Nanotechnology based electrochemical (bio)sensors for insulin/hormone sensing
February 2025
Insulin is an essential biomarker, mainly found in the bloodstream and controls carbohydrate metabolism. Biosensors are contemporary engineering vehicles that can be usually employed for assorted technological...
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Nutraceuticals potential of Zingiber officinale and Linum usitatissimum: A comprehensive analysis of macroscopic, microscopic, physico-chemical and phyto-chemical properties
February 2025
Ginger (Zingiber officinale) and flaxseed (Linum usitatissimum) demonstrate a diverse spectrum of anti-inflammatory and antioxidant properties, with therapeutic applications in integrative medicine,...
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Bioinformatic methods uncover 5 diagnostic biomarkers associated with drug resistance and metastasis for gastrointestinal stromal tumor
February 2025
Gastrointestinal stromal tumor (GIST) is a prevalent neoplasm in digestive tract, drug resistance and metastasis remain the major challenges during treatment. This work commenced to identify novel diagnostic...
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The role of Ursolic acid, a pharmacologically active compound from Ocimum sanctum L. as a potential chemotherapeutic agent
February 2025
The global cancer burden is predicted to rise by 40 % around the year 2030. Cancer-related mortality is exacerbated by the fact that the disease is becoming increasingly resistant to standard treatments....
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Integrated Lipidomics and Computational Analyses Reveal Cardiolipin Dysregulation as a Therapeutic Target in Bortezomib-Induced Peripheral Neuropathy
Available online 15 February 2025
Multiple myeloma (MM) is a prevalent hematological malignancy characterized by aberrant plasma cell proliferation. Bortezomib (BTZ) is a first-line therapy for MM but frequently induces peripheral neuropathy...
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Impurity Profiling and Forced Degradation Studies of Angiotensin (AT1) Blockers: A Review
Available online 12 February 2025
This review looks at the latest developments in some analytical techniques employed for impurity profiling and forced degradation studies for sartans, or angiotensin (AT1) receptor blockers, which are...
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Therapeutic potential of natural products in stress granules: underlying molecular mechanisms and future perspectives
Available online 4 February 2025
Stress granules (SGs) are non-membranous structures that form in response to various cellular stress conditions. Natural compounds, derived from plants, animals, microorganisms, and marine organisms,...
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A systematic and comprehensive review of the properties and synthesis of anticancer heterocyclic natural products
Available online 18 January 2025
Heterocyclic natural products are abundant in variety and have useful bioactivities. Cancer, being one of the most widespread sets of potentially lethal diseases, has attracted a great deal of attention...
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Emerging trends and hot topics in the application of multi-omics in drug discovery: A bibliometric and visualized study
December 2024
The application of multi-omics in drug discovery is rapidly advancing, but its trends and hotspots have not been fully analyzed. By reviewing key achievements and research hotspots in this field, the...
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Advances in drug discovery based on network pharmacology and omics technology
December 2024
Drug discovery plays a crucial role in cancer treatment. Traditional drug discovery methods mainly rely on in vivo animal experiments and in vitro drug screening, which are not only costly but also...
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Advancing pharmaceutical research: A comprehensive review of cutting-edge tools and technologies
December 2024
This comprehensive review investigates the cutting-edge tools and technologies that are revolutionizing modern pharmaceutical research. We analyze the integration of artificial intelligence and machine...
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