Recurrent cholera outbreaks in Nigeria: A review of the underlying factors and redress
2025
Cholera outbreaks remain a matter of public health since this outbreak of the epidemic is experienced almost every year. In June 2024, the African Region had registered 7964 new cases of cholera across...
Emergencies of zoonotic diseases, drivers, and the role of artificial intelligence in tracking the epidemic and pandemics
2024
Zoonotic illnesses are defined as diseases that can be transmitted from animals to humans through various channels. More than sixty percent of disease-causing organisms capable of affecting humans are...
Global, regional, and national burden of dengue, 1990–2021: Findings from the global burden of disease study 2021
2024
Dengue is an acute viral infectious disease caused by the dengue virus and transmitted through mosquitoes. Although numerous studies have examined the global burden of dengue, comprehensive and systematic...
WHO report signals tuberculosis resurgence: Addressing systemic failures and revamping control strategies
2025
According to the World Health Organization's Global Tuberculosis Report 2024, tuberculosis (TB) has resurged as the leading cause of death from a single infectious agent, overtaking Coronavirus disease...
Global, regional, and national burden of malaria, 1990–2021: Findings from the global burden of disease study 2021
2024
Malaria is an infectious disease transmitted by mosquitoes and caused by Plasmodium parasites. This study analyzes data from the Global Burden of Disease (GBD) Study 2021 to systematically assess global...
Response to Chikungunya fever in China: are we ready?
2025
Chikungunya fever (CHIK) is caused by the Chikungunya virus (CHIKV), a mosquito-borne RNA virus of the Alphavirus genus (family Togaviridae). CHIK has been imported and caused several local epidemic...
Recurring diphtheria outbreaks in Nigeria: A holistic review of challenges, knowledge and strategic recommendations for control
2025
Diphtheria is a vaccine-preventable bacterial disease that has contributed to the large number of deaths in Nigeria. There have been numerous outbreaks after the COVID-19 pandemic. However, the challenges...
A review of epidemiological characteristics, risk factors, and prevention strategies of human anthrax in China
2024
Anthrax is a severe infectious illness triggered by the bacterium Bacillus anthracis. This bacterium is naturally found in soil and mainly impacts domestic and wild animals. Human anthrax infection...
Rabies in Africa: Vaccination coverage and strategies for elimination by 2030
2025
Rabies remains a significant public health threat in Africa, and disproportionately impacts vulnerable populations to cause thousands of deaths annually. Rabies is a preventable disease and control...
The prevalence, diagnosis, and dissemination of mcr-1 in colistin resistance: Progress and challenge
2023
Considered as the last defense line against Gram-negative bacteria, colistin is particularly effective against multiple drug-resistant bacteria such as multi-drug resistance (MDR) and carbapenem-resistant...
Influences of vaginal microbiota on human papillomavirus infection and host immune regulation: What we have learned?
2023
The alteration of microbiota in different host niches has been associated with numerous adverse health outcomes that affect millions of human patients annually. In last few years the interest has been...
Efforts of rabies elimination with a One Health approach and SARE tools in Ethiopia
2024
Rabies is a viral zoonosis which affects nearly every region of the world. Once symptoms appear, the disease is 100 % fatal, although it is 100 % preventable through vaccination. Human rabies is typically...
Decoding the Bite: Sensory cues, host heterogeneity, and pathogen manipulation in mosquito host-seeking behavior
2025
Mosquitoes, primarily females, require blood meals for reproduction, making them prolific biters and major vectors of diseases such as malaria, dengue, Zika, and West Nile. This review synthesizes the...
Maternal immune activation and neuropsychiatric disease in offspring: Pathogen's perspective
2024
Neuropsychiatric disorders (NDDs) have been associated with maternal immune activation (MIA) in epidemiologic studies, such as prospective birth cohort studies. There is evidence linking maternal infectious...
Circadian rhythm of mosquitoes: Blood feeding and disease transmission
2025
The circadian rhythm refers to the adjustment of behavioural rhythms of organisms' to the environmental cues. The rhythm adjusting and maintaining is done through an internal timekeeping mechanism....
The impact of environmental and host factors on wolbachia density and efficacy as a biological tool
2023
Wolbachia, a bacterium found naturally in some species of Aedes and Culex mosquitoes, has gained significant attention for it's potential in controlling mosquito-borne diseases and suppressing mosquito...
Machine learning models for predicting residual malaria infections using environmental factors: A case study of the Jazan region, Kingdom of Saudi Arabia
2024
Malaria is a global public health problem affecting more than 100 countries. Meteorological factors on the other hand represent a major driving force behind malaria transmission and other vector-borne...
A novel approach to disease modeling: The SEIVR model with a vulnerable compartment
2025
The SEIR model is a cornerstone in epidemiology and offers insights into the spread of infectious diseases. It extends the basic SIR model to include an Exposed (E) compartment, to account for the incubation...
The Alongshan virus: A comprehensive review of its pathogenic characteristics, epidemiology, and detection strategies
2025
Alongshan virus (ALSV) is an emerging tick-borne segmented RNA virus belonging to the Flaviviridae family, first identified in Northeastern China in 2017. ALSV is currently classified within the Jingmenvirus...
Advances and challenges in the prevention, control and research of echinococcosis in China
2025
Echinococcosis is a group of chronic zoonotic parasitic diseases caused by the larval stage of Echinococcus tapeworms, which infect both humans and animals. Due to the complex life cycle, broad geographic...
Genomic insights into disease vectors: Divergent evolution of mosquitoes, tsetse flies, sand flies and kissing bugs
2025
Vector-borne diseases pose major global health challenges, with mosquitoes, tsetse flies, and sand flies serving as key insect vectors. This review explores the genomic basis of hematophagy, reproduction,...
mRNA vaccination facilitates the prevention and control of infectious diseases at an unprecedented speed
2025
In recent years, amidst the progresses of biotechnology versus the emergence and evolution of diseases, the pursuit of mRNA (messenger RNA) vaccines has become a focal point, particularly after their...
Genome-wide identification of characteristic nucleotide fragments for surveillance and subtype typing of influenza A viruses
2025
Influenza A viruses, members of the Orthomyxoviridae family, are major causative agents of past flu pandemics and can infect a wide range of hosts depending on their hemagglutinin (HA) and neuraminidase...
Trends in the minimum inhibitory concentrations for four agents against methicillin-resistant Staphylococcus aureus in bloodstream infections in China: a 6-year multi-center study from 2017 to 2022
2025
Staphylococcus aureus bacteremia is a critical and pernicious infection, and in particular methicillin-resistant Staphylococcus aureus (MRSA) is increasing in treatment failure. This study analyzed...
S–6P exhibits better immunogenicity than S–2P at lower doses of COVID-19 mRNA vaccines
2024
The objective of this study was to determine whether a new combination of immunogens could be more effective than the S–2P design in terms of eliciting an immune response. The study aimed to use a unified...