Defecation after magnesium supplementation enhances cognitive performance in triathletes
March 2025
Constipation is correlated with diminished cognitive function, revealing a possible rectum-brain connection. In this counter-balanced crossover trial, 13 elite triathletes underwent a Stroop test to...
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Exercise snacks and physical fitness in sedentary populations
January 2025
Physical inactivity remains a pressing global public health concern. Prolonged periods of sedentary behavior have been linked to heightened risks of non-communicable diseases such as cardiovascular...
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Physical activity, exercise, and chronic diseases: A brief review
December 2019
Chronic diseases are the leading cause of death worldwide with increasing prevalence in all age groups, genders, and ethnicities. Most chronic disease deaths occur in middle-to low-income countries...
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Physical activity, exercise, and mental health of healthy adolescents: A review of the last 5 years
May 2025
The mental health of adolescents is a priority for successful development. Physical activity (PA) and exercise can have effects on the mental health of adolescents. This review analysed the effect that...
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Myocarditis – A silent killer in athletes: Comparative analysis on the evidence before and after COVID-19 pandemic
September 2024
Myocarditis is a rare cardiomyocyte inflammatory process, typically caused by viruses, with potentially devastating cardiac sequalae in both competitive athletes and in the general population. Investigation...
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Current knowledge about pyruvate supplementation: A brief review
December 2024
Pyruvate is a three-carbon ketoacid that occurs naturally in cells. It is produced through enzymatic reactions in the glycolytic pathway and plays a crucial role in energy metabolism. Despite promising...
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Clinical gait analysis in older children with autism spectrum disorder
June 2024
Individuals with autism spectrum disorder (ASD) often exhibit motor deficits that increase their risk of falls. There is a lack of understanding regarding gait biomechanics demonstrated by older children...
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Exercise is mitochondrial medicine for muscle
December 2019
Mitochondria are vital organelles that provide energy for muscle function. When these organelles become dysfunctional, they produce less energy as well as excessive levels of reactive oxygen species...
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Exercise and nutrition benefit skeletal muscle: From influence factor and intervention strategy to molecular mechanism
December 2024
Sarcopenia is a progressive systemic skeletal muscle disease induced by various physiological and pathological factors, including aging, malnutrition, denervation, and cardiovascular diseases, manifesting...
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Going nuclear: Molecular adaptations to exercise mediated by myonuclei
March 2023
Muscle fibers are multinucleated, and muscle fiber nuclei (myonuclei) are believed to be post-mitotic and are typically situated near the periphery of the myofiber. Due to the unique organization of...
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High intensity interval training and molecular adaptive response of skeletal muscle
December 2019
Increased cardiovascular fitness, V˙O2max, is associated with enhanced endurance capacity and a decreased rate of mortality. High intensity interval training (HIIT) is one of the best methods to increase...
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Effects of high-intensity intermittent cross-training on maximal oxygen uptake
May 2025
We investigated the effects of high-intensity intermittent cross-training (HIICT) on maximal oxygen uptake (V˙O2max). The HIICT consisted of alternating intermittent 20-s treadmill running (1st, 3rd,...
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Reasons and promotion strategies of physical activity constraints in obese/overweight children and adolescents
March 2024
To explore the reasons for low levels of physical activity in obese/overweight children and adolescents and to propose appropriate strategies to promote their physical activity (PA). This review followed...
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Combined extracorporeal shockwave therapy and exercise for the treatment of tendinopathy: A narrative review
March 2022
Tendinopathy is a chronic degenerative musculoskeletal disorder that is common in both athletes and the general population. Exercise and extracorporeal shockwave therapy (ESWT) is among the most common...
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Implications of the COVID-19 pandemic on athletes, sports events, and mass gathering events: Review and recommendations
September 2023
Since the coronavirus disease 19 (COVID-19), which caused several respiratory diseases, was formally declared a global pandemic by the World Health Organization (WHO) on March 11, 2020, it affected...
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The effect of incline walking on lower extremity and trunk mechanics in older adults
January 2025
Older adults are at an increased risk of developing knee osteoarthritis. High internal knee abduction moment during daily activities may elevate the risk of knee osteoarthritis. Incline walking exercise...
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An integrative review of the effects of high-intensity interval training on the autonomic nervous system
March 2025
High-Intensity Interval Training (HIIT) has gained prominence as a time-efficient and effective exercise modality to improve cardiovascular (CV) fitness, metabolic health, and physical performance....
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Post-operative protein supplementation following orthopaedic surgery: A systematic review
March 2024
Decreased mechanical loading after orthopaedic surgery predisposes patients to develop muscle atrophy. The purpose of this review was to assess whether the evidence supports oral protein supplementation...
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The COVID-19 pandemic and physical activity
June 2020
The SARS-CoV-2-caused COVID-19 pandemic has resulted in a devastating threat to human society in terms of health, economy, and lifestyle. Although the virus usually first invades and infects the lung...
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High-altitude illnesses: Old stories and new insights into the pathophysiology, treatment and prevention
June 2021
Areas at high-altitude, annually attract millions of tourists, skiers, trekkers, and climbers. If not adequately prepared and not considering certain ascent rules, a considerable proportion of those...
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Inflammation, physical activity, and chronic disease: An evolutionary perspective
March 2020
Low-grade inflammation is emerging as a common feature of contemporary metabolic, psychiatric, and neurodegenerative diseases. Both physical inactivity and abdominal adiposity are associated with persistent...
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Chrono-exercise: Time-of-day-dependent physiological responses to exercise
March 2023
Exercise is an effective strategy to prevent and improve obesity and related metabolic diseases. Exercise increases the metabolic demand in the body. Although many of the metabolic health benefits of...
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Comparison of blood flow restriction training and conventional resistance training for the improvement of sarcopenia in the older adults: A systematic review and meta-analysis
December 2023
Age-related sarcopenia places a tremendous burden on healthcare providers and patients' families. Blood flow restriction (BFR) training may be a promising treatment to bring sarcopenia down, and it...
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Effect of strength training on knee proprioception in patients with knee osteoarthritis: A systematic review and meta-analysis
June 2024
Proprioception is significantly impaired in knee osteoarthritis (KOA), contributing to reduced functionality. Strength training (ST) is essential in KOA by improving muscle strength, although it may...
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2020 WHO guidelines on physical activity and sedentary behavior
June 2021
The World Health Organization released new guidelines on physical activity and sedentary behaviour in November 2020. This commentary summarises these guidelines, including the new elements. An evaluation...
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