#AI reads Urine #Associations between maternal urinary volatile organic compounds and child neurocognitive development at two years of age

This study focused on the association between volatile organic compound (VOC) metabolites in pregnant women and the neurocognitive development of their children. Researchers selected 1,023 mother - child pairs, measured the concentrations of 20 VOC metabolites in the urine of pregnant women during three trimesters of pregnancy, and evaluated the neurocognitive development of the children at the age of 2. The results showed that the exposure levels of cyanide, 1,3-butadiene, and acrolein during pregnancy exceeded the safe thresholds in most pregnant women. The concentrations of some metabolites (such as ATCA) were significantly correlated with a decrease in the Mental Development Index scores of boys. Moreover, the mixture of VOC metabolites was also associated with a decrease in the scores of boys, with ATCA contributing the most. The study indicated that exposure to relevant VOCs during pregnancy may affect the neurodevelopment of children, especially male fetuses, and the first trimester of pregnancy is a sensitive period. Further research is needed for confirmation and to implement prevention and control measures.

Environ Health Perspect. 2025 Apr 18. doi: 10.1289/EHP15539.

Youhe Gao

Statement: During the preparation of this work the author(s) used Doubao / AI reading for summarizing the content. After using this tool/service, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the published article.

For earlier AI Reads Urine articles：

https://www.keaipublishing.com/en/journals/advances-in-biomarker-sciences-and-technology/ai-reads-urine/