Role of cognitive computing in enhancing innovative healthcare solutions
2024
Cognitive computing represents a groundbreaking development in healthcare, encompassing technological platforms that emulate the human brain's functionality. While cloud computing offers on-demand internet...
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Leveraging lean 4.0 technologies in healthcare: An exploration of its applications
2024
Lean 4.0, a fusion of lean manufacturing and digital technologies, is a powerful tool for implementing Industry 4.0. Its widespread use across sectors is driven by its ability to eliminate waste, reduce...
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Influence of deproteinization and demineralization process sequences on the physicochemical and structural characteristics of chitin isolated from Deep-sea mud shrimp (Solenocera hextii)
2022
Isolation of chitin from shrimp shell waste using chemical process is a well-adopted industrial practice due to its short process time and efficiency in removing both minerals and proteins from the...
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A brief history of urine examination - From ancient uroscopy to 21st century urinomics
2024
The art of uroscopy (Greek ouron-urine and skopeo-examination), the visual inspection of urine, is as old as the history of mankind. It had seen its ups and downs, was praised and derided, but was ultimately...
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The effects of machine learning algorithms in magnetic resonance imaging (MRI), and biomarkers on early detection of Alzheimer's disease
2024
Alzheimer's Disease (AD) is a disorder that worsens over time causing loss of memory and decline of cognitive functions. Current methods for diagnosis consist of neuroimaging scans, magnetic resonance...
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Transforming early microbial detection: Investigating innovative biosensors for emerging infectious diseases
2024
The recent global pandemic has highlighted an increase in the prevalence of communicable diseases caused by pathogens. The swift transmission of these diseases within a short timeframe presents a substantial...
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Chemical fingerprint of Centella Asiatica’s bioactive compounds in the ethanolic and aqueous extracts
2020
Centella asiatica is a herbal plant that is widely used as medicine due to the benefit of its bioactive compounds such as rutin, kaempferol, quercetin, gallic acid, luteolin and catechin. Typically,...
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Faecal microbial transplant
2024
Faecal Microbial Transplantation (FMT), have been shown to be successfully managed along with a variety of gastrointestinal disorders, including Clostridioides difficile infection (CDI), inflammatory...
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Association of vitamin B12 and vitamin D in T2DM patients in north Indian population
2024
Diabetes mellitus, highly prevalent endocrine disorder and metformin is the most frequently recommended oral hypoglycemic agent (OHA)....
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Matrix metalloproteinase 7 as a diagnostic biomarker of biliary atresia: A systematic review
2024
Biliary atresia (BA) is a disease of the intrahepatic or extrahepatic bile ducts with an unknown etiology. It presents in neonates with jaundice, clay-colored stool, and often hepatomegaly. Early diagnosis...
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Nanomedicine in cancer therapy: Advancing precision treatments
2024
The progress made in the field of nanotechnology has resulted in the development of nanomedicine agents, which have demonstrated their efficacy as a promising clinical tool in the fight against different...
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Inflammation-induced cellular changes: Genetic mutations, oncogene impact, and novel glycoprotein biomarkers
2024
Persistent inflammation can trigger the development of colorectal cancer, especially in patients with inflammatory bowel disease (IBD). The precise molecular mechanisms underlying this process are not...
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Isolation and characterization of cytotoxic and antioxidant biomarkers from the aerial parts of Suaedaaegyptica
2024
Chronic disease is an irregular change inside or outside of the tissues and organs that results in accumulation, local damage, and inflammation or irritation. Suaeda aegyptiaca (S. aegyptiaca) is a...
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Antioxidant and antibacterial activities of leaves crude extracts of Adenium obesum grown in Oman National Botanical Garden
2021
Globally, researchers are investigated and recommend that about two-thirds of the plant and marine species available have significant antioxidant and antibacterial activities. Plant reduce oxidative...
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Diagnostic performance of point-of-care ubiquitin carboxy-terminal Hydrolase-L1 assay in distinguishing imaging abnormalities in traumatic brain injury: A TRACK-TBI cohort study
2023
The use of UCH-L1 detection with point-of-care (POC) assay alone has not been characterized for clinical use. This study compares the accuracies of POC UCH-L1 and Neuron-Specific Enolase (NSE) Elecsys®...
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The role of obesity on chronic kidney disease development, progression, and cardiovascular complications
2020
The complex links between obesity, chronic kidney disease (CKD) and cardiovascular disease (CVD) are not completely understood. The objective of this review is to describe and discuss the anatomy, physiology,...
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Therapeutic potential of black seed oil in treating rheumatoid arthritis: Insights on biochemical and genetic analyses of inflammatory signaling transducer
2024
Nigella sativa (Black seed) has been a longstanding component of traditional medicine. Rheumatoid arthritis, an autoimmune disorder targeting bone, cartilage, and synovial cells, leads to enduring joint...
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Exploring fucosylation in lung cancer: Mechanisms, diagnosis, and therapeutic strategies
2024
Lung cancer remains a global health crisis, responsible for significant morbidity and mortality. Late-stage diagnosis often limits treatment options and patient survival. Therefore, identifying reliable...
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Taurine as a biomarker for aging: A new avenue for translational research
2023
The physiologic and irreversible process of ageing is accompanied by a wide range of structural and functional shifts at multiple different levels. It is also suggested that variations in the blood...
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A systematic study on key Epigenetic modulators in post-stroke conditions
2024
A stroke is a medical emergency characterized by the sudden interruption of blood flow to the brain, leading to cell death from oxygen deprivation. As a leading cause of mortality and long-term disability...
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Isolation and evaluation of significant antibacterial fraction of methanol and its derived fractions from the leaves extract of Zygophyllum simplex
2023
Food poisoning related to bacterial contamination is the most common disease and cause of death nowadays in developing countries. There are many plants that have made a revolution in the field of medicine....
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Paper based molecularly imprinted SERS substrate for early detection of lysophosphatidic acid in ovarian cancer
2024
The current study is related to fabrication of point-of-care molecularly imprinted paper-based analytical devices, specifically related to ovarian cancer early stage detection. The task involves creating...
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Investigation of cystine as differential diagnostic biomarker between astrocytomas and oligodendrogliomas based on global- and targeted analysis using liquid chromatography/tandem mass spectrometric analysis
2023
Astrocytoma and oligodendroglioma are primary brain tumors classified as gliomas. Because there is difference in the prognostic significance of the extent of resection between IDH-mutant astrocytoma...
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Patient-derived primary culture-based prognostic model to predict tumor recurrence in patients with glioma
2024
The prognosis for glioma patients remains grim despite aggressive treatment approaches. Current molecular profiles have limitations in predicting glioma recurrence, highlighting the need for new and...
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Isovalerylglycine and α-Ketobutyrate are novel biomarkers that discriminate clear cell renal cell carcinoma in biopsy specimens using two-dimensional magnetic resonance spectroscopy
2023
Tumor heterogeneity and lack of pre-operative diagnostic biomarkers are key topics in the field of renal cell carcinoma (RCC) identification. Clear cell RCC (ccRCC) is an aggressive cancer subtype which...
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