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ISSN: 2950-2489

Zoonotic diseases (zoonoses): Definitions, classifications, hazards, and prevention strategies

Zoonotic diseases, also known as zoonoses, are infectious diseases that can be transmitted between humans and animals, including livestock, wildlife, and companion animals. These diseases have become...

Mechanisms of transmission and pathogenesis of alphaviruses

Alphavirus is a genus of single-stranded positive sense RNA viruses, which infect vertebrate animals (humans, horses, rodents etc.) and/or arthropods. Medically important alphaviruses are mainly transmitted...

Negative energy balance in transition dairy cows: Mechanisms, systemic impacts, and integrated prevention strategies

Negative energy balance (NEB) is the central metabolic challenge of transition dairy cows and a major driver of impaired health, productivity, and reproductive performance during the periparturient...

A comprehensive review of tick-borne disease epidemiology, clinical manifestations, pathogenesis, and prevention

Ticks are arthropod vectors that transmit pathogens by biting and bloodsucking, and they have been found to carry or transmit over one hundred types of pathogens. The majority of these pathogens are...

Virulence factors in biofilm formation and therapeutic strategies for Staphylococcus aureus: A review

Staphylococcus aureus (S. aureus) is a significant human pathogen known for its ability to form biofilms, which increase its resistance to antibiotics and immune defenses. This review delves into the...

Persistent and recurrent Staphylococcus aureus infection: Biofilms, antibiotic tolerance, protected lesion niches, and therapeutic strategies

Staphylococcus aureus (S. aureus) causes acute invasive disease as well as persistent and recurrent infections involving skin and soft tissue, the bloodstream and endovascular structures, bone and joints,...

Experimental animal models for urolithiasis (kidney stone): A comprehensive review

Experimental animal models play a crucial role in scientific research in different fields such as medicine, biology and pharmacology. Animal models help to understanding human physiology and pathology...

Environmental and mosquito microbiomes affect mosquito-borne disease transmission under climate change

Mosquito-borne diseases remain a major global health challenge, and their transmission dynamics are increasingly influenced by climate change. Rising temperatures, altered precipitation, and extreme...

A multidimensional analysis of the pathogenesis of endometritis in dairy cows: A review

Bovine endometritis is a major reproductive disease in postpartum dairy cows that significantly undermines herd productivity and the long-term economic sustainability of dairy operations globally. This...

The cellular host factors for severe fever with thrombocytopenia syndrome virus infection

Severe fever with thrombocytopenia syndrome (SFTS) is a newly discovered life-threatening disease caused by SFTS virus (SFTSV), an emerging tick-borne bunyavirus. The severity of SFTSV infection can...

Recent progress on rapid diagnostic methods for viral diseases

Viral diseases pose a persistent and evolving threat to global public health, with far-reaching impacts on clinical practice, epidemiology, and socioeconomic stability. Over the past decade, frequent...

Emerging zoonotic and One Health-relevant pathogens in water systems: Surveillance and detection approaches

Wastewater-based epidemiology (WBE) and environmental surveillance have become important components of One Health strategies to monitor zoonotic and environmentally transmitted pathogens. Improvements...

Zoonotic diseases in low and middle-income countries (LMICs): Economic burden, challenges, strategies, and future directions

More than 200 zoonotic diseases are known to affect humans, representing a significant share of both emerging and existing infectious diseases worldwide. These diseases pose a major global public health...

Centennial African swine fever: A comprehensive overview

African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and often fatal disease that affects domestic pigs and wild boars. Since its initial identification in Kenya...

Epidemiology, antimicrobial resistance, economic burden and management approaches for Staphylococcus aureus-associated bovine mastitis: A systematic review

Bovine mastitis, an inflammatory condition of the mammary gland, represents a formidable challenge to the global dairy industry, causing substantial economic losses and posing significant public health...

Organoids of the reproductive system: A comprehensive review of advances in male and female models, disease applications, and future perspectives

Organoid technology has emerged as an important platform for reproductive system research. Compared with traditional two-dimensional culture systems, organoids are three-dimensional in vitro models...

Advances in endometrial receptivity and embryo implantation by multi-omics techniques

Endometrial receptivity is a critical determinant of successful embryo implantation, yet current clinical assessments (e.g., ultrasound, hysteroscopy) primarily focus on morphological evaluation and...

Flagellin: A crucial virulence factor coordinating bacterial pathogenesis and host immune responses

Flagella serve as the motility organs of bacteria, possessing not only the capability to facilitate movement through mechanisms such as rotation and swinging but also playing a crucial role in the establishment...

Advances in antiviral agents: A concise review

Emerging and re-emerging viral infections continue to pose serious threats to global health, agriculture, and ecosystems. The rise of drug-resistant strains highlights the pressing demand for innovative...

Host immune response to Cryptosporidium spp.: Insights and perspectives for vaccine development

Cryptosporidium, a zoonotic protozoan parasite, poses a significant threat to both public health and the livestock sectors globally, leading to lethal diarrheal disease and associated economic losses....

Pathogens infected or carried by exotic pets pose emerging threat to human health

Exotic pets refer to a variety of uncommon pets that are different from traditional pets such as cats, dogs, birds and fish. Due to the convenience of international travel, the diversity and globalization...

Multidimensional pathogenic mechanisms of bovine viral diarrhea virus: From cell invasion to immune evasion

Bovine viral diarrhea virus (BVDV) is a significant economic pathogen capable of establishing persistent infections in cattle, posing a major challenge to global cattle industries. This review systematically...

Rheumatoid arthritis animal model in mice

Rheumatoid arthritis (RA) is an autoimmune disease that causes significant disability and has a high recurrence rate. Currently, there is no cure for this disease. Identifying the cause of RA and developing...

Toxic effects and detoxification strategies of aflatoxin B1

Aflatoxin B1 (AFB1), a highly carcinogenic mycotoxin produced primarily by Aspergillus flavus and A. parasiticus, is classified as a Group 1 carcinogen by the International Agency for Research on Cancer...

Prevalence of zoonotic diseases in the Northeastern region, one health perspective

Zoonotic diseases are long known for their disease transmission from animals to human beings or from human beings to animals. These illnesses are primarily spread by the ingestion of contaminated food...

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