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ISSN: 2949-9240

World malaria report 2025: Growing biological threats, shrinking resources

The World Malaria Report 2025 documents operational progress while exposing systemic vulnerabilities that could reverse two decades of gains. Several biological threats are converging in Sub-Saharan...

Artificial intelligence and big data for decoding infectious disease transmission dynamics and outbreak prediction

Understanding and predicting infectious disease transmission remains a central challenge in global health due to the complex interplay of pathogen evolution, host biology, environmental conditions,...

Mosquitoes as pesticide disseminators: Advancing pyriproxyfen-based technologies for next-generation vector control

Mosquito-borne diseases, including dengue, Zika, chikungunya, and malaria, pose significant global health challenges, exacerbated by rising insecticide resistance in key vectors like Aedes and Anopheles....

Recurring diphtheria outbreaks in Nigeria: A holistic review of challenges, knowledge and strategic recommendations for control

Diphtheria is a vaccine-preventable bacterial disease that has contributed to the large number of deaths in Nigeria. There have been numerous outbreaks after the COVID-19 pandemic. However, the challenges...

WHO report signals tuberculosis resurgence: Addressing systemic failures and revamping control strategies

According to the World Health Organization's Global Tuberculosis Report 2024, tuberculosis (TB) has resurged as the leading cause of death from a single infectious agent, overtaking Coronavirus disease...

Revolutionizing infectious disease surveillance: Multi-omics technologies and AI-driven integration

The integration of advanced technologies, including next-generation sequencing, multiomics approaches, and artificial intelligence (AI), has revolutionized pathogen surveillance and preparedness. Multiomics...

Recurrent cholera outbreaks in Nigeria: A review of the underlying factors and redress

Cholera outbreaks remain a matter of public health since this outbreak of the epidemic is experienced almost every year. In June 2024, the African Region had registered 7964 new cases of cholera across...

Decoding the Bite: Sensory cues, host heterogeneity, and pathogen manipulation in mosquito host-seeking behavior

Mosquitoes, primarily females, require blood meals for reproduction, making them prolific biters and major vectors of diseases such as malaria, dengue, Zika, and West Nile. This review synthesizes the...

Decoding the host-pathogen-environment interaction: Integrated insights into Helicobacter pylori virulence and epidemiological transmission

A primary cause of peptic ulcer, gastric carcinoma, and chronic gastritis is the Gram-negative pathogenic bacteria Helicobacter pylori (H. pylori). Grasping its mechanisms of pathogenesis and transmission...

NMCR-6, a novel nonmobile colistin resistance gene in Vibrio bacteria: full characterization and global perspective

Amid rising bacterial resistance, polymyxins are a critical last resort against multidrug-resistant Gram-negative infections. Understanding and predicting the emergence of novel, nonmobile colistin...

Global, regional, and national burden of malaria, 1990–2021: Findings from the global burden of disease study 2021

Malaria is an infectious disease transmitted by mosquitoes and caused by Plasmodium parasites. This study analyzes data from the Global Burden of Disease (GBD) Study 2021 to systematically assess global...

Global, regional, and national burden of dengue, 1990–2021: Findings from the global burden of disease study 2021

Dengue is an acute viral infectious disease caused by the dengue virus and transmitted through mosquitoes. Although numerous studies have examined the global burden of dengue, comprehensive and systematic...

An integrated review of ecology, epidemiology, and public health burden of anthrax in Africa

The emergence and re-emergence of anthrax across Africa remain a persistent public health and veterinary concern. In recent years, several African countries have experienced recurrent outbreaks, underscoring...

Rabies in Africa: Vaccination coverage and strategies for elimination by 2030

Rabies remains a significant public health threat in Africa, and disproportionately impacts vulnerable populations to cause thousands of deaths annually. Rabies is a preventable disease and control...

Emergencies of zoonotic diseases, drivers, and the role of artificial intelligence in tracking the epidemic and pandemics

Zoonotic illnesses are defined as diseases that can be transmitted from animals to humans through various channels. More than sixty percent of disease-causing organisms capable of affecting humans are...

Breaking barriers for key populations in the lenacapavir era

Despite advances in human immunodeficiency virus (HIV) prevention, key populations including men who have sex with men (MSM), sex workers, transgender individuals, people who inject drugs, and adolescent...

The Alongshan virus: A comprehensive review of its pathogenic characteristics, epidemiology, and detection strategies

Alongshan virus (ALSV) is an emerging tick-borne segmented RNA virus belonging to the Flaviviridae family, first identified in Northeastern China in 2017. ALSV is currently classified within the Jingmenvirus...

The impact of environmental and host factors on wolbachia density and efficacy as a biological tool

Wolbachia, a bacterium found naturally in some species of Aedes and Culex mosquitoes, has gained significant attention for it's potential in controlling mosquito-borne diseases and suppressing mosquito...

Machine learning models for predicting residual malaria infections using environmental factors: A case study of the Jazan region, Kingdom of Saudi Arabia

Malaria is a global public health problem affecting more than 100 countries. Meteorological factors on the other hand represent a major driving force behind malaria transmission and other vector-borne...

Mosquito immunity and its defense against malaria parasite

Mosquito immunity serves as a critical factor limiting the development of Plasmodium parasites within mosquitoes. Unlike vertebrate, mosquitoes rely solely on innate immune responses, which nonetheless...

Influences of vaginal microbiota on human papillomavirus infection and host immune regulation: What we have learned?

The alteration of microbiota in different host niches has been associated with numerous adverse health outcomes that affect millions of human patients annually. In last few years the interest has been...

Maternal immune activation and neuropsychiatric disease in offspring: Pathogen's perspective

Neuropsychiatric disorders (NDDs) have been associated with maternal immune activation (MIA) in epidemiologic studies, such as prospective birth cohort studies. There is evidence linking maternal infectious...

Trend, pattern, and outcome of meningitis cases in Northwest, Nigeria: A 10 Year review of case-based surveillance data

This study aimed to describe the epidemiological pattern of Cerebrospinal meningititis (CSM) cases, and related mortality in Jigawa State, Northwest Nigeria, over a 10-year period....

Advances and challenges in the prevention, control and research of echinococcosis in China

Echinococcosis is a group of chronic zoonotic parasitic diseases caused by the larval stage of Echinococcus tapeworms, which infect both humans and animals. Due to the complex life cycle, broad geographic...

mRNA vaccination facilitates the prevention and control of infectious diseases at an unprecedented speed

In recent years, amidst the progresses of biotechnology versus the emergence and evolution of diseases, the pursuit of mRNA (messenger RNA) vaccines has become a focal point, particularly after their...

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