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ISSN: 2949-723X

Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment

This review evaluates the literature on nanoparticle-based drug delivery systems for cancer treatment and assesses their efficacy. Nanoparticles have shown potential for improving anticancer agent delivery,...

A review on selenium nanoparticles and their biomedical applications

Nanotechnology has enormous promise for a wide range of applications in biology. Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing for precision targeting,...

Nanomaterials for wound healing: Current status and futuristic frontier

Wound healing is a complex process that involves a variety of physical, chemical, and biological processes. Because of their remarkable characteristics and capabilities, nanomaterials have recently...

Exploring the revolution in healthcare systems through the applications of digital twin technology

Digital Twin is a virtual replica of an item that is gaining traction in several sectors. This technology is creating significant advancements in the field of healthcare. A machine or a person's digital...

Emerging strategies for the treatment of endometriosis

Endometriosis is an estrogen-dependent disorder of the reproductive tract, affecting approximately 10 ​% of women. The symptoms of this condition are vague and not correlated with the disease's stage....

Sustaining the healthcare systems through the conceptual of biomedical engineering: A study with recent and future potentials

Biomedical engineering is an interdisciplinary branch of engineering & technology that combines biomedical sciences with engineering principles. This discipline covers broad areas where biomedical engineers...

Advanced 3D biomaterials and bioprinting strategies for in vitro modeling of neurodegenerative diseases

Neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) remain a major global health challenge due...

Acid-labile chemical bonds-based nanoparticles for endosome escape and intracellular delivery

In the last years there has been a booming in the development of biological pharmaceuticals, and various nanoparticle delivery systems have been developed to overcome biological barriers to maximize...

Improved efficacy with early tocilizumab in the prophylaxis and treatment of cytokine release syndrome of chimeric antigen receptor T cell (CAR-T) therapy for diffuse large B-cell lymphoma than acute lymphoblastic leukemia

Tocilizumab is a well-practiced strategy to manage cytokine release syndrome (CRS) after chimeric antigen receptor T cell (CAR-T) therapy. However, varied efficiency in CRS mitigation by tocilizumab...

Superparamagnetic hydrogels: Precision-driven platforms for biomedicine, robotics, and environmental remediation

Hydrogels are widely recognized for their biocompatibility and structural adaptability in regenerative medicine and three-dimensional (3D) bioprinting, yet their inherent static nature fundamentally...

Application of gas molecules in cancer therapy

Gas therapy is currently popular in cancer treatment because of its controllability, effectiveness, and biosafety, as well as the fast development of carriers for gas delivery. Here, we introduce the...

A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment

Carbon quantum dots (CQDs) are an emerging class of carbon-based nanomaterials. CQDs are receiving considerable interest in biomedical applications due to their low toxicity, stability profile, efficient...

HFF-Net: A hybrid convolutional neural network for diabetic retinopathy screening and grading

Diabetic Retinopathy (DR) is a leading cause of vision loss among diabetic patients, necessitating effective screening and grading for timely intervention. Regular screening significantly increases...

Effect of orthotic insole on symptomatic flexible flatfoot in school-age children: Meta-analysis and 1-year follow-up study

This study aimed to investigate the efficacy of orthopedic insoles, specifically three-dimensional (3D)-printed orthopedic insoles, for treatment of symptomatic flexible flatfoot in school-age chil...

A comprehensive review of cancer drug nanoparticles synthesis, processing technology and its effect in drug delivery

The advent of nanotechnology has significantly advanced cancer treatment by introducing innovative approaches to targeted drug delivery and enhanced therapeutic efficiency. Nano drugs and nanocarriers,...

Biomaterials that passively and actively target macrophages promote the regeneration of injured tissues

Modulation of the immune system has gained significant attention in regenerative medicine. Although most tissues possess intrinsic self-repair capabilities, large-sized defects and complex pathological...

Living probiotic biomaterials for osteoporosis therapy

Osteoporosis (OP) is a chronic metabolic bone disease characterized by diminished bone mass, decreased bone strength, deterioration of bone microarchitecture, and increased bone fragility with fracture...

Biomaterials for cardiovascular diseases

Cardiovascular disease (CVD) remains a leading cause of mortality worldwide, claiming countless lives and posing a formidable health challenge. Extensive efforts have been dedicated to combating this...

Antibacterial hydrogels for bacteria-infected wound treatment

Bacteria-infected wounds are enormous clinical obstacles and cause huge burdens to patients and society. Recently, many biomaterials are designed to treat bacterial infected wounds. Among various biomaterials,...

Functional hydrogels for treatment of dental caries

As the most popular teeth problem, dental caries can result in pain, suffering, impaired function, and diminished quality of life among communities, which calls for new strategies to improve the therapeutic...

Targeting HSPA8 to repress GPX4 and induce ferroptosis in BCR-ABL positive leukemia

BCR-ABL positive (BCR-ABL+) leukemia is driven by constitutive activation of tyrosine kinase activity, with tyrosine kinase inhibitors (TKIs) serving as the standard treatment. However, resistance to...

Injectable hydrogel microspheres in cartilage repair

The key to regenerative medicine is in situ regeneration of lesion cells, so as to achieve lesion repair and regeneration. However, the complex environment of the joint cavity where cartilage is located...

Integrated bioinformatics analysis and machine learning approach for the identification of immune-related genes in the diagnosis of aortic valve calcification with periodontitis

Aortic valve calcification (AVC) represents a progressive, age-associated disorder characterized by substantial mortality, yet effective early diagnostic markers for AVC complicated by periodontitis,...

Bio-inspired adhesive hydrogel for wound healing

Wound healing introduces a series of interesting challenges in healthcare, such as open wounds, burn wounds, and chronic infection wounds. Hence more accurate and effective biomedical materials are...

Applications of 3D printing in tumor treatment

As an emerging technology relevant to materials science, 3D printing technology simplifies material production process, shortens the preparation cycle, and provides a broader space for disease treatment....

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