Organ-on-chip technology: Opportunities and challenges
2024
Organ-on-chip (OOC) technology is an innovative approach that reproduces human organ structures and functions on microfluidic platforms, offering detailed insights into intricate physiological processes....
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A comprehensive study on anaerobic digestion of organic solid waste: A review on configurations, operating parameters, techno-economic analysis and current trends
2024
The excessive discharge and accumulation of solid organic waste into the environment is of severe concern across the globe. Thus, an efficient waste management system is important to mitigate health...
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Decoding dye degradation: Microbial remediation of textile industry effluents
2023
The extensive use of chemical dyes, primarily Azo and anthraquinone dyes, in textiles has resulted in their alarming release into the environment by textile industries. The introduction of heavy metals...
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Green synthesis and characterization of iron nanoparticles synthesized from bioflocculant for wastewater treatment: A review
2025
Nanotechnology is a rapidly expanding field with diverse healthcare, agriculture, and industry applications. Central to this discipline is manipulating materials at the nanoscale, particularly nanoparticles...
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The potential of copper oxide nanoparticles in nanomedicine: A comprehensive review
2024
Nanotechnology is a modern scientific discipline that uses nanoparticles of metals like copper, silver, gold, platinum, and zinc for various applications. Copper oxide nanoparticles (CuONPs) are effective...
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Ribosome purification from Escherichia coli by ultracentrifugation
2022
With more and more researchers conducting extensive research on all aspects of ribosomes, how to extract ribosomes with good effect and high activity has become a fundamental problem. In this article,...
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Unlocking the potential of biosurfactants: Innovations in metabolic and genetic engineering for sustainable industrial and environmental solutions
2024
Biosurfactants, synthesized by microorganisms, hold potential for various industrial and environmental applications due to their surface-active properties and biodegradability. Metabolic and genetic...
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The future of cell-free synthetic biology
2024
Cell-free synthetic biology aims at the targeted replication, design, and modification of life processes in open systems by breaking free of constraints such as cell membrane barriers and living cell...
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The role of Micro-biome engineering in enhancing Food safety and quality
2025
Microbiome engineering has emerged as a transformative approach to enhancing food safety and quality by strategically modulating microbial communities. This review critically examines state-of-the-art...
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Circular mRNA: A novel therapeutic agent
2023
Circular mRNA (circmRNA) is a covalent closed loop formed by reverse splicing of the 3′ end to the 5′ end of mRNA. Compared to traditional linear mRNAs, circmRNAs can mediate efficient, stable, and...
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Development of destabilized mCherry fluorescent proteins for applications in the model yeast Saccharomyces cerevisiae
2022
Fluorescent proteins are widely used molecular reporters in studying gene expression and subcellular protein localization. To enable the monitoring of transient cellular events in the model yeast Saccharomyces...
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Synthetic biology in Europe: current community landscape and future perspectives
2022
Synthetic biology has captivated scientists' imagination. It promises answers to some of the grand challenges society is facing: worsening climate crisis, insufficient food supplies for ever growing...
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Effect of temperature and CO2 concentration on biological nutrient removal from tertiary municipal wastewater using microalgae Chlorella prototheocoides
2025
This study investigates the potential of phototrophic microalgae, specifically Chlorella protothecoides, for biological wastewater treatment, with a focus on the effects of air temperature and CO2 concentration...
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Microbial amidases: Characterization, advances and biotechnological applications
2025
The amidases (EC 3.5.1.4) are versatile hydrolase biocatalysts that have been the attention of academia and industries for stereo-selective synthesis and bioremediation. These are categorized based...
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Unraveling current breakthroughs in Scorodocarpus borneensis phytochemical therapeutics: A systematic review
2024
Scorodocarpus borneensis, also known as the Kulim tree or Garlic tree, has been consumed by the local communities in Southeast Asia as traditional spice using its old leaves, stem bark, and seeds. The...
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A comparative exploration of mRNA capping enzymes
2024
With the wide application of messenger RNA (mRNA) technology in medicine and vaccine fields, higher requirements are put forward for mRNA expression efficiency in vivo. Since the 5′ cap structure can...
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Hyperuricemia and the small intestine: Transport mechanisms and co-morbidities
2022
There is a global increase in cases of hyperuricemia over the last 10 years. A critical component of serum uric acid control is the transport of uric acid to the intestinal lumen, which accounts for...
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Synthetic biology in Indonesia: Potential and projection in a country with mega biodiversity
2023
Synthetic biology has gained many interest around the globe in the last two decades, not only due to its rapid development but also the potential to provide addressable solutions using standardized...
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Cell-free protein synthesis platforms for accelerating drug discovery
2025
Cell-free protein synthesis is a platform for streamlined production of macromolecules. Recently, several proteins with pharmaceutical relevance were synthesised and characterised. Off-the-shelf reagents...
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Exploration on the expression and assembly of virus-like particles
2021
Virus-like particles (VLPs) have a great application prospect in vaccines and molecule delivery carriers. In this study, in order to solve the problem of low expression and low assembly efficiency of...
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Incorporating omics-based tools into endophytic fungal research
2024
Fungal endophytes are valuable sources of bioactive compounds with diverse applications. The exploration of these compounds not only contributes to our understanding of ecological interactions but also...
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Construction of an ultra-strong PtacM promoter via engineering the core-element spacer and 5′ untranslated region for versatile applications in Corynebacterium glutamicum
2022
As one of the most important synthetic biology elements in transcriptional regulation, promoters play irreplaceable roles in metabolic engineering. For the industrial microorganism Corynebacterium glutamicum,...
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Deciphering Rickettsia conorii metabolic pathways: A treasure map to therapeutic targets
2025
Indian tick typhus is an infectious disease caused by intracellular gram-negative bacteria Rickettsia conorii (R. conorii). The bacterium is transmitted to humans through bite of infected ticks and...
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Therapeutic advancements in nanomedicine: The multifaceted roles of silver nanoparticles
2024
Nanotechnology has the advantages of enhanced bioactivity, reduced toxicity, target specificity, and sustained release and NPs can penetrate cell membranes. The small size of silver nanoparticles, AgNPs,...
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Understanding virus retention mechanisms on protein a chromatography based on using different wash buffers – Evaluating the possibility for a generic wash buffer toolbox to improve virus clearance capacity
2024
During manufacturing of mammalian-cell derived monoclonal antibodies (mAbs) virus clearance capacity of the downstream process has to be demonstrated. The protein A chromatography step typically achieves...
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