Lab-on-a-chip technologies: The future of precision medicine and high-throughput biomolecular analysis
December 2025
Over the past few decades, advancements in microfabrication and biomaterials have driven the innovation of microfluidic technologies, significantly advancing the development of lab-on-a-chip (LOC) systems....
Healthcare monitoring with earables: A paradigm shift towards digital health
December 2025
The convergence of consumer electronics and digital health has spurred the rise of earables—advanced in-ear wearable devices that exploit their unique anatomical position to monitor a wide range of...
Machine learning driven multi omics and probiotic integration for precision colorectal cancer management
June 2026
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, driven by tumor heterogeneity, late-stage detection, and variable therapeutic response. The integration of machine...
A review of extraction, synthesis, and pharmacological activities of naringenin and its derivatives
September 2025
Naringenin, a polyphenolic flavanone, exhibits diverse pharmacological and biological activities, including anti-inflammatory, antioxidant, anti-obesity, anticancer, antidiabetic, and antimicrobial...
Multi-omics analysis reveals synergistic interplay of metabolic dysregulation, oxidative stress, and inflammation in polycystic ovary syndrome
June 2025
Polycystic ovary syndrome (PCOS) is a multifactorial endocrine and metabolic disorder characterized by hormonal imbalances, metabolic dysfunction, and chronic inflammation. To elucidate the molecular...
Direct mass spectrometry for traditional Chinese medicine analysis: Analytical strategies, applications, and future perspectives
June 2026
Direct mass spectrometry has become an important analytical approach in traditional Chinese medicine (TCM) because it enables rapid, direct, and minimally destructive characterization with little or...
Preparation and evaluation of iRGD-modified PLGA-PEG nanoparticles encapsulating TPEN
June 2026
This study developed an iRGD-modified PLGA-PEG nanoparticle for targeted delivery of the metal chelator N,N,N′,N′-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). Different from conventional nanoplatforms...
Progress in non-endocytic dependent transmembrane delivery of biological macromolecules
June 2026
Biomacromolecules—including proteins, nucleic acids, and gene-editing tools—have demonstrated immense potential for therapeutic applications. However, their intracellular bioavailability is severely...
Molecular docking, molecular dynamics simulation and MM-PB/GBSA analysis for the inhibition of Klebsiella pneumoniae SHV-1 β-lactamase using antimicrobial peptides defensin VvK1 and snakin-1
June 2025
This computational study aims to explore the inhibition property of two plant-derived AMPs (antimicrobial peptides), defensin VvK1 and snakin-1, against SHV-1 β-lactamase from Klebsiella pneumoniae...
Industry 4.0 and circular economy for bolstering healthcare sector: A comprehensive view on challenges, implementation, and futuristic aspects
June 2024
Industry 4.0 technologies are also strengthening the circular economy and circular healthcare. It is accomplished by implementing methods to reduce waste and undertake advanced sustainability initiatives....
Microfluidic flow cytometry toward point-of-care testing: advances in fluid driving, cell focusing, signal detection, and data analysis
September 2026
Microfluidic technologies, with advantages in low sample consumption, controllable fluid manipulation, structural integration, and system miniaturization, provide a promising route for adapting flow...
Radio conjugated nanoparticles for cancer theranostics: Advances in targeted imaging and radiotherapy
December 2025
Cancer remains one of the most challenging diseases worldwide due to limitations in conventional diagnostic and therapeutic approaches, including non-specific targeting, multidrug resistance, and systemic...
Hanning FIR window filtering analysis for EEG signals
June 2024
The window function is a mathematical function in signal processing that is multiplied by a signal to lessen or eliminate the impact of undesired characteristics such as spectral leakage and edge effects...
Preparation and evaluation of bovine serum albumin-protected copper sulfide nanoparticles
September 2026
This study aimed to prepare bovine serum albumin (BSA)-protected copper sulfide nanoparticles (CuS@BSA), systematically characterize their physicochemical properties, and preliminarily evaluate their...
Development of a certified reference material for Angiotensin Ⅱ with the mass balance method and isotope dilution mass spectrometry method
September 2026
Angiotensin Ⅱ, the primary effector of the renin-angiotensin-aldosterone system, plays a significant role in blood pressure regulation and fluid-electrolyte homeostasis. It also serves as a crucial...
Graphene-enabled glucose biosensors: Toward flexible, non-invasive, and wearable technologies
December 2025
The global diabetes epidemic necessitates precise, affordable, and continuous glucose monitoring technologies. Graphene and its derivatives, with their high conductivity, tunable chemistry, and mechanical...
Wearable Janus nanofiber membrane-based colorimetric sensors for directional transfer and analysis of sweat
March 2024
Wearable sweat sensors are promising for real-time personalized health monitoring in a noninvasive manner. However, how to improve the wearing comfort and accuracy affected by sweat accumulation and...
A comprehensive study on epigenetic biomarkers in early detection and prognosis of Alzheimer's disease
June 2024
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by beta-amyloid plaques and tau tangles, disrupting brain cell communication, causing atrophy, and leading to cognitive decline....
Preparation and characterization of phenylboronic acid cross-linked hydrogel
March 2026
Hydrogels demonstrate significant value in the biomedical field, particularly in wound management and tissue engineering, owing to their unique three-dimensional network structure, excellent biocompatibility,...
Label-free enrichment and identification of circulating tumor cells integrating inertial microfluidics and deep learning
September 2026
Circulating tumor cells (CTCs) hold great promise as liquid biopsy biomarkers for cancer diagnosis and treatment monitoring. However, their efficient enrichment and accurate identification from blood...
Ameliorative effects of silver nanoparticles on hyperglycemia-induced cellular stress in gangrene
June 2026
Diabetes-induced hyperglycemia leads to oxidative stress, inflammation, and impaired wound healing, particularly in gangrene. In this study, silver nanoparticles (AgNPs) were synthesized using flower...
The dawn of spatiotemporal transcriptomics
June 2024
Gene expression of cells in the tissues is a heterogeneous and dynamic program across space and time. Spatiotemporal transcriptomics technologies have emerged as transforming tools to dissect the spatiotemporal...
Development of nanogold immunochromatographic assay strip based on novel nanobody for rapid detection of imazalil in food and environmental water samples
March 2026
The misuse of the broad-spectrum fungicide imazalil (IMZ) poses significant challenges to food safety and environmental safety, which requires rapid and accurate methods for detecting IMZ in complex...
pH-responsive antibacterial biomedical platform based on SH@ZIF-8/AgNPs promotes healing of infected wounds
March 2026
Infected wounds feature an acidic microenvironment, providing an endogenous stimulus for targeted therapy. Taking advantage of the acid-triggered decomposition of zeolitic imidazolate framework-8 (ZIF-8),...
Aptamer-carbon quantum dots and silver nanoparticles construct a FRET sensor for sensitive detection of E. coli
June 2024
E. coli is considered to be one of the most dangerous foodborne pathogens and precise detection of E. coli in food is required to ensure the quality and safety of food. In this work, carbon quantum...