KeAi Talks: Translational Metabolic Syndrome Research Webinar

06 七月 2022, 09:30 - 11:30

Time:

Wednesday 6 July, 9:30 - 11:30 (Beijing time)

Agenda:

9:30 – 10:30 am

Suboptimal health

Wei Wang, MD, PhD, FFPH, FRSB, FRSM

Professor, Edith Cowan University, Australia

10:30 – 11:30 am

Association between insulin resistance and incidence of carotid atherosclerotic plaque: a cohort study

Yu-Xiang Yan, PhD

Professor, Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, China

 

Wei Wang, MD, PhD, FFPH, FRSB, FRSM

Professor, Centre for Precision Health, Edith Cowan University, Australia

Professor Wei Wang has published over 200 scientific papers in prestigious journals, including Science, Nature Genetics and The Lancet. He was the founding Chief Editor of the Journal of Family Medicine and Community Health. Currently he is Chief Editor of Translational Metabolic Syndrome Research, Associate Editor of EPMA Journal, and Regional Editor of Journal of Global Health and Journal of Human Hypertension. He is also Editor of Engineering and Guest Editor for Frontiers in Immunology. He has been elected a Fellow of the following organisations: Faculty of Public Health, Royal College of Physicians (2005), Royal Society of Biology (2016), and Royal Society of Medicine of the United Kingdom (2017).

Yu-Xiang Yan, PhD

Professor, Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, China

Professor Yu-Xiang Yan has been supported by the Beijing Young and Middle-Aged Key Teachers
Training Program, the Beijing Excellent Talents Subsidy Program, and the Beijing Youth Top Talents Training Program. Over the past 10 years, her research projects have included three funded by the National Natural Science Foundation of China and two by the Beijing Municipality Natural Science
Foundation. She has published over 60 scientific papers. She is also a member of the Cancer Prevention and Control Committee of the Chinese Preventive Medicine Association, the Clinical Efficacy Evaluation Committee of the World Federation of Traditional Chinese Medicine, and the Health Care Big Data Society of the National Industrial Statistics Teaching and Research Association, et al.

Contact: Mr. Lei Jiang, leo.jiang@keaipublishing.com

Zoom link:
https://keaipublishing.zoom.us/j/85390701464?pwd=QU84QXFKL0QyQmpqdWZJbjg4eHIydz09

Meeting ID: 853 9070 1464

Password: 6677

Topic 1: Suboptimal health

Suboptimal health status (SHS) is the physical state between health and disease, characterised by ambiguous health complaints in the absence of a diagnosable condition. Detecting SHS can predict the risk of certain chronic diseases before their onset, providing a window of opportunity to halt or reverse their progress.
In this webinar, delegates will be introduced to concepts that can 1) predict a person’s predisposition to disease before its onset, 2) reduce the prevalence of chronic diseases, and 3) challenge established practices using a robust evidence base.

Following the webinar, participants will be able to: 

  • Understand that the current biomedical model of health has a reactive, delayed approach to treating non-communicable chronic diseases (NCD), i.e., treatments are implemented after disease onset. 
  • Learn that SHS is aligning with predictive, preventive and personalised medicine (PPPM) by moving to a pro-active approach when managing NCD, i.e., identifying people at risk of developing chronic disease and initiating interventions earlier. 
  • Understand that self-claimed “normal” health status may not represent health, because asymptomatic subjects may carry chronic diseases at their early stage, such as cancer, diabetes mellitus and atherosclerosis. 
  • Design and plan according to clinical needs, heterogeneity and uncontrollability in precaution health studies. 

Topic 2: Association between insulin resistance and incidence of carotid atherosclerotic plaque: a cohort study

Insulin resistance (IR) is a state in which physiologic concentrations of insulin produce a subnormal biologic response. IR is associated with a variety of risk factors of cardiovascular diseases (CVDs), including central obesity, essential hypertension, hypertriglyceridemia and low HDL cholesterol. CVDs are the leading cause of premature death among chronic non-communicable diseases. As the key pathological process in most CVDs, the progression of atherosclerosis is strongly associated with the risk of CVDs.

In this webinar, delegates will be introduced to the following concepts: 1) insulin resistance, 2) IR as an independent risk factor of atherosclerosis, and 3) the potential mechanics of the association between IR and atherosclerosis.

Following the webinar, participants will be able to: 

  • Understand the research progress of the association between IR and atherosclerosis.
  • Understand the association between IR and carotid plaque in a functional community cohort by using HOMA-IR and triglyceride glucose (TyG) indexes simultaneously.
  • Design and analyse a cohort study concerning risk factors and NCD.

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