Lab-on-a-chip technologies: The future of precision medicine and high-throughput biomolecular analysis
December 2025
Over the past few decades, advancements in microfabrication and biomaterials have driven the innovation of microfluidic technologies, significantly advancing the development of lab-on-a-chip (LOC) systems....
Healthcare monitoring with earables: A paradigm shift towards digital health
December 2025
The convergence of consumer electronics and digital health has spurred the rise of earables—advanced in-ear wearable devices that exploit their unique anatomical position to monitor a wide range of...
Preparation and evaluation of iRGD-modified PLGA-PEG nanoparticles encapsulating TPEN
June 2026
This study developed an iRGD-modified PLGA-PEG nanoparticle for targeted delivery of the metal chelator N,N,N′,N′-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). Different from conventional nanoplatforms...
Direct mass spectrometry for traditional Chinese medicine analysis: Analytical strategies, applications, and future perspectives
June 2026
Direct mass spectrometry has become an important analytical approach in traditional Chinese medicine (TCM) because it enables rapid, direct, and minimally destructive characterization with little or...
A review of extraction, synthesis, and pharmacological activities of naringenin and its derivatives
September 2025
Naringenin, a polyphenolic flavanone, exhibits diverse pharmacological and biological activities, including anti-inflammatory, antioxidant, anti-obesity, anticancer, antidiabetic, and antimicrobial...
Industry 4.0 and circular economy for bolstering healthcare sector: A comprehensive view on challenges, implementation, and futuristic aspects
June 2024
Industry 4.0 technologies are also strengthening the circular economy and circular healthcare. It is accomplished by implementing methods to reduce waste and undertake advanced sustainability initiatives....
Molecular docking, molecular dynamics simulation and MM-PB/GBSA analysis for the inhibition of Klebsiella pneumoniae SHV-1 β-lactamase using antimicrobial peptides defensin VvK1 and snakin-1
June 2025
This computational study aims to explore the inhibition property of two plant-derived AMPs (antimicrobial peptides), defensin VvK1 and snakin-1, against SHV-1 β-lactamase from Klebsiella pneumoniae...
Machine learning driven multi omics and probiotic integration for precision colorectal cancer management
June 2026
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, driven by tumor heterogeneity, late-stage detection, and variable therapeutic response. The integration of machine...
Multi-omics analysis reveals synergistic interplay of metabolic dysregulation, oxidative stress, and inflammation in polycystic ovary syndrome
June 2025
Polycystic ovary syndrome (PCOS) is a multifactorial endocrine and metabolic disorder characterized by hormonal imbalances, metabolic dysfunction, and chronic inflammation. To elucidate the molecular...
Graphene-enabled glucose biosensors: Toward flexible, non-invasive, and wearable technologies
December 2025
The global diabetes epidemic necessitates precise, affordable, and continuous glucose monitoring technologies. Graphene and its derivatives, with their high conductivity, tunable chemistry, and mechanical...
Hanning FIR window filtering analysis for EEG signals
June 2024
The window function is a mathematical function in signal processing that is multiplied by a signal to lessen or eliminate the impact of undesired characteristics such as spectral leakage and edge effects...
Progress in non-endocytic dependent transmembrane delivery of biological macromolecules
June 2026
Biomacromolecules—including proteins, nucleic acids, and gene-editing tools—have demonstrated immense potential for therapeutic applications. However, their intracellular bioavailability is severely...
Preparation and characterization of phenylboronic acid cross-linked hydrogel
March 2026
Hydrogels demonstrate significant value in the biomedical field, particularly in wound management and tissue engineering, owing to their unique three-dimensional network structure, excellent biocompatibility,...
Radio conjugated nanoparticles for cancer theranostics: Advances in targeted imaging and radiotherapy
December 2025
Cancer remains one of the most challenging diseases worldwide due to limitations in conventional diagnostic and therapeutic approaches, including non-specific targeting, multidrug resistance, and systemic...
pH-responsive antibacterial biomedical platform based on SH@ZIF-8/AgNPs promotes healing of infected wounds
March 2026
Infected wounds feature an acidic microenvironment, providing an endogenous stimulus for targeted therapy. Taking advantage of the acid-triggered decomposition of zeolitic imidazolate framework-8 (ZIF-8),...
An ensemble machine learning-based approach to predict thyroid disease using hybrid feature selection
September 2024
Thyroid issues are becoming more and more common, and early detection is critical for therapy that reduces mortality and complications. Because of these factors, detecting thyroid problems has become...
Aptamer-carbon quantum dots and silver nanoparticles construct a FRET sensor for sensitive detection of E. coli
June 2024
E. coli is considered to be one of the most dangerous foodborne pathogens and precise detection of E. coli in food is required to ensure the quality and safety of food. In this work, carbon quantum...
Development of nanogold immunochromatographic assay strip based on novel nanobody for rapid detection of imazalil in food and environmental water samples
March 2026
The misuse of the broad-spectrum fungicide imazalil (IMZ) poses significant challenges to food safety and environmental safety, which requires rapid and accurate methods for detecting IMZ in complex...
Recent progress in the rational design and applications of nanozymes
March 2025
In order to overcome the limitations of natural enzymes, nanomaterials with enzyme-like activity, commonly named as nanozymes, have been widely studied in the past few decades. Due to their distinctive...
Advances in fluorescence imaging of RNAs in living cells based on functional nucleic acid probes
March 2024
RNA is an essential biomolecule that determines and regulates numerous biological process in cells. The sensitive and specific imaging of the expression level, localization and dynamic change of RNAs...
Ameliorative effects of silver nanoparticles on hyperglycemia-induced cellular stress in gangrene
June 2026
Diabetes-induced hyperglycemia leads to oxidative stress, inflammation, and impaired wound healing, particularly in gangrene. In this study, silver nanoparticles (AgNPs) were synthesized using flower...
Optical pickup unit-based fluorescence microscope with autofocus and deep learning capabilities
September 2024
An autofocus, cost-effective fluorescence microscope instrument is made using a commercially available Blu-ray disc optical pickup head (OPU). This ABFM consists of the optical path, system control...
Wearable Janus nanofiber membrane-based colorimetric sensors for directional transfer and analysis of sweat
March 2024
Wearable sweat sensors are promising for real-time personalized health monitoring in a noninvasive manner. However, how to improve the wearing comfort and accuracy affected by sweat accumulation and...
Establishment of a triplex real-time quantitative fluorescence PCR method for detecting drug resistance genes mcr-1, blaNDM-1, and vanA
March 2025
This study establishes a triplex real-time quantitative fluorescence polymerase chain reaction (PCR) method for simultaneous and rapid MCR-1, vanA, and blaNDM-1 detection. Different primer-probe combinations...
A dual-mode paper-based microfluidic chip for protamine detection
December 2025
Timely and accessible fertility screening remains a challenge for male reproductive health, where privacy and convenience are often critical. Here, we present a dual-mode paper-based microfluidic device...