Machine learning and IoT in healthcare: Recent advancements, challenges & future direction
2025
The integration of Machine Learning and Deep Learning with IoT-enabled devices for real-time health monitoring has significantly revolutionized healthcare. These technologies facilitate the analysis...
Therapeutic potential of black seed oil in treating rheumatoid arthritis: Insights on biochemical and genetic analyses of inflammatory signaling transducer
2024
Nigella sativa (Black seed) has been a longstanding component of traditional medicine. Rheumatoid arthritis, an autoimmune disorder targeting bone, cartilage, and synovial cells, leads to enduring joint...
A brief history of urine examination - From ancient uroscopy to 21st century urinomics
2024
The art of uroscopy (Greek ouron-urine and skopeo-examination), the visual inspection of urine, is as old as the history of mankind. It had seen its ups and downs, was praised and derided, but was ultimately...
Decoding inflammatory signaling networks: From molecular mechanisms to therapeutic targets
2025
This review aims to provide a comprehensive overview of inflammatory signalling pathways and their pharmacological significance in human health and disease. Inflammation signifies a basic biological...
Bringing lab to the field: Exploring innovations in point-of-care diagnostics for the rapid detection and management of tropical diseases in resource-limited settings
2025
Tropical diseases present major health challenges in regions with limited resources, where access to advanced laboratory facilities is often scarce. This study explores the innovative techniques emerging...
Review on zebra fish as an alternative animal model for neurological studies
2025
Zebrafish (Danio rerio) have emerged as a powerful alternative animal model in neurological research due to their unique combination of genetic, anatomical, and physiological characteristics. Their...
Biomarkers in immunology: Their impact on immune function and response
2025
The immune system is a complex network of organs, tissues, and cells that plays a critical role in defending the body against life-threatening diseases such as infections, cancer, Alzheimer's, and Crohn's...
Multi-omics integration and machine learning reveal biomarker networks and therapeutic targets in Alzheimer's disease
November 2026
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited early diagnostic options and no curative therapy. This study presents a multi-region transcriptomic and systems biology...
Role of Akkermansia muciniphila in improving gut health for the prevention of type 2 diabetes
November 2026
Chronic inflammation, gut microbial dysbiosis, and metabolic dysregulation are closely interrelated and play a significant role in the pathogenesis of type 2 diabetes, a long-recognized global health...
Influence of deproteinization and demineralization process sequences on the physicochemical and structural characteristics of chitin isolated from Deep-sea mud shrimp (Solenocera hextii)
2022
Isolation of chitin from shrimp shell waste using chemical process is a well-adopted industrial practice due to its short process time and efficiency in removing both minerals and proteins from the...
Unraveling ankylosing spondylitis: Exploring the genetic and immunological factors and latest treatment innovations
2025
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis primarily affecting the spine and sacroiliac joints. Gut microbiota significantly affects ankylosing spondylitis (AS) pathophysiology....
An in-depth exploration of CNN-based deep learning models in cervical carcinoma analysis
November 2026
Cervical cancer has an extreme effect on women's health worldwide, recognized as the 4th most significant contributor to cancer fatalities among female. World Health Organization (WHO) states that there...
Leveraging lean 4.0 technologies in healthcare: An exploration of its applications
2024
Lean 4.0, a fusion of lean manufacturing and digital technologies, is a powerful tool for implementing Industry 4.0. Its widespread use across sectors is driven by its ability to eliminate waste, reduce...
Ayurveda constructs as functional biomarkers: A narrative review of translational perspective on Generalized anxiety disorder
2025
Anxiety disorders are among the most prevalent psychiatric conditions worldwide, yet the search for reliable biomarkers remains inconclusive. While modern biomedicine emphasizes measurable parameters...
The integration of artificial intelligence and biotechnology in medicine: accelerating novelty in biomarker-targeted discovery and drug delivery systems
November 2026
Artificial intelligence (AI) and biotechnology are two transformative fields converging to benefit STEM because of their reliance on data and models. The tools from both fields have redefined and improved...
Amoxicillin and cotrimoxazole-driven dysbiosis disrupted blood cell levels, cytokine balance and induced oxido-nitrosative stress in young mice
November 2026
Amoxicillin and cotrimoxazole are among the most frequently prescribed antibiotics, yet their impact on gut microbiota and systemic physiology, particularly during early life, remains a critical concern....
Role of cognitive computing in enhancing innovative healthcare solutions
2024
Cognitive computing represents a groundbreaking development in healthcare, encompassing technological platforms that emulate the human brain's functionality. While cloud computing offers on-demand internet...
In silico analysis of Coenzyme Q10 interaction with the heme-hemoglobin complex: Implications for oxidative stress and inflammation in severe malaria
November 2026
Plasmodium falciparum, the primary causative agent of severe malaria, catabolizes hemoglobin to obtain nutrients, resulting in the accumulation of toxic free heme. To mitigate this toxicity, the parasite...
Chemical fingerprint of Centella Asiatica’s bioactive compounds in the ethanolic and aqueous extracts
2020
Centella asiatica is a herbal plant that is widely used as medicine due to the benefit of its bioactive compounds such as rutin, kaempferol, quercetin, gallic acid, luteolin and catechin. Typically,...
Evaluation of withacoagulin from Withania coagulans for glycemic improvement and β-cell preservation in a type 2 diabetic model
November 2026
Type 2 diabetes mellitus remains a global health emergency, with existing therapies often failing to achieve durable glycemic control or preserve pancreatic β-cell function. In this study, we isolated...
FRF-HHO: Early ovarian cancer prediction using explainable fuzzy random forest optimized by Harris Hawks algorithm
November 2026
Ovarian cancer remains one of the most lethal gynecological malignancies, largely due to delayed diagnosis and the absence of reliable early screening tools. This study proposes an interpretable machine...
Identification of bipolar disorder related biomarkers, signaling pathways and potential therapeutic compounds based on bioinformatics methods and molecular docking technology
2025
Bipolar disorder (BD), also known as psychiatric disorder, affects millions of people all over the world. The aim of this investigation was to screen and verify hub genes involved in BD as well as to...
Protective effects of nutritional and polyphenolic supplementation in polycystic ovarian syndromes
November 2026
Hormonal abnormalities, insulin resistance, and chronic inflammation are the hallmarks of Polycystic Ovary Syndrome (PCOS), a prevalent endocrine condition affecting women of reproductive age. Oxidative...
Methanol extract of Smritisagara Rasa attenuates neurobehavior, neurochemical and stress indicators in rotenone-induced Drosophila model of Parkinson's disease
November 2026
Smritisagara Rasa (SSR), a traditional Ayurvedic herbo-mineral formulation, has long been prescribed for the treatment of Parkinson's disease (PD) since ancient times. Nevertheless, the underlying molecular...
Bridging traditional risk factors and genetic insights: A review on polygenic risk scores in cardiovascular diseases
2025
Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, with traditional risk models often falling short in predicting individual susceptibility-especially among diverse...