Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review
January 2025
This review paper explores the cutting-edge advancements in hydrogel design for articular cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence worldwide that can lead...
Dynamic compliance penis enlargement patch
December 2024
Men are particularly sensitive to penis size, especially those with a deformed or injured penis. This can lead to a strong desire for penis enlargement surgery. Given the ethical sensitivities of the...
Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration
September 2023
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its non-invasiveness, painless and simple administration, controllable drug delivery, and diverse cargo loading...
Bone grafts and biomaterials substitutes for bone defect repair: A review
December 2017
Bone grafts have been predominated used to treat bone defects, delayed union or non-union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency of synthetic bone graft...
AI-enabled organoids: Construction, analysis, and application
January 2024
Organoids, miniature and simplified in vitro model systems that mimic the structure and function of organs, have attracted considerable interest due to their promising applications in disease modeling,...
Dental pulp regeneration strategies: A review of status quo and recent advances
August 2024
Microorganisms, physical factors such as temperature or mechanical injury, and chemical factors such as free monomers from composite resin are the main causes of dental pulp diseases. Current clinical...
Developing natural polymers for skin wound healing
March 2024
Natural polymers are complex organic molecules that occur in the natural environment and have not been subjected to artificial synthesis. They are frequently encountered in various creatures, including...
AI-driven 3D bioprinting for regenerative medicine: From bench to bedside
March 2025
In recent decades, 3D bioprinting has garnered significant research attention due to its ability to manipulate biomaterials and cells to create complex structures precisely. However, due to technological...
Antibacterial conductive self-healing hydrogel wound dressing with dual dynamic bonds promotes infected wound healing
December 2023
In clinical applications, there is a lack of wound dressings that combine efficient resistance to drug-resistant bacteria with good self-healing properties. In this study, a series of adhesive self-healing...
Decellularized extracellular matrix biomaterials for regenerative therapies: Advances, challenges and clinical prospects
February 2024
Tissue engineering and regenerative medicine have shown potential in the repair and regeneration of tissues and organs via the use of engineered biomaterials and scaffolds. However, current constructs...
Advances in orthodontic clear aligner materials
April 2023
Rapid technological improvements in biomaterials, computer-aided design (CAD) and manufacturing (CAM) have endorsed clear aligner therapy (CAT) as a mainstay of orthodontic treatment, and the materials...
Facile fabrication of antioxidative and antibacterial hydrogel films to accelerate infected diabetic wound healing
November 2025
Diabetic wounds are accompanied with hemorrhage, excessive reactive oxygen species accumulation, microbial infection, and poor exudate management. Current dressings are insufficient to modulate the...
A tough, antibacterial and antioxidant hydrogel dressing accelerates wound healing and suppresses hypertrophic scar formation in infected wounds
April 2024
Wound management is an important issue that places enormous pressure on the physical and mental health of patients, especially in cases of infection, where the increased inflammatory response could...
Embedded 3D bioprinting – An emerging strategy to fabricate biomimetic & large vascularized tissue constructs
February 2024
Three–dimensional bioprinting is an advanced tissue fabrication technique that allows printing complex structures with precise positioning of multiple cell types layer–by–layer. Compared to other bioprinting...
Engineered bacteria and bacteria-derived nanomaterials for cancer therapy: Mechanisms, designs and advances
January 2026
Bacteria have emerged as powerful and versatile platforms for cancer therapy, leveraging their inherent tumor-targeting capabilities, adaptability to engineering, and ability to interact dynamically...
Peptide-based nanomaterials: Self-assembly, properties and applications
May 2022
Peptide-based materials that have diverse structures and functionalities are an important type of biomaterials. In former times, peptide-based nanomaterials with excellent stability were constructed...
Hydrogel scaffold encapsulating MSC-Exos and ZIF-8 promotes bone regeneration via coordinating osteogenesis and immunomodulation
December 2025
The limited bone regeneration and suboptimal immune responses constitute the major challenges in repairing critical-sized bone defects. As an emerging therapeutic modality, mesenchymal stem cell-derived...
Keratin - Based materials for biomedical applications
September 2020
Keratin constitutes the major component of the feather, hair, hooves, horns, and wool represents a group of biological material having high cysteine content (7–13%) as compared to other structural proteins....
Advances in medical devices using nanomaterials and nanotechnology: Innovation and regulatory science
June 2025
Nanomaterials and nanotechnology are emerging as promising strategies for medical devices due to their advantageous properties, including the ability to effectively interact with biomolecules and tissues,...
Extracellular matrix-derived materials for tissue engineering and regenerative medicine: A journey from isolation to characterization and application
April 2024
Biomaterial choice is an essential step during the development tissue engineering and regenerative medicine (TERM) applications. The selected biomaterial must present properties allowing the physiological-like...
Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery
November 2025
As an innovative physiotherapeutic approach, magnetic hyperthermia therapy (MHT) has unique advantages including minimal invasiveness, precise temperature control, and deep tissue penetration capabilities....
An overview of filtration efficiency through the masks: Mechanisms of the aerosols penetration
January 2021
The masks have always been mentioned as an effective tool against environmental threats. They are considered as protective equipment to preserve the respiratory system against the non-desirable air...
A combination therapy for androgenic alopecia based on quercetin and zinc/copper dual-doped mesoporous silica nanocomposite microneedle patch
June 2023
A nanocomposite microneedle (ZCQ/MN) patch containing copper/zinc dual-doped mesoporous silica nanoparticles loaded with quercetin (ZCQ) was developed as a combination therapy for androgenic alopecia...
Sterilization and disinfection methods for decellularized matrix materials: Review, consideration and proposal
September 2021
Sterilization is the process of killing all microorganisms, while disinfection is the process of killing or removing all kinds of pathogenic microorganisms except bacterial spores. Biomaterials involved...
3D printing of chitosan hydrogel reinforced with tubular nanoclay for hemostasis and infected wound healing
December 2025
Developing hydrogel dressings capable of rapid hemostasis and accommodating irregular wounds is crucial for infected wound healing. Customizable 3D-printed hydrogels, highly sought after for wound management,...
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