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ISSN: 2468-0427
CN: 10-1766/R
p-ISSN: 2468-2152

Quantifying West Nile virus circulation in the avian host population in Northern Italy

West Nile virus (WNV) is one of the most threatening mosquito-borne pathogens in Italy where hundreds of human cases were recorded during the last decade. Here, we estimated the WNV incidence in the...

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Dynamics and asymptotic profiles of a local-nonlocal dispersal SIR epidemic model with spatial heterogeneity

This research investigates a novel approach to modeling an SIR epidemic in a heterogeneous environment by imposing certain restrictions on population mobility. Our study reveals the influence of partially...

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Global infectious disease early warning models: An updated review and lessons from the COVID-19 pandemic

An early warning model for infectious diseases is a crucial tool for timely monitoring, prevention, and control of disease outbreaks. The integration of diverse multi-source data using big data and...

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Can the prevalence of one STI serve as a predictor for another? A mathematical modeling analysis

We aimed to understand to what extent knowledge of the prevalence of one sexually transmitted infection (STI) can predict the prevalence of another STI, with application for men who have sex with men...

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Estimating cumulative infection rate of COVID-19 after adjusting the dynamic zero-COVID policy in China

At the end of 2022, China adjusted its coronavirus disease 2019 (COVID-19) prevention and control strategy. How this adjustment affected the cumulative infection rate is debated, and how second booster...

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Social contact patterns and their impact on the transmission of respiratory pathogens in rural China

Social contact patterns significantly influence the transmission dynamics of respiratory pathogens. Previous surveys have quantified human social contact patterns, yielding heterogeneous results across...

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Treatment failure and the threshold of disease extinction

Antibiotic treatment failure related to carriers poses a serious problem to physicians and epidemiologists. Due to the sparsity of data, assessing the role in infection dynamics is difficult. In this...

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Bayesian spatio-temporal modeling of severe acute respiratory syndrome in Brazil: A comparative analysis across pre-, during, and post-COVID-19 eras

This paper presents an investigation into the spatio-temporal dynamics of Severe Acute Respiratory Syndrome (SARS) across the diverse health regions of Brazil from 2016 to 2024. Leveraging extensive...

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A modelling approach to characterise the interaction between behavioral response and epidemics: A study based on COVID-19

During epidemic outbreaks, human behavior is highly influential on the disease transmission and hence affects the course, duration and outcome of the epidemics. In order to examine the feedback effect...

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Forecasting influenza epidemics in China using transmission dynamic model with absolute humidity

An influenza forecasting system is critical to influenza epidemic preparedness. Low temperature has long been recognized as a condition favoring influenza epidemic, yet it fails to justify the summer...

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Regional variations in HIV diagnosis in Japan before and during the COVID-19 pandemic

The number of people undergoing voluntary HIV testing has abruptly decreased since 2020. The geographical heterogeneity of HIV infection and the impact of COVID-19 on the diagnosis of HIV at regional...

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A data science pipeline applied to Australia's 2022 COVID-19 Omicron waves

The field of software engineering is advancing at astonishing speed, with packages now available to support many stages of data science pipelines. These packages can support infectious disease modelling...

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Exploring the influencing factors of scrub typhus in Gannan region, China, based on spatial regression modelling and geographical detector

Scrub typhus is a significant public health issue with a wide distribution and is influenced by various determinants. However, in order to effectively eradicate scrub typhus, it is crucial to identify...

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Assessing the impact of disease incidence and immunization on the resilience of complex networks during epidemics

Disease severity through an immunized population ensconced on a physical network topology is a key technique for preventing epidemic spreading. Its influence can be quantified by adjusting the common...

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Flexible regression model for predicting the dissemination of Candidatus Liberibacter asiaticus under variable climatic conditions

Greening, or Huanglongbing (HLB), poses a severe threat to global citrus cultivation, affecting various citrus species and compromising fruit production. Primarily transmitted by psyllids during phloem...

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A heterogeneous continuous age-structured model of mumps with vaccine

In classical mumps models, individuals are generally assumed to be uniformly mixed (homogeneous), ignoring population heterogeneity (preference, activity, etc.). Age is the key to catching mixed patterns...

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Nonlinear mixed models and related approaches in infectious disease modeling: A systematic and critical review

The level of surveillance and preparedness against epidemics varies across countries, resulting in different responses to outbreaks. When conducting an in-depth analysis of microinfection dynamics,...

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Impact of vaccination on Omicron's escape variants: Insights from fine-scale modelling of waning immunity in Hong Kong

COVID-19 vaccine-induced protection declines over time. This waning of immunity has been described in modelling as a lower level of protection. This study incorporated fine-scale vaccine waning into...

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Predicting influenza in China from October 1, 2023, to February 5, 2024: A transmission dynamics model based on population migration

Since November 2023, influenza has ranked first in reported cases of infectious diseases in China, with the outbreak in both northern and southern provinces exceeding the levels observed during the...

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Planning and adjusting the COVID-19 booster vaccination campaign to reduce disease burden

As public health policies shifted in 2023 from emergency response to long-term COVID-19 disease management, immunization programs started to face the challenge of formulating routine booster campaigns...

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Gradient boosting: A computationally efficient alternative to Markov chain Monte Carlo sampling for fitting large Bayesian spatio-temporal binomial regression models

Disease forecasting and surveillance often involve fitting models to a tremendous volume of historical testing data collected over space and time. Bayesian spatio-temporal regression models fit with...

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A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study

The outbreak of respiratory diseases, such as COVID-19 and influenza, has drawn global attention. However, it remains unclear whether the risk of influenza A infection may be affected by the history...

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Modelling and investigating memory immune responses in infectious disease. Application to influenza a virus and sars-cov-2 reinfections

Understanding effector and memory immune responses against influenza A virus (IAV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and re-infections is extremely important,...

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Dynamics of an SVEIR transmission model with protection awareness and two strains

As of May 2024, the main strains of COVID-19 caused hundreds of millions of infection cases and millions of deaths worldwide. In this study, we consider the COVID-19 epidemics with the main strains...

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Stronger binding affinities of gp120/CD4 in Catarrhini provide insights into HIV/host interactions

Human immunodeficiency virus-1 (HIV-1) exploits the viral gp120 protein and host CD4/CCR5 receptors for the pandemic infection to humans. The host co-receptors of not only humans but also several primates...

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