Mechanisms of exercise against anxiety disorder: A review of the research progress
March 2026
This review aims to explore the efficacy of exercise in the treatment of anxiety disorders and its underlying mechanisms, summarizing recent research advances and focusing on the potential biological...
Impact of the administration type for normobaric hypoxia on the maximal aerobic capacity: A systematic review and meta-analysis
March 2026
Normobaric hypoxia (NH) is a frequent strategy for training under hypoxic conditions that can be administered through different equipment, including face masks or hypoxic chambers/tents. Nonetheless,...
Exercise preconditioning prevents immobilization-induced skeletal muscle atrophy by activating Prmt1-p38/ATF2-Sesn1 signaling axis in C57BL/6J mice
March 2026
This study aimed to explore the effects of a 10-week combined exercise regimen on immobilization-induced muscle atrophy and elucidate the possible function of Protein arginine methyltransferase 1 (Prmt1)...
The effect of exercise rehabilitation on bone mineral density, muscle strength, and physical function outcomes in ACL ruptures: A randomized controlled clinical trial
March 2026
The purpose is to explore the effects of Exercise rehabilitation (ER) on bone mineral density (BMD) of the knee, muscle strength (MS), and physical function (PF) after ACL rupture. Finally, A total...
Mapping the acute trajectory of sport-related concussion outcomes across symptoms, cognition, and blood biomarkers
March 2026
Sport-related concussion (SRC) and its potential neurological sequela represent an emerging global health concern, requiring improved recovery management and strategies for return-to-play (RTP) to enhance...
Comparison of maximal strength, muscle morphology, and motor unit recruitment and firing rate patterns of the abductor digiti minimi in normal-fat and over-fat males
March 2026
This study examined potential differences in strength, muscle morphology, and motor unit (MU) behavior of the abductor digiti minimi (ADM) between normal-fat (NF) and over-fat (OF) males....
Exercise affects salivary biomarkers of creatine metabolism in healthy adults
March 2026
We monitored changes in salivary creatine pre- and post-high-intensity exercise in young adults while also investigating the potential correlation between salivary and serum creatine levels....
Acute effects of medium-frequency electrical energy transfer (TECAR) and transcutaneous electrical nerve stimulation (TENS) on pain and flexibility in athletes with an acute hamstring injury: A randomized controlled trial
March 2026
This study compared the acute effects of electrical energy transfer (TECAR) and transcutaneous electrical stimulation (TENS) on pain and flexibility after a hamstring injury. Young athletes received...
Post-workout supplementation with CoQ10 and sports drink on exercise performance and muscle recovery after exercise in normal and overweight males
March 2026
Post-workout supplementation has been used in athletes and recreational exercisers; however, responses between normal and overweight individuals on exercise performance and muscle recovery are less...
Resilience against exercise-related coronary atherosclerosis: A case study in a master athlete participating in 500 marathons
March 2026
Lifelong endurance exercise is generally associated with cardiovascular health benefits. However, recent studies suggest that prolonged high-volume training may contribute to coronary atherosclerosis,...
Impact of nutrition on long COVID
March 2026
Long COVID is characterized by a group of persistent symptoms following the acute SARS-COV2 infection, which presented a multifaceted challenge to the healthcare systems all over the globe. The long...
Oncorhynchus milt DNA supplementation combined with voluntary exercise alters exercise-related energy substrate utilization of skeletal muscle in mice
Available online 17 February 2026
Lipid utilization is essential for continued exercise. Wheel running is a well-established voluntary exercise, and FAT/CD-36, a fatty acid transporter, is more active during exercise to initiate lipid...
Longer Reaction Time in Peroneal Muscles in Chronic Ankle Instability: Mechanoreceptor Signaling Delay as a Primary Contributor Over Nerve Conduction Prolongation-A cross-sectional cohort study
Available online 12 February 2026
Chronic ankle instability (CAI) is associated with longer peroneal- muscle reaction time (PRT), with two hypotheses explaining its mechanism: (1) delayed mechanoreceptor signaling during sensory encoding,...
Disproportionate declines in physical activity energy expenditure relative to energy intake among Chinese adults: an 18-Year longitudinal study
Available online 4 February 2026
Obesity is commonly conceptualized as a biological consequence of chronic energy imbalance, in which energy intake exceeds energy expenditure. However, population-level evidence directly evaluating...
Leveraging mitochondrial stress to improve healthy aging
January 2026
Aging is characterized by a progressive decline in physiological function, driven by intrinsic mechanisms (primary aging) and modifiable factors (secondary aging), ultimately leading to multimorbidity,...
Passing the baton
January 2026
Probiotics, gut microbiota and physical activity: A close relationship
January 2026
The topic of this review is the study of the gut microbiota (GM), and the use of probiotics, especially in humans, as a new frontier in the field of prevention and health in general. The beneficial...
Impact of wet and dry cupping therapy on endurance, perceived wellness, and exertion in recreational male runners
January 2026
Cupping therapy (CT), an ancient practice revived in modern sports medicine, offers potential benefits for athlete recovery and performance. Distinctions between wet CT (WCT) and dry CT (DCT) in sports...
Resistance exercise alleviates skeletal muscle atrophy through reduction of oxidative stress via Sestrin1 in C57BL/6J mice
January 2026
Resistance exercise has been confirmed to be important for maintaining muscle mass and function. However, despite considerable experimental studies, the underlying mechanisms still requires further...
ATLAS study: Design, athletic performance, and sex-specific regression models for muscle strength in the Greek population
January 2026
ATLAS is a cross-sectional study aiming to investigate environmental and genetic determinants of athletic performance in healthy Greek competitive athletes (CA). This article presents the study design,...
Molecular mechanisms of exercise-induced neuroprotection against Parkinson's disease
January 2026
Parkinson's disease (PD) is the second most common neurodegenerative disease that affects movement and cognitive function, resulting from the loss of the neurotransmitter dopamine due to the death of...
Proprioception deficits in chronic ankle instability associated with structural and functional alternations in cerebellar vermis
January 2026
Ankle proprioception deficits have been widely reported in patients with chronic ankle instability (CAI), but their central neuropathological mechanisms have not been fully discussed. So, we aimed to...
Does longer-muscle length resistance training cause greater longitudinal growth in humans? A systematic review
January 2026
This paper aimed to systematically review the literature regarding the effects of resistance training (RT) performed at longer-muscle length (LML) versus shorter-muscle length (SML) on proxy measurements...
Does transcranial direct current stimulation enhance the hypoalgesic effect of exercise?
January 2026
Exercise produces a decrease in pain sensitivity via an effect called exercise-induced hypoalgesia (EIH). Transcranial direct current stimulation (tDCS), acting on similar analgesic mechanisms as EIH,...
An exerkine-based prognostic index reveals immune heterogeneity and predicts outcomes across 33 cancers
January 2026
Exercise exerts tumor-suppressive effects across multiple malignancies, partly through exerkines—exercise-induced secreted factors with immunomodulatory and metabolic functions. However, the prognostic...