspects of translational proteomics, Special emphasis will be placed on the application of proteomic technology to all aspects of clinical research and molecular medicine. Post-translational modification proteomics is a sub-field of proteomics，Specially study the types, positions and dynamic changes of protein post-translation modifications,expand the functional diversity of protein and play a key role in many biological processes, such as signal transduction, gene expression regulation, protein degradation and so on.

Editorial Board